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The combination of microwave and microfluidic technologies has the potential to enable wireless monitoring and interaction with bioparticles, facilitating in this way the exploration of a still largely uncharted territory at the…

Systems and Control · Electrical Eng. & Systems 2022-09-21 Cesar Palacios , Marc Jofre , Lluis Jofre , Jordi Romeu , Luis Jofre-Roca

Developing an organoid computing platform from neurons in vitro demands stable, precisely controlled microenvironments. To address this requirement, we designed, simulated, and fabricated a microfluidic device featuring hexagonal wells…

Fluid Dynamics · Physics 2025-08-04 Maxx Yung

Microfluidic NMR spectroscopy can probe chemical and bio-chemical processes non-invasively in a tightly controlled environment. We present a dual-channel modular probe assembly for high efficiency microfluidic NMR spectroscopy and imaging.…

Instrumentation and Detectors · Physics 2019-05-22 Manvendra Sharma , Marcel Utz

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) derived from somatic cells (SCs) provide promising resources for regenerative medicine and medical research, leading to a daily identification of new cell lines.…

Quantitative Methods · Quantitative Biology 2013-02-15 Anyou Wang

We present a novel multi-modal bio-sensing platform capable of integrating multiple data streams for use in real-time applications. The system is composed of a central compute module and a companion headset. The compute node collects,…

Human-Computer Interaction · Computer Science 2018-02-23 Siddharth , Aashish Patel , Tzyy-Ping Jung , Terrence J. Sejnowski

A novel microfabricated, all-electrical measurement platform is presented for a direct, accurate and rapid determination of the thermal conductivity and diffusivity of liquid and solid materials. The measurement approach is based on the…

The problem of inferring proteins from complex peptide cocktails (digestion products of biological samples) in shotgun proteomic workflow sets extreme demands on computational resources in respect of the required very high processing…

Computational Engineering, Finance, and Science · Computer Science 2014-12-30 S. M. Vidanagamachchi , S. D. Dewasurendra , R. G. Ragel , M. Niranjan

Plasmonic metamaterials can be used to enhance mid-infrared sensors and detectors for immunosensing applications. The major challenge is to integrate these technologies in low-cost, compact, and promising platforms. In this study, as an…

The combination of different imaging modalities into single imaging platforms has a strong potential in biomedical sciences since it permits the analysis of complementary properties of the target sample. Here, we report on an extremely…

Optics · Physics 2025-01-17 David Alonso , Javier Garcia , Vicente Mico

A central challenge in every field of biology is to use existing measurements to predict the outcomes of future experiments. In this work, we consider the wealth of antibody inhibition data against variants of the influenza virus. Due to…

Quantitative Methods · Quantitative Biology 2023-07-27 Tal Einav , Rong Ma

Rapid identification of microparticles in liquid is an important problem in environmental and biomedical applications such as for microplastic detection in water sources and physiological fluids. Existing spectro-scopic techniques are…

Applied Physics · Physics 2024-11-20 Yagmur Ceren Alatas , Uzay Tefek , Sayedus Salehin , Hashim Alhmoud , M. Selim Hanay

Absolute quantification of biological samples entails determining expression levels in precise numerical copies, offering enhanced accuracy and superior performance for rare templates. However, existing methodologies suffer from significant…

Quantitative Methods · Quantitative Biology 2023-09-06 Yuanyuan Wei , Sai Mu Dalike Abaxi , Nawaz Mehmood , Luoquan Li , Fuyang Qu , Guangyao Cheng , Dehua Hu , Yi-Ping Ho , Scott Wu Yuan , Ho-Pui Ho

Molecular Communications (MC), transferring information via chemical signals, holds promise for transformative healthcare applications within the Internet of Bio-Nano Things (IoBNT) framework. Despite promising advances toward practical MC…

Emerging Technologies · Computer Science 2025-02-03 Maide Miray Albay , Eren Akyol , Fariborz Mirlou , Levent Beker , Murat Kuscu

Motivation: Flow Injection Analysis coupled to High-Resolution Mass Spectrometry (FIA-HRMS) is a promising approach for high-throughput metabolomics. FIA-HRMS data, however, cannot be preprocessed with current software tools which rely on…

Quantitative Methods · Quantitative Biology 2017-08-15 Alexis Delabrière , Ulli Hohenester , Benoit Colsch , Christophe Junot , François Fenaille , Etienne Thévenot

Online, comprehensive molecular profiling of exhaled breath provides a non-invasive window into human metabolism, yet current optical platforms are restricted by narrow instantaneous spectral coverage. Here, we present a novel…

Ensemble averaging experiments may conceal many fundamental molecular interactions. To overcome that, a high-throughput detection of single molecules or colloidal nanodots is crucial for biomedical, nanoelectronic, and solid-state…

Biological Physics · Physics 2019-07-15 Siddharth Ghosh , Narain Karedla , Ingo Gregor

Multiparameter estimation is a general problem that aims at measuring unknown physical quantities, obtaining high precision in the process. In this context, the adoption of quantum resources promises a substantial boost in the achievable…

Digital microfluidic (DMF) biochips are now being extensively used to automate several biochemical laboratory protocols such as clinical analysis, point-of-care diagnostics, and polymerase chain reaction (PCR). In many biological assays,…

Emerging Technologies · Computer Science 2013-07-05 Sukanta Bhattacharjee , Ansuman Banerjee , Tsung-Yi Ho , Krishnendu Chakrabarty , Bhargab B. Bhattacharya

This paper studies microfluidic molecular communication receivers with finite-capacity Langmuir adsorption driven by an effective surface concentration. In the reaction-limited regime, we derive a closed-form single-pulse response kernel…

Signal Processing · Electrical Eng. & Systems 2026-01-19 Ruifeng Zheng , Pengjie Zhou , Pit Hofmann , Martín Schottlender , Fatima Rani , Juan A. Cabrera , Frank H. P. Fitzek

We have developed a microfluidic tool to measure the diffusion coefficient $D$ of solutes in an aqueous solution, by following the temporal relaxation of an initially steep concentration gradient in a microchannel. Our chip exploits…

Soft Condensed Matter · Physics 2022-08-23 Hoang-Thanh Nguyen , Anne Bouchaudy , Jean-Baptiste Salmon