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The main result of this thesis is the development of a novel connectivity estimation method, called Total Spiking Probability Edges (TSPE). Based on cross-correlation and edge filtering at different time scales this method is proposed and…

Signal Processing · Electrical Eng. & Systems 2020-05-15 Stefano De Blasi

Multi-frame detection algorithms can effectively utilize the correlation between consecutive echoes to improve the detection performance of weak targets. Existing efficient multi-frame detection algorithms are typically based on three…

Signal Processing · Electrical Eng. & Systems 2025-12-16 Zhihao Lin , Chang Gao , Junkun Yan , Qingfu Zhang , Bo Chen , Hongwei Liu

Predicting protein-protein interactions from sequences is an important goal of computational biology. Various sources of information can be used to this end. Starting from the sequences of two interacting protein families, one can use…

Biomolecules · Quantitative Biology 2023-04-26 Carlos A. Gandarilla-Perez , Sergio Pinilla , Anne-Florence Bitbol , Martin Weigt

Quantum imaging has a potential of enhancing precision of the object reconstruction by using quantum correlations of the imaging field. This is especially important for imaging requiring low-intensity fields up to the level of few-photons.…

The assessment of brain fingerprints has emerged in the recent years as an important tool to study individual differences and to infer quality of neuroimaging datasets. Studies so far have mainly focused on connectivity fingerprints between…

Neurons and Cognition · Quantitative Biology 2021-01-13 Uttara Tipnis , Kausar Abbas , Elizabeth Tran , Enrico Amico , Li Shen , Alan D. Kaplan , Joaquín Goñi

Predicting the evolution of the brain network, also called connectome, by foreseeing changes in the connectivity weights linking pairs of anatomical regions makes it possible to spot connectivity-related neurological disorders in earlier…

Machine Learning · Computer Science 2021-09-17 Şeymanur Aktı , Doğay Kamar , Özgür Anıl Özlü , Ihsan Soydemir , Muhammet Akcan , Abdullah Kul , Islem Rekik

Recently, there has been extensive research on the capabilities of biologically plausible algorithms. In this work, we show how one of such algorithms, called predictive coding, is able to perform causal inference tasks. First, we show how…

Machine Learning · Computer Science 2024-06-04 Tommaso Salvatori , Luca Pinchetti , Amine M'Charrak , Beren Millidge , Thomas Lukasiewicz

Data-driven discovery of dynamics in biological systems allows for better observation and characterization of processes, such as calcium signaling in cell culture. Recent advancements in techniques allow the exploration of previously…

Quantitative Methods · Quantitative Biology 2025-05-28 Aurora Poggi , Giuseppe Alessio D'Inverno , Hjalmar Brismar , Ozan Öktem , Matthieu Barreau , Kateryna Morozovska

Glaucoma is a disease in which the optic nerve is chronically damaged by the elevation of the intra-ocular pressure, resulting in visual field defect. Therefore, it is important to monitor and treat suspected patients before they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-05 Tae Joon Jun , Dohyeun Kim , Hoang Minh Nguyen , Daeyoung Kim , Youngsub Eom

Developing automated and semi-automated solutions for reconstructing wiring diagrams of the brain from electron micrographs is important for advancing the field of connectomics. While the ultimate goal is to generate a graph of neuron…

Computer Vision and Pattern Recognition · Computer Science 2016-08-09 William Gray Roncal , Colin Lea , Akira Baruah , Gregory D. Hager

This paper presents a novel graph-based kernel learning approach for connectome analysis. Specifically, we demonstrate how to leverage the naturally available structure within the graph representation to encode prior knowledge in the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Jun Yu , Zhaoming Kong , Aditya Kendre , Hao Peng , Carl Yang , Lichao Sun , Alex Leow , Lifang He

Statistical similarities between neuronal spike trains could reveal significant information on complex underlying processing. In general, the similarity between synchronous spike trains is somewhat easy to identify. However, the similar…

Neurons and Cognition · Quantitative Biology 2021-03-16 Sathish Ande , Jayanth R Regatti , Neha Pandey , Ajith Karunarathne , Lopamudra Giri , Soumya Jana

Recent remarkable advances in the experimental techniques have provided a background for inferring neuronal couplings from point process data that includes a great number of neurons. Here, we propose a systematic procedure for pre- and…

Disordered Systems and Neural Networks · Physics 2020-07-08 Yu Terada , Tomoyuki Obuchi , Takuya Isomura , Yoshiyuki Kabashima

In statistical connectomics, the quantitative study of brain networks, estimating the mean of a population of graphs based on a sample is a core problem. Often, this problem is especially difficult because the sample or cohort size is…

In an inhomogeneously illuminated photoacoustic image, important information like vascular geometry is not readily available when only the initial pressure is reconstructed. To obtain the desired information, algorithms for image…

Image and Video Processing · Electrical Eng. & Systems 2019-06-19 Yoeri E. Boink , Srirang Manohar , Christoph Brune

Connected component analysis (CCA) has been heavily used to label binary images and classify segments. However, it has not been well-exploited to segment multi-valued natural images. This work proposes a novel multi-value segmentation…

Computer Vision and Pattern Recognition · Computer Science 2014-02-12 Dibyendu Mukherjee

Brain disorders are an umbrella term for a group of neurological and psychiatric conditions that have a major effect on thinking, feeling, and acting. These conditions encompass a wide range of conditions. The illnesses in question pose…

Neurons and Cognition · Quantitative Biology 2025-11-11 Aniruddha Saha , Soujanya Hazra , Sanjay Ghosh

One of the crucial questions in neuroscience is how a rich functional repertoire of brain states relates to its underlying structural organization. How to study the associations between these structural and functional layers is an open…

Neurons and Cognition · Quantitative Biology 2018-02-22 Enrico Amico , Joaquín Goñi

Functional connectomes derived from functional magnetic resonance imaging have long been used to understand the functional organization of the brain. Nevertheless, a connectome is intrinsically linked to the atlas used to create it. In…

Neurons and Cognition · Quantitative Biology 2021-07-06 Javid Dadashkarimi , Amin Karbasi , Dustin Scheinost

Coronary artery stenosis is a critical health risk, and its precise identification in Coronary Angiography (CAG) can significantly aid medical practitioners in accurately evaluating the severity of a patient's condition. The complexity of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 In Kyu Lee , Junsup Shin , Yong-Hee Lee , Jonghoe Ku , Hyun-Woo Kim