English

The Study of Correlation Structures of DNA Sequences: A Critical Review

adap-org 2009-11-10 v1 Adaptation and Self-Organizing Systems Genomics

Abstract

The study of correlation structure in the primary sequences of DNA is reviewed. The issues reviewed include: symmetries among 16 base-base correlation functions, accurate estimation of correlation measures, the relationship between 1/f1/f and Lorentzian spectra, heterogeneity in DNA sequences, different modeling strategies of the correlation structure of DNA sequences, the difference of correlation structure between coding and non-coding regions (besides the period-3 pattern), and source of broad distribution of domain sizes. Although some of the results remain controversial, a body of work on this topic constitutes a good starting point for future studies.

Keywords

Cite

@article{arxiv.adap-org/9704003,
  title  = {The Study of Correlation Structures of DNA Sequences: A Critical Review},
  author = {Wentian Li},
  journal= {arXiv preprint arXiv:adap-org/9704003},
  year   = {2009}
}

Comments

LaTeX, two figures, postscript is expected to be 46 pages. To appear in the special issue of Computer & Chemistry (1997)