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Related papers: Annotating Synapses in Large EM Datasets

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The field of connectomics faces unprecedented "big data" challenges. To reconstruct neuronal connectivity, automated pixel-level segmentation is required for petabytes of streaming electron microscopy data. Existing algorithms provide…

One of the central problems in neuroscience is reconstructing synaptic connectivity in neural circuits. Synapses onto a neuron can be probed by sequentially stimulating potentially pre-synaptic neurons while monitoring the membrane voltage…

Neurons and Cognition · Quantitative Biology 2012-10-05 Tao Hu , Dmitri B. Chklovskii

Accurate segmentation of organelle instances from electron microscopy (EM) images plays an essential role in many neuroscience researches. However, practical scenarios usually suffer from high annotation costs, label scarcity, and large…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Dafei Qiu , Shan Xiong , Jiajin Yi , Jialin Peng

Although deep encoder-decoder networks have achieved astonishing performance for mitochondria segmentation from electron microscopy (EM) images, they still produce coarse segmentations with lots of discontinuities and false positives.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-30 Zhimin Yuan , Jiajin Yi , Zhengrong Luo , Zhongdao Jia , Jialin Peng

Sleep spindles are neurophysiological phenomena that appear to be linked to memory formation and other functions of the central nervous system, and that can be observed in electroencephalographic recordings (EEG) during sleep. Manually…

Signal Processing · Electrical Eng. & Systems 2022-05-12 Lars Kaulen , Justus T. C. Schwabedal , Jules Schneider , Philipp Ritter , Stephan Bialonski

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

The success of deep learning in computer vision has greatly increased the need for annotated image datasets. We propose an EEG (Electroencephalogram)-based image annotation system. While humans can recognize objects in 20-200 milliseconds,…

Computer Vision and Pattern Recognition · Computer Science 2017-11-08 Viral Parekh , Ramanathan Subramanian , Dipanjan Roy , C. V. Jawahar

Etruscan mirrors constitute a significant category in Etruscan art, characterized by elaborate figurative illustrations featured on their backside. A laborious and costly aspect of their analysis and documentation is the task of manually…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 Rafael Sterzinger , Christian Stippel , Robert Sablatnig

We propose a meta-learning method for learning from multiple noisy annotators. In many applications such as crowdsourcing services, labels for supervised learning are given by multiple annotators. Since the annotators have different skills…

Machine Learning · Computer Science 2025-06-13 Atsutoshi Kumagai , Tomoharu Iwata , Taishi Nishiyama , Yasutoshi Ida , Yasuhiro Fujiwara

The most established method of reconstructing neural circuits from animals involves slicing tissue very thin, then taking mosaics of electron microscope (EM) images. To trace neurons across different images and through different sections,…

Quantitative Methods · Quantitative Biology 2013-04-23 Louis K. Scheffer , Bill Karsh , Shiv Vitaladevun

Instance segmentation in electron microscopy (EM) volumes is tough due to complex shapes and sparse annotations. Self-supervised learning helps but still struggles with intricate visual patterns in EM. To address this, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Yinda Chen , Wei Huang , Xiaoyu Liu , Shiyu Deng , Qi Chen , Zhiwei Xiong

Accurate instrument segmentation in endoscopic vision of robot-assisted surgery is challenging due to reflection on the instruments and frequent contacts with tissue. Deep neural networks (DNN) show competitive performance and are in favor…

Computer Vision and Pattern Recognition · Computer Science 2024-07-01 Haonan Peng , Shan Lin , Daniel King , Yun-Hsuan Su , Randall A. Bly , Kris S. Moe , Blake Hannaford

Active learning enhances annotation efficiency by selecting the most revealing samples for labeling, thereby reducing reliance on extensive human input. Previous methods in semantic segmentation have centered on individual pixels or small…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Jinchao Ge , Zeyu Zhang , Minh Hieu Phan , Bowen Zhang , Akide Liu , Yang Zhao , Shuwen Zhao

Recent successes in deep learning have started to impact neuroscience. Of particular significance are claims that current segmentation algorithms achieve "super-human" accuracy in an area known as connectomics. However, as we will show,…

Computer Vision and Pattern Recognition · Computer Science 2020-01-20 Drew Linsley , Junkyung Kim , David Berson , Thomas Serre

The tracing of neural pathways through large volumes of image data is an incredibly tedious and time-consuming process that significantly encumbers progress in neuroscience. We are exploring deep learning's potential to automate…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Ishtar Nyawira , Kristi Bushman , Iris Qian , Annie Zhang

Efforts to automate the reconstruction of neural circuits from 3D electron microscopic (EM) brain images are critical for the field of connectomics. An important computation for reconstruction is the detection of neuronal boundaries. Images…

Computer Vision and Pattern Recognition · Computer Science 2015-08-21 Kisuk Lee , Aleksandar Zlateski , Ashwin Vishwanathan , H. Sebastian Seung

The size of image stacks in connectomics studies now reaches the terabyte and often petabyte scales with a great diversity of appearance across brain regions and samples. However, manual annotation of neural structures, e.g., synapses, is…

Computer Vision and Pattern Recognition · Computer Science 2023-02-02 Jingpeng Wu , Yicong Li , Nishika Gupta , Kazunori Shinomiya , Pat Gunn , Alexey Polilov , Hanspeter Pfister , Dmitri Chklovskii , Donglai Wei

Automatic Music Transcription (AMT) converts audio recordings into symbolic musical representations. Training deep neural networks (DNNs) for AMT typically requires strongly aligned training pairs with precise frame-level annotations. Since…

Sound · Computer Science 2025-11-19 Jonathan Yaffe , Ben Maman , Meinard Müller , Amit H. Bermano

Image collections, if critical aspects of image content are exposed, can spur research and practical applications in many domains. Supervised machine learning may be the only feasible way to annotate very large collections, but leading…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Sara Mousavi , Ramin Nabati , Megan Kleeschulte , Audris Mockus

Electron microscopic connectomics is an ambitious research direction with the goal of studying comprehensive brain connectivity maps by using high-throughput, nano-scale microscopy. One of the main challenges in connectomics research is…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Tran Minh Quan , David G. C. Hildebrand , Won-Ki Jeong