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A particular case of the famous quasispecies model - the Crow-Kimura model with a permutation invariant fitness landscape - is investigated. Using the fact that the mutation matrix in the case of a permutation invariant fitness landscape…

Populations and Evolution · Quantitative Biology 2014-08-21 Alexander S. Bratus , Artem S. Novozhilov , Yuri S. Semenov

We consider finite population size effects for Crow-Kimura and Eigen quasispecies models with single peak fitness landscape. We formulate accurately the iteration procedure for the finite population models, then derive Hamilton-Jacobi…

Populations and Evolution · Quantitative Biology 2015-06-12 David B. Saakian , Michael W. Deem , Chin Kun Hu

This work presents a population genetic model of evolution, which includes haploid selection, mutation, recombination, and drift. The mutation-selection equilibrium can be expressed exactly in closed form for arbitrary fitness functions…

Populations and Evolution · Quantitative Biology 2023-02-28 Jenny M. Poulton , Lee Altenberg , Chris Watkins

We study the question of existence of positive steady states of nonlinear evolution equations. We recast the steady state equation in the form of eigenvalue problems for a parametrised family of unbounded linear operators, which are…

Analysis of PDEs · Mathematics 2019-03-25 Àngel Calsina , József Z. Farkas

The Kimura equation is a degenerated partial differential equation of drift-diffusion type used in population genetics. Its solution is required to satisfy not only the equation but a series of conservation laws formulated as integral…

Analysis of PDEs · Mathematics 2022-08-02 Fabio A. C. C. Chalub

We study the population genetics of two neutral alleles under reversible mutation in the \Lambda-processes, a population model that features a skewed offspring distribution. We describe the shape of the equilibrium allele frequency…

Populations and Evolution · Quantitative Biology 2013-06-21 Ricky Der , Joshua B. Plotkin

We study a family of selection-mutation models of a sexual population structured by a phenotypical trait. The main feature of these models is the asymmetric trait heredity or fecundity between the parents : we assume that each individual…

Analysis of PDEs · Mathematics 2022-04-11 Benoît Perthame , Martin Strugarek , Cécile Taing

In this paper, we study an integro-differential equation which describes the evolutionary dynamics of a population structured by a phenotypic trait. This population undergoes asexual reproduction, competition, selection, and mutation. We…

Analysis of PDEs · Mathematics 2025-11-18 Caroline Guinet , Sepideh Mirrahimi , Jean-Michel Roquejoffre

We study a birth and death model for the adapatation of a sexual population to an environment. The population is structured by a phenotypical trait, and, possibly, an age variable. Recombination is modeled by Fisher's infinitesimal…

Populations and Evolution · Quantitative Biology 2017-03-28 Thibault Bourgeron , Vincent Calvez , Jimmy Garnier , Thomas Lepoutre

We consider an asexual biological population of constant size $N$ evolving in discrete time under the influence of selection and mutation. Beneficial mutations appear at rate $U$ and their selective effects $s$ are drawn from a distribution…

Populations and Evolution · Quantitative Biology 2015-05-14 Su-Chan Park , Damien Simon , Joachim Krug

A probability model is presented for the dynamics of mutation-selection balance in a haploid infinite-population infinite-sites setting sufficiently general to cover mutation-driven changes in full age-specific demographic schedules. The…

Populations and Evolution · Quantitative Biology 2007-05-23 David Steinsaltz , Steven N. Evans , Kenneth W. Wachter

This paper is concerned with the evolution of haploid organisms that reproduce asexually. In a seminal piece of work, Eigen and coauthors proposed the quasispecies model in an attempt to understand such an evolutionary process. Their work…

Populations and Evolution · Quantitative Biology 2012-03-07 Narendra M. Dixit , Piyush Srivastava , Nisheeth K. Vishnoi

In this paper, we deal with the equilibrium selection problem, which amounts to steering a population of individuals engaged in strategic game-theoretic interactions to a desired collective behavior. In the literature, this problem has been…

Systems and Control · Electrical Eng. & Systems 2025-11-11 Lorenzo Zino , Mengbin Ye , Giuseppe Carlo Calafiore , Alessandro Rizzo

We discuss a population of sequences subject to mutations and frequency-dependent selection, where the fitness of a sequence depends on the composition of the entire population. This type of dynamics is crucial to understand the evolution…

Disordered Systems and Neural Networks · Physics 2009-11-07 M. Laessig , L. Peliti , F. Tria

Momentum-space representation renders an interesting perspective to theory of large fluctuations in populations undergoing Markovian stochastic gain-loss processes. This representation is obtained when the master equation for the…

Statistical Mechanics · Physics 2015-05-18 Michael Assaf , Baruch Meerson , Pavel V. Sasorov

Predicting the adaptation of populations to a changing environment is crucial to assess the impact of human activities on biodiversity. Many theoretical studies have tackled this issue by modeling the evolution of quantitative traits…

Analysis of PDEs · Mathematics 2022-06-28 Jimmy Garnier , O Cotto , T Bourgeron , E Bouin , T Lepoutre , O Ronce , V Calvez

We investigate the equilibrium state of the model of Peng, \textit{et al.} for molecular breeding. In the model, a population of DNA sequences is successively culled by removing the sequences with the lowest binding affinity to a particular…

Statistical Mechanics · Physics 2007-05-23 Elisheva Cohen , David A. Kessler

We considered a {multi-block} molecular model of biological evolution, in which fitness is a function of the mean types of alleles located at different parts (blocks) of the genome. We formulated an infinite population model with selection…

Populations and Evolution · Quantitative Biology 2015-06-12 David B. Saakian , Zara Kirakosyan , Chin-Kun Hu

We are interested in the dynamics of a population structured by a phenotypic trait. Individuals reproduce sexually, which is represented by a non-linear integral operator. This operator is combined to a multiplicative operator representing…

Analysis of PDEs · Mathematics 2021-04-14 Gaël Raoul

We provide an asymptotic analysis of a nonlinear integro-differential equation which describes the evolutionary dynamics of a population which reproduces sexually and which is subject to selection and competition. The sexual reproduction is…

Analysis of PDEs · Mathematics 2026-03-27 M Hillairet , S Mirrahimi
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