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Objective evaluation of new and improved methods for PET imaging requires access to images with ground truth, as can be obtained through simulation studies. However, for these studies to be clinically relevant, it is important that the…

In ultrasound imaging the appearance of homogeneous regions of tissue is subject to speckle, which for certain applications can make the detection of tissue irregularities difficult. To cope with this, it is common practice to apply speckle…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Rüdiger Göbl , Christoph Hennersperger , Nassir Navab

Optical coherence tomography (OCT) is a popular modality in ophthalmology and is also used intravascularly. Our interest in this work is OCT in the context of airway abnormalities in infants and children where the high resolution of OCT and…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Yining Jiao , Amy Oldenburg , Yinghan Xu , Srikamal Soundararajan , Carlton Zdanski , Julia Kimbell , Marc Niethammer

Spectral computed tomography (CT) has recently emerged as an advanced version of medical CT and significantly improves conventional (single-energy) CT. Spectral CT has two main forms: dual-energy computed tomography (DECT) and…

In this paper, we consider the problem of estimating the internal displacement field of an object which is being subjected to a deformation, from Optical Coherence Tomography (OCT) images before and after compression. For the estimation of…

Numerical Analysis · Mathematics 2020-12-30 Ekaterina Sherina , Lisa Krainz , Simon Hubmer , Wolfgang Drexler , Otmar Scherzer

We demonstrate in a {\it proof-of-concept} experiment spectral-domain optical coherence tomography where steering of the optical beam that probes the sample in a transverse scan does not make use of any mechanical element. Steering is done…

Optics · Physics 2023-12-15 Daniel F. Urrego , Gerard J. Machado , Juan P. Torres

Optical coherence tomography (OCT) is a label-free, non-invasive 3D imaging tool widely used in both biological research and clinical diagnosis. Current OCT modalities can only visualize specimen tomography without chemical information.…

X-ray speckles have been used for a wide variety of experiments, ranging from imaging (and tomography), wavefront sensing, spatial coherence measurements all the way to x-ray photon correlation spectroscopy (XPCS) and ptychography. In the…

Medical Physics · Physics 2024-04-19 Rafael Celestre , Laurene Quenot , Christopher Ninham , Emmanuel Brun , Luca Fardin

Eye movements, blinking and other motion during the acquisition of optical coherence tomography (OCT) can lead to artifacts, when processed to OCT angiography (OCTA) images. Affected scans emerge as high intensity (white) or missing (black)…

Image and Video Processing · Electrical Eng. & Systems 2020-01-09 Julian Hossbach , Lennart Husvogt , Martin F. Kraus , James G. Fujimoto , Andreas K. Maier

Optical Coherence Tomography (OCT) image denoising is a fundamental problem as OCT images suffer from multiplicative speckle noise, resulting in poor visibility of retinal layers. The traditional denoising methods consider specific…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 Arka Saha , Sourya Sengupta

Optical coherence tomography (OCT) is a prevalent imaging technique for retina. However, it is affected by multiplicative speckle noise that can degrade the visibility of essential anatomical structures, including blood vessels and tissue…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Dewei Hu , Joseph D. Malone , Yigit Atay , Yuankai K. Tao , Ipek Oguz

The paper presents an analysis of the possible spectra manipulation and its consequence for the specific application of XCT. The focus was on the modification of the registered spectra dominantly by the sewing/stitching method. A model…

Atomic Physics · Physics 2024-06-04 A. J. Arikkat , K. A. Janulewicz , C. M. Kim , P. Wachulak

Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Mohammad Rahimzadeh , Mahmoud Reza Mohammadi

In this paper, we present a method for speckle pattern design using deep learning. The speckle patterns possess unique features after experiencing convolutions in Speckle-Net, our well-designed framework for speckle pattern generation. We…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Xiaoyu Nie , Haotian Song , Wenhan Ren , Xingchen Zhao , Zhedong Zhang , Tao Peng , Marlan O. Scully

With the introduction of spectral-domain optical coherence tomography (OCT), resulting in a significant increase in acquisition speed, the fast and accurate segmentation of 3-D OCT scans has become evermore important. This paper presents a…

Computer Vision and Pattern Recognition · Computer Science 2014-04-01 Fabian Rathke , Stefan Schmidt , Christoph Schnörr

Recent advancements in medical image analysis have led to the development of highly specialized models tailored to specific clinical tasks. These models have demonstrated exceptional performance and remain a crucial research direction. Yet,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Alessio Negrini , Simon Reiß

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Pooya Khosravi , Kun Han , Anthony T. Wu , Arghavan Rezvani , Zexin Feng , Xiaohui Xie

Current spectroscopic optical coherence tomography (OCT) methods rely on a posteriori numerical calculation. We present an alternative for accessing optically the spectroscopic information in OCT, i.e. without any post-processing, by using…

Incoherently illuminated or luminescent objects give rise to a low-contrast speckle-like pattern when observed through a thin diffusive medium, as such a medium effectively convolves their shape with a speckle-like point spread function…

We present a general theory of optical coherence tomography (OCT), which synthesizes the fundamental concepts and implementations of OCT under a common 3D k-space framework. At the heart of this analysis is the Fourier diffraction theorem,…

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