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Deep generative models often perform poorly in real-world applications due to the heterogeneity of natural data sets. Heterogeneity arises from data containing different types of features (categorical, ordinal, continuous, etc.) and…

Machine Learning · Computer Science 2020-06-23 Chao Ma , Sebastian Tschiatschek , José Miguel Hernández-Lobato , Richard Turner , Cheng Zhang

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu

There is a warning light for the loss of plant habitats worldwide that entails concerted efforts to conserve plant biodiversity. Thus, plant species classification is of crucial importance to address this environmental challenge. In recent…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Boi M. Quach , Dinh V. Cuong , Nhung Pham , Dang Huynh , Binh T. Nguyen

Materials discovery requires navigating vast chemical and structural spaces while satisfying multiple, often conflicting, objectives. We present LLM-guided Evolution for MAterials discovery (LLEMA), a unified framework that couples the…

Machine Learning · Computer Science 2026-03-06 Nikhil Abhyankar , Sanchit Kabra , Saaketh Desai , Chandan K. Reddy

Herbarium contains treasures of millions of specimens which have been preserved for several years for scientific studies. To speed up more scientific discoveries, a digitization of these specimens is currently on going to facilitate easy…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Burhan Rashid Hussein , Owais Ahmed Malik , Wee-Hong Ong , Johan Willem Frederik Slik

Herbaria worldwide are housing a treasure of 100s of millions of herbarium specimens, which are increasingly being digitized in recent years and thereby made more easily accessible to the scientific community. At the same time, deep…

Populations and Evolution · Quantitative Biology 2018-03-22 Sohaib Younis , Claus Weiland , Robert Hoehndorf , Stefan Dressler , Thomas Hickler , Bernhard Seeger , Marco Schmidt

Specimen-associated biodiversity data are crucial for biological, environmental, and conservation sciences. A rate shift is needed to extract data from specimen images efficiently, moving beyond human-mediated transcription. We developed…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Robert Turnbull , Emily Fitzgerald , Karen Thompson , Joanne L. Birch

In causal inference, estimating Heterogeneous Treatment Effects (HTEs) from observational data is critical for understanding how different subgroups respond to treatments, with broad applications such as precision medicine and targeted…

Human-Computer Interaction · Computer Science 2024-08-13 Jiehui Zhou , Xumeng Wang , Kam-Kwai Wong , Wei Zhang , Xingyu Liu , Juntian Zhang , Minfeng Zhu , Wei Chen

Plants are fundamentally important to life. Key research areas in plant science include plant species identification, weed classification using hyper spectral images, monitoring plant health and tracing leaf growth, and the semantic…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 K. K. Thyagharajan , I. Kiruba Raji

Researchers in the humanities are among the many who are now exploring the world of big data. They have begun to use programming languages like Python or R and their corresponding libraries to manipulate large data sets and discover brand…

Software Engineering · Computer Science 2020-07-30 Dewi Yokelson

Background: Recently, mixed carbon-helium beams were proposed for range verification in carbon ion therapy: Helium, with three times the range of carbon, serves as an on-line range probe, and is mixed into a therapeutic carbon beam.…

Medical Physics · Physics 2025-12-17 Jennifer J. Hardt , Alexander A. Pryanichnikov , Oliver Jäkel , Joao Seco , Niklas Wahl

Cell-based, mathematical modeling of collective cell behavior has become a prominent tool in developmental biology. Cell-based models represent individual cells as single particles or as sets of interconnected particles, and predict the…

Cell Behavior · Quantitative Biology 2019-03-12 Henri B. Wolff , Lance A. Davidson , Roeland M. H. Merks

The technological advancements of the modern era have enabled the collection of huge amounts of data in science and beyond. Extracting useful information from such massive datasets is an ongoing challenge as traditional data visualization…

Applications · Statistics 2017-01-30 Rebecca L Barter , Bin Yu

Process-based models (PBMs) and deep learning (DL) are two key approaches in agricultural modelling, each offering distinct advantages and limitations. PBMs provide mechanistic insights based on physical and biological principles, ensuring…

Ecologists have long suspected that species are more likely to interact if their traits match in a particular way. For example, a pollination interaction may be more likely if the proportions of a bee's tongue fit a plant's flower shape.…

Populations and Evolution · Quantitative Biology 2019-11-05 Maximilian Pichler , Virginie Boreux , Alexandra-Maria Klein , Matthias Schleuning , Florian Hartig

We are living in the big data age: An ever increasing amount of data is being produced through data acquisition and computer simulations. While large scale analysis and simulations have received significant attention for cloud and…

Graphics · Computer Science 2019-02-26 Stefan Eilemann

Drug discovery aims at designing novel molecules with specific desired properties for clinical trials. Over past decades, drug discovery and development have been a costly and time consuming process. Driven by big chemical data and AI, deep…

Machine Learning · Computer Science 2020-07-22 Karan Yang , Chengxi Zang , Fei Wang

One of the important questions in biological evolution is to know if certain changes along protein coding genes have contributed to the adaptation of species. This problem is known to be biologically complex and computationally very…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-03-15 Sébastien Moretti , Riccardo Murri , Sergio Maffioletti , Arnold Kuzniar , Briséïs Castella , Nicolas Salamin , Marc Robinson-Rechavi , Heinz Stockinger

Plant traits such as leaf carbon content and leaf mass are essential variables in the study of biodiversity and climate change. However, conventional field sampling cannot feasibly cover trait variation at ecologically meaningful spatial…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Eya Cherif , Arthur Ouaknine , Luke A. Brown , Phuong D. Dao , Kyle R. Kovach , Bing Lu , Daniel Mederer , Hannes Feilhauer , Teja Kattenborn , David Rolnick

Existing plant disease classification models have achieved remarkable performance in recognizing in-laboratory diseased images. However, their performance often significantly degrades in classifying in-the-wild images. Furthermore, we…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Tianqi Wei , Zhi Chen , Zi Huang , Xin Yu