Related papers: Geometry of Morphogenesis
The shape of homogeneous, generic, smooth convex bodies as described by the Euclidean distance with nondegenerate critical points, measured from the center of mass represents a rather restricted class M_C of Morse-Smale functions on S^2.…
Embedding of the brane metric into Euclidean (2+4)-space is found. Brane geometry can be visualized as the surface of the hyper-sphere in six dimensions which 'radius' is governed by the cosmological constant. Minkowski space in this…
In many tissues, cell type varies over single-cell length-scales, creating detailed spatial heterogeneities fundamental to physiological function. To gain understanding of this relationship between tissue function and detailed structure,…
Cell growth, division and death are defining features of biological tissues that contribute to morphogenesis. In hydrodynamic descriptions of cohesive tissues, their occurrence implies a non-zero rate of variation of cell density. We show…
The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…
We describe all families of star-shaped n-polygons in the Euclidean plane with prescribed perimeter and area ; they are leaves of a foliation F on the space of star-shaped n-polygons. By the way, we study some geometric properties of convex…
Numerical investigation of the interaction of electromagnetic fields with eukaryotic cells requires specifically adapted computer models. Virtual microdosimetry, used to investigate exposure, requires volumetric cell models, which are…
Most biological tissues grow by the synthesis of new material close to the tissue's interface, where spatial interactions can exert strong geometric influences on the local rate of growth. These geometric influences may be mechanistic, or…
The migratory dynamics of cells can be influenced by the complex micro-environment through which they move. It remains unclear how the motility machinery of confined cells responds and adapts to their micro-environment. Here, we propose a…
The space-time geometry is considered to be a physical geometry, i.e. a geometry described completely by the world function. All geometrical concepts and geometric objects are taken from the proper Euclidean geometry. They are expressed via…
Collective cell movement, characterized by multiple cells that are in contact for substantial periods of time and undergo correlated motion, plays a central role in cancer and embryogenesis. Recent imaging experiments have provided…
Rapid advance of experimental techniques provides an unprecedented in-depth view into complex developmental processes. Still, little is known on how the complexity of multicellular organisms evolved by elaborating developmental programs and…
A new model for biological growth is introduced that couples the geometry of an organism (or part of the organism) to the flow and deposition of material. The model has three dynamical variables (a) a Riemann metric tensor for the geometry,…
A method is proposed for the characterisation of the entropy of cellular structures, based on the compactivity concept for granular packings. Hamiltonian-like volume functions are constructed both in two and in three dimensions, enabling…
The topology and form finding of tensegrity structures have been studied extensively since the introduction of the tensegrity concept. However, most of these studies address topology and form separately, where the former represented a…
The large-scale structure of the Universe is well approximated by the Friedmann equations, parametrized by several energy densities which can be observationally inferred. A natural question to ask is: How different would the Universe be if…
One considers geometry with the intransitive equaivalence relation. Such a geometry is a physical geometry, i.e. it is described completely by the world function, which is a half of the squared distance function. The physical geometry…
The structure of topological spaces is analysed here through the lenses of fibrous preorders. Each topological space has an associated fibrous preorder and those fibrous preorders which return a topological space are called spacial. A…
Cross-sections of cell shapes in a tissue monolayer typically resemble a tiling of convex polygons. Yet, examples exist where the polygons are not convex with curved cell-cell interfaces, as seen in the adaxial epidermis. To date,…
We say that a metric graph is uniformly bounded if the degrees of all vertices are uniformly bounded and the lengths of edges are pinched between two positive constants; a metric space is approximable by a uniform graph if there is one…