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The effective visualization of genomic data is crucial for exploring and interpreting complex relationships within and across genes and genomes. Despite advances in developing dedicated bioinformatics software, common visualization tools…

Genomics · Quantitative Biology 2024-11-22 Thomas Hackl , Markus Ankenbrand , Bart van Adrichem , David Wilkins , Kristina Haslinger

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

Machine Learning · Computer Science 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Data visualization is a fundamental tool in genomics research, enabling the exploration, interpretation, and communication of complex genomic features. While machine learning models show promise for transforming data into insightful…

In modern biomedical research, it is ubiquitous to have multiple data sets measured on the same set of samples from different views (i.e., multi-view data). For example, in genetic studies, multiple genomic data sets at different molecular…

Methodology · Statistics 2017-03-20 Gen Li , Sungkyu Jung

Analyzing large complex image collections in domains like forensics, accident investigation, or social media analysis involves interpreting intricate, overlapping relationships among images. Traditional clustering and classification methods…

Graphics · Computer Science 2025-10-24 Floris Gisolf , Zeno J. M. H. Geradts , Marcel Worring

The advent of plant phenomics, coupled with the wealth of genotypic data generated by next-generation sequencing technologies, provides exciting new resources for investigations into and improvement of complex traits. However, these new…

Genomics · Quantitative Biology 2019-04-30 Gota Morota , Diego Jarquin , Malachy T. Campbell , Hiroyoshi Iwata

Modern DNA sequencing technologies enable geneticists to rapidly identify genetic variation among many human genomes. However, isolating the minority of variants underlying disease remains an important, yet formidable challenge for medical…

Genomics · Quantitative Biology 2015-06-15 Uma Paila , Brad Chapman , Rory Kirchner , Aaron Quinlan

Arabidopsis thaliana is an important model organism for understanding the genetics and molecular biology of plants. Its highly selfing nature, together with other important features, such as small size, short generation time, small genome…

Quantitative Methods · Quantitative Biology 2013-08-12 Ümit Seren , Bjarni J. Vilhjálmsson , Matthew W. Horton , Dazhe Meng , Petar Forai , Yu S. Huang , Quan Long , Vincent Segura , Magnus Nordborg

Integrating AI in healthcare can greatly improve patient care and system efficiency. However, the lack of explainability in AI systems (XAI) hinders their clinical adoption, especially in multimodal settings that use increasingly complex…

Machine Learning · Computer Science 2025-04-18 Laura Wenderoth , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Breeding by introgressive hybridization is a pivotal strategy to broaden the genetic basis of crops. Usually, the desired traits are monitored in consecutive crossing generations by marker-assisted selection, but their analyses fail in…

We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enough to scale the analysis to population level. There currently…

The problem of inferring unknown graph edges from numerical data at a graph's nodes appears in many forms across machine learning. We study a version of this problem that arises in the field of \emph{landscape genetics}, where genetic…

Machine Learning · Computer Science 2021-03-11 Prathamesh Dharangutte , Christopher Musco

A bottleneck in any evolutionary art system is aesthetic evaluation. Many different methods have been proposed to automate the evaluation of aesthetics, including measures of symmetry, coherence, complexity, contrast and grouping. The…

Neural and Evolutionary Computing · Computer Science 2020-04-16 Jon McCormack , Andy Lomas

Graph layout is the process of creating a visual representation of a graph through a node-link diagram. Node-attribute graphs have additional data stored on the nodes which describe certain properties of the nodes called attributes. Typical…

Graphics · Computer Science 2017-12-18 Helen Gibson , Paul Vickers

Interactive data visualization is a major part of modern exploratory data analysis, with web-based technologies enabling a rich ecosystem of both specialized and general tools. However, current visualization tools often lack support for…

Human-Computer Interaction · Computer Science 2025-08-14 Jan Simson

Computing haplotypes from sequencing data, i.e. haplotype assembly, is an important component of molecular and population genetics problems, including interpreting the effects of genetic variation on complex traits and reconstructing…

Genomics · Quantitative Biology 2026-03-12 Marjan Hosseini , Ella Veiner , Thomas Bergendahl , Tala Yasenpoor , Zane Smith , Margaret Staton , Derek Aguiar

More advanced visualization tools are needed to assist with the analyses and interpretation of human metabolomics data, which are rapidly increasing in quantity and complexity. Using a dataset of several hundred bioactive lipid metabolites…

This paper describes an ongoing multi-scale visual analytics approach for exploring and analyzing biomedical knowledge at scale.We utilize global and local views, hierarchical and flow-based graph layouts, multi-faceted search, neighborhood…

Human-Computer Interaction · Computer Science 2021-10-22 Fahd Husain , Rosa Romero-Gomez , Emily Kuang , Dario Segura , Adamo Carolli , Lai Chung Liu , Manfred Cheung , Yohann Paris

We describe a new visualization tool, dubbed HCMapper, that visually helps to compare a pair of dendrograms computed on the same dataset by displaying multiscale partition-based layered structures. The dendrograms are obtained by…

Human-Computer Interaction · Computer Science 2016-02-23 Gautier Marti , Philippe Donnat , Frank Nielsen , Philippe Very

In this work, an evolutionary art project is presented where images are approximated by transparent, overlapping and geometric shapes of different types, e.g., polygons, circles, lines. Genotypes representing features and order of the…