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Related papers: Annotating Synapses in Large EM Datasets

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In the last years, automated segmentation has become a necessary tool for volume electron microscopy (EM) imaging. So far, the best performing techniques have been largely based on fully supervised encoder-decoder CNNs, requiring a…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Joris Roels , Julian Hennies , Yvan Saeys , Wilfried Philips , Anna Kreshuk

We present a method for microtubule tracking in electron microscopy volumes. Our method first identifies a sparse set of voxels that likely belong to microtubules. Similar to prior work, we then enumerate potential edges between these…

Computer Vision and Pattern Recognition · Computer Science 2020-09-18 Nils Eckstein , Julia Buhmann , Matthew Cook , Jan Funke

Extracellular, large scale in vivo recording of neural activity is mandatory for elucidating the interaction of neurons within large neural networks at the level of their single unit activity. Technological achievements in MEMS-based…

Neurons and Cognition · Quantitative Biology 2017-07-03 Patrick Ruther , Oliver Paul

Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Ning Zhang , Susan Francis , Rayaz Malik , Xin Chen

Embedded devices are omnipresent in modern networks including the ones operating inside critical environments. However, due to their constrained nature, novel mechanisms are required to provide external, and non-intrusive anomaly detection.…

Cryptography and Security · Computer Science 2023-02-07 Kurt A. Vedros , Georgios Michail Makrakis , Constantinos Kolias , Robert C. Ivans , Craig Rieger

To build the connectomics map of the brain, we developed a new algorithm that can automatically refine the Membrane Detection Probability Maps (MDPM) generated to perform automatic segmentation of electron microscopy (EM) images. To achieve…

Neural and Evolutionary Computing · Computer Science 2015-06-22 Xundong Wu

Diagnosis based on medical images, such as X-ray images, often involves manual annotation of anatomical keypoints. However, this process involves significant human efforts and can thus be a bottleneck in the diagnostic process. To fully…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jinhee Kim , Taesung Kim , Taewoo Kim , Jaegul Choo , Dong-Wook Kim , Byungduk Ahn , In-Seok Song , Yoon-Ji Kim

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

Data is the engine of modern computer vision, which necessitates collecting large-scale datasets. This is expensive, and guaranteeing the quality of the labels is a major challenge. In this paper, we investigate efficient annotation…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Yuan-Hong Liao , Amlan Kar , Sanja Fidler

In this paper, we present a new pipeline which automatically identifies and annotates axoplasmic reticula, which are small subcellular structures present only in axons. We run our algorithm on the Kasthuri11 dataset, which was color…

Curating fully annotated datasets for medical image segmentation is labour-intensive and expertise-demanding. To alleviate this problem, prior studies have explored scribble annotations for weakly supervised segmentation. Existing solutions…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Ke Zhang , Bomin Wang , Hangqi Zhou , Xiahai Zhuang

Deep-learning-based pipelines have shown the potential to revolutionalize microscopy image diagnostics by providing visual augmentations to a trained pathology expert. However, to match human performance, the methods rely on the…

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

This paper aims to reduce the time to annotate images for panoptic segmentation, which requires annotating segmentation masks and class labels for all object instances and stuff regions. We formulate our approach as a collaborative process…

Computer Vision and Pattern Recognition · Computer Science 2020-12-16 Jasper R. R. Uijlings , Mykhaylo Andriluka , Vittorio Ferrari

Automatic cell image segmentation methods in connectomics produce merge and split errors, which require correction through proofreading. Previous research has identified the visual search for these errors as the bottleneck in interactive…

Computer Vision and Pattern Recognition · Computer Science 2017-04-05 Daniel Haehn , Verena Kaynig , James Tompkin , Jeff W. Lichtman , Hanspeter Pfister

The electron microscope (EM) remains the predominant technique for elucidating intricate details of the animal nervous system at the nanometer scale. However, accurately reconstructing the complex morphology of axons and myelin sheaths…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Ao Cheng , Guoqiang Zhao , Lirong Wang , Ruobing Zhang

Single-cell RNA sequencing has transformed our ability to identify diverse cell types and their transcriptomic signatures. However, annotating these signatures-especially those involving poorly characterized genes-remains a major challenge.…

Training segmentation models from scratch has been the standard approach for new electron microscopy connectomics datasets. However, leveraging pretrained models from existing datasets could improve efficiency and performance in constrained…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Shashata Sawmya , Thomas L. Athey , Gwyneth Liu , Nir Shavit

Annotating biomedical images for supervised learning is a complex and labor-intensive task due to data diversity and its intricate nature. In this paper, we propose an innovative method, the efficient one-pass selective annotation (EPOSA),…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Yuli Wang , Peiyu Duan , Zhangxing Bian , Anqi Feng , Yuan Xue

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Yunpeng Xiao , Youpeng Zhao , Ge Yang