Related papers: Simple connectome inference from partial correlati…
There is increasing interest in learning a set of small outcome-relevant subgraphs in network-predictor regression. The extracted signal subgraphs can greatly improve the interpretation of the association between the network predictor and…
Link prediction is one of the fundamental problems in network analysis. In many applications, notably in genetics, a partially observed network may not contain any negative examples of absent edges, which creates a difficulty for many…
One of the primary goals of systems neuroscience is to relate the structure of neural circuits to their function, yet patterns of connectivity are difficult to establish when recording from large populations in behaving organisms. Many…
In recent years, it has become common practice in neuroscience to use networks to summarize relational information in a set of measurements, typically assumed to be reflective of either functional or structural relationships between regions…
Miniaturized calcium imaging is an emerging neural recording technique that has been widely used for monitoring neural activity on a large scale at a specific brain region of rats or mice. Most existing calcium-image analysis pipelines…
This work presents an unsupervised and semi-automatic image segmentation approach where we formulate the segmentation as a inference problem based on unary and pairwise assignment probabilities computed using low-level image cues. The…
The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…
Electron microscopic connectomics is an ambitious research direction with the goal of studying comprehensive brain connectivity maps by using high-throughput, nano-scale microscopy. One of the main challenges in connectomics research is…
We present an inference method utilizing artificial neural networks for parameter estimation of a quantum probe monitored through a single continuous measurement. Unlike existing approaches focusing on the diffusive signals generated by…
Inferring the connectivity of neural circuits from incomplete observations is a fundamental challenge in neuroscience. We present a covariance-based method for estimating the weight matrix of a recurrent neural network from sparse, partial…
Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…
Inferring a binary connectivity graph from resting-state fMRI data for a single subject requires making several methodological choices and assumptions that can significantly affect the results. In this study, we investigate the robustness…
The anatomical structure of the brain can be observed via non-invasive techniques such as diffusion imaging. However, these are imperfect because they miss connections that are actually known to exist, especially long range…
The field of connectomics faces unprecedented "big data" challenges. To reconstruct neuronal connectivity, automated pixel-level segmentation is required for petabytes of streaming electron microscopy data. Existing algorithms provide…
In this paper we study a linear inverse problem with a biological interpretation, which is modeled by a Fredholm integral equation of the first kind. When the kernel in the Fredholm equation is represented by step func- tions, we obtain…
Brain connectivity analysis is now at the foreground of neuroscience research. A connectivity network is characterized by a graph, where nodes represent neural elements such as neurons and brain regions, and links represent statistical…
Researchers in the field of connectomics are working to reconstruct a map of neural connections in the brain in order to understand at a fundamental level how the brain processes information. Constructing this wiring diagram is done by…
There is no consensus on how to construct structural brain networks from diffusion MRI. How variations in pre-processing steps affect network reliability and its ability to distinguish subjects remains opaque. In this work, we address this…
In this work, we study the extent to which structural connectomes and topological derivative measures are unique to individual changes within human brains. To do so, we classify structural connectome pairs from two large longitudinal…
We give an information-theoretic interpretation of Canonical Correlation Analysis (CCA) via (relaxed) Wyner's common information. CCA permits to extract from two high-dimensional data sets low-dimensional descriptions (features) that…