English
Related papers

Related papers: The zero-patient problem with noisy observations

200 papers

A common challenge in the natural sciences is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual…

Machine Learning · Computer Science 2025-10-08 Sebastian Wagner-Carena , Aizhan Akhmetzhanova , Sydney Erickson

We propose a simple SIR model in order to investigate the impact of various confinement strategies on a most virulent epidemic. Our approach is motivated by the current COVID-19 pandemic. The main hypothesis is the existence of two…

Populations and Evolution · Quantitative Biology 2020-12-30 G. Nakamura , B. Grammaticos , M. Badoual

This paper develops and analyzes optimization models for rapid detection of viruses in large contact networks. In the model, a virus spreads in a stochastic manner over an undirected connected graph, under various assumptions on the spread…

Optimization and Control · Mathematics 2021-06-16 Sudesh K. Agrawal , John J. Hasenbein

We study an epidemic propagation between $M$ population centra. The novelty of the model is in analyzing the migration of host (remaining in the same centre) and guest (migrated to another centre) populations separately. Even in the…

Populations and Evolution · Quantitative Biology 2014-01-28 Igor Sazonov , Mark Kelbert , Michael B. Gravenor

What role do asymptomatically infected individuals play in the transmission dynamics? There are many diseases, such as norovirus and influenza, where some infected hosts show symptoms of the disease while others are asymptomatically…

Populations and Evolution · Quantitative Biology 2018-01-29 Ka Yin Leung , Pieter Trapman , Tom Britton

The epidemic spreading on arbitrary complex networks is studied in SIR (Susceptible Infected Recovered) compartment model. We propose our implementation of a Naive SIR algorithm for epidemic simulation spreading on networks that uses data…

Data Structures and Algorithms · Computer Science 2015-03-20 Nino Antulov-Fantulin , Alen Lancic , Hrvoje Stefancic , Mile Sikic

The epidemic spreading of a disease can be described by a contact network whose nodes are persons or centers of contagion and links heterogeneous relations among them. We provide a procedure to identify multiple sources of an outbreak or…

Mathematical Physics · Physics 2012-11-13 Vincenzo Fioriti , Marta Chinnici

We investigate the long-time dynamics of a SIR epidemic model in the case of a population of pathogens infecting a homogeneous host population. The pathogen population is structured by a genotypic variable. When the initial mass of the…

Dynamical Systems · Mathematics 2023-06-05 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette

In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a…

Analysis of PDEs · Mathematics 2025-02-11 Marcelo Bongarti , Christian Parkinson , Weinan Wang

Two simple agent based models are often employed in epidemic studies: the susceptible-infected (SI) and the susceptible-infected-susceptible (SIS). Both models describe the time evolution of infectious diseases in networks in which vertices…

The SIR model is a classical model characterizing the spreading of infectious diseases. This model describes the time-dependent quantity changes among Susceptible, Infectious, and Recovered groups. By introducing space-depend effects such…

Quantitative Methods · Quantitative Biology 2024-09-18 Md Abu Talha , Yongjia Xu , Shan Zhao , Weihua Geng

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

Populations and Evolution · Quantitative Biology 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

In a metapopulation network, infectious diseases spread widely because of the travel of individuals. In the present study, we consider a modified metapopulation Susceptible-Infected-Removed (SIR) model with a latent period, which we call…

Physics and Society · Physics 2017-08-02 Kazue Kudo , Kanako Mizuno

Identifiability is the property in mathematical modelling that determines if model parameters can be uniquely estimated from data. For infectious disease models, failure to ensure identifiability can lead to misleading parameter estimates…

Methodology · Statistics 2025-06-10 Fanny Bergström , Martina Favero , Tom Britton

There is increasing evidence that one of the most difficult problems in trying to control the ongoing COVID-19 epidemic is the presence of a large cohort of asymptomatic infectives. We develop a SIR-type model taking into account the…

Populations and Evolution · Quantitative Biology 2020-06-29 Giuseppe Gaeta

This paper is devoted to the study of a stochastic epidemiological model which is a variant of the SIR model to which we add an extra factor in the transition rate from susceptible to infected accounting for the inflow of infection due to…

Analysis of PDEs · Mathematics 2021-06-29 Gadi Fibich , Samuel Nordmann

We propose an observer for a SIR epidemic model. The observer is then uplifted into a predictor to compensate for time delays in the input and the output. Tuning criteria are given for tuning gains of the predictor, while the…

Systems and Control · Electrical Eng. & Systems 2021-08-05 Sabine Mondié , Fernando Castaños

Stochasticity and spatial heterogeneity are of great interest recently in studying the spread of an infectious disease. The presented method solves an inverse problem to discover the effectively decisive topology of a heterogeneous network…

Artificial Intelligence · Computer Science 2015-03-13 Yoshiharu Maeno

We study the diffusion of epidemics on networks that are partitioned into local communities. The gross structure of hierarchical networks of this kind can be described by a quotient graph. The rationale of this approach is that individuals…

Social and Information Networks · Computer Science 2016-01-19 Stefano Bonaccorsi , Stefania Ottaviano , Delio Mugnolo , Francesco De Pellegrini

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

Methodology · Statistics 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu