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The critical behavior of Ising model on a one-dimensional network, which has long-range connections at distances $l>1$ with the probability $\Theta(l)\sim l^{-m}$, is studied by using Monte Carlo simulations. Through studying the Ising…

Pattern Formation and Solitons · Physics 2009-11-13 YunFeng Chang , Liang Sun , Xu Cai

We explore the large-scale behavior of nucleotide compositional strand asymmetries along human chromosomes. As we observe for 7 of 9 origins of replication experimentally identified so far, the (TA+GC) skew displays rather sharp upward…

The distribution of bases spacing in human genome was investigated. An analysis of the frequency of occurrence in the human genome of different sequence lengths flanked by one type of nucleotide was carried out showing that the distribution…

Other Quantitative Biology · Quantitative Biology 2019-04-18 Andrzej Z. Górski , Monika Piwowar

The replicated field theory of the random field Ising model involves the couplings of replicas of different indices. The resulting correlation functions involve a superposition of different types of long distance behaviours. However the…

Condensed Matter · Physics 2009-10-31 E. Brézin , De Dominicis

We consider force-induced unzipping transition for a heterogeneous DNA model with a correlated base-sequence. Both finite-range and long-range correlated situations are considered. It is shown that finite-range correlations increase…

Soft Condensed Matter · Physics 2009-11-10 A. E. Allahverdyan , Zh. S. Gevorkian , Chin-Kun Hu , Ming-Chya Wu

The study of correlation structure in the primary sequences of DNA is reviewed. The issues reviewed include: symmetries among 16 base-base correlation functions, accurate estimation of correlation measures, the relationship between $1/f$…

adap-org · Physics 2009-11-10 Wentian Li

Large-scale dynamical properties of complete chromosome DNA sequences of eukaryotes are considered. By the proposed deterministic models with intermittency and symbolic dynamics we describe a wide spectrum of large-scale patterns inherent…

Genomics · Quantitative Biology 2015-05-27 Sergei Rybalko , Sergei Larionov , Maria Poptsova , Alexander Loskutov

This paper examines two methods for finding whether long-range correlations exist in DNA: a fractal measure and a mutual information technique. We evaluate the performance and implications of these methods in detail. In particular we…

Populations and Evolution · Quantitative Biology 2007-05-23 Matthew J. Berryman , Andrew Allison , Derek Abbott

Simple elastic network models of DNA were developed to reveal the structure-dynamics relationships for several nucleotide sequences. First, we propose a simple all-atom elastic network model of DNA that can explain the profiles of…

Biological Physics · Physics 2016-02-17 Shuhei Isami , Naoaki Sakamoto , Hiraku Nishimori , Akinori Awazu

We consider a measure given as the continuum limit of a one-dimensional Ising model with long-range translationally invariant interactions. Mathematically, the measure can be described by a self-interacting Poisson driven jump process. We…

Mathematical Physics · Physics 2022-01-20 David Hasler , Benjamin Hinrichs , Oliver Siebert

A structural genetic model incorporating a modern understanding of the genome and common practice in genome-wide association studies is derived mathematically. The model shows the Haldane map distance as a direct consequence of the…

Genomics · Quantitative Biology 2022-05-24 Christopher Salahub

Based on a model first studied in [Physical Review A, vol. 43, 5240-5260,1991] properties of correlation function for expansion-modification systems are developed. The existence of several characteristic exponents is proved. The…

chao-dyn · Physics 2016-08-31 R. Mansilla , G. Cocho

Long-range correlation, a property of time series exhibiting long-term memory, is mainly studied in the statistical physics domain and has been reported to exist in natural language. Using a state-of-the-art method for such analysis,…

Computation and Language · Computer Science 2017-12-12 Kumiko Tanaka-Ishii

Correlations between two variables of a high-dimensional system can be indicative of an underlying interaction, but can also result from indirect effects. Inverse Ising inference is a method to distinguish one from the other. Essentially,…

Populations and Evolution · Quantitative Biology 2014-12-10 Benedikt Obermayer , Erel Levine

We investigate the localization property of an electron in the disordered two-chain system (ladder model) with long-range correlation as a simple model for electronic property in DNA sequence. The chains are constructed by repetition of the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Hiroaki Yamada

Much of the on-going statistical analysis of DNA sequences is focused on the estimation of characteristics of coding and non-coding regions that would possibly allow discrimination of these regions. In the current approach, we concentrate…

Genomics · Quantitative Biology 2009-11-10 D. Kugiumtzis , A. Provata

We propose a novel combination of methods that (i) portrays quantitative characteristics of a DNA sequence as an image, (ii) computes distances between these images, and (iii) uses these distances to output a map wherein each sequence is a…

Genomics · Quantitative Biology 2013-07-16 Lila Kari , Kathleen A. Hill , Abu Sadat Sayem , Nathaniel Bryans , Katelyn Davis , Nikesh S. Dattani

We consider learning ancestral causal relationships in high dimensions. Our approach is driven by a supervised learning perspective, with discrete indicators of causal relationships treated as labels to be learned from available data. We…

Machine Learning · Statistics 2019-05-29 Umberto Noè , Bernd Taschler , Joachim Täger , Peter Heutink , Sach Mukherjee

Herein it is shown that in order to study the statistical properties of DNA sequences in bacterial chromosomes it suffices to consider only one half of the chromosome because they are similar to its corresponding complementary sequence in…

Genomics · Quantitative Biology 2009-11-10 Marco V. Jose , Tzipe Govezensky , Juan R. Bobadilla

We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this class of non-equilibrium models is developed by adopting…

Biological Physics · Physics 2007-05-23 Peter F. Arndt , Christopher B. Burge , Terence Hwa