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Due to its noninvasive character, optical coherence tomography (OCT) has become a popular diagnostic method in clinical settings. However, the low-coherence interferometric imaging procedure is inevitably contaminated by heavy speckle…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Yongqiang Huang , Wenjun Xia , Zexin Lu , Yan Liu , Hu Chen , Jiliu Zhou , Leyuan Fang , Yi Zhang

Spectral domain optical coherence tomography (OCT) offers high resolution multidimensional imaging, but generally suffers from defocussing, intensity falloff and shot noise, causing artifacts and image degradation along the imaging depth.…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Jonathan H. Mason , Yvonne Reinwald , Ying Yang , Sarah Waters , Alicia El Haj , Pierre O. Bagnaninchi

Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Dewei Hu , Yuankai K. Tao , Ipek Oguz

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

Optical Coherence Tomography(OCT) is a non-invasive technique capturing cross-sectional area of the retina in micro-meter resolutions. It has been widely used as a auxiliary imaging reference to detect eye-related pathology and predict…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Shuo Chen , Da Ma , Sieun Lee , Timothy T. L. Yu , Gavin Xu , Donghuan Lu , Karteek Popuri , Myeong Jin Ju , Marinko V. Sarunic , Mirza Faisal Beg

Optical images of transparent three-dimensional objects can be different from a replica of the object's cross section in the image plane due to refraction at the surface or in the body of the object. Simulations of the object's image are…

Conventional Fourier-domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into wavenumber (k) domain to extract the depth profile. This either necessitates additional hardware resources or amplifies the existing…

Optics · Physics 2025-09-24 Maryam Viqar , Erdem Sahin , Elena Stoykova , Violeta Madjarova

The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve…

We demonstrate a deep-learning-based scatterer density estimator (SDE) that processes local speckle patterns of optical coherence tomography (OCT) images and estimates the scatterer density behind each speckle pattern. The SDE is trained…

In vivo application of dynamic optical coherence tomography (DOCT) is hindered by bulk motion of the sample. We demonstrate DOCT imaging of \invivo human skin by adopting a sample-fixation attachment to suppress bulk motion and a subsequent…

Displacement estimation in optical coherence tomography (OCT) imaging is relevant for several potential applications, e.g. for optical coherence elastography (OCE) for corneal biomechanical characterization. Larger displacements may be…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Hossein Khodadadi , Orcun Goksel , Sabine Kling

The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here…

Imaging airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using…

Speckle photography can be used to monitor deformations of solid surfaces. The measuring characteristics, such as range or lateral resolution depend heavily on the optical recording and illumination set-up. This paper shows how, by the…

Optics · Physics 2014-01-30 Jose M. Diazdelacruz

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital…

Simulating optical tactile sensors presents significant challenges due to their high deformability and intricate optical properties. To address these issues and enable a physically accurate simulation, we propose DOT-Sim: Differentiable…

Robotics · Computer Science 2026-05-01 Yang You , Won Kyung Do , Aiden Swann , Rika Antonova , Monroe Kennedy , Leonidas Guibas

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and…

Medical Physics · Physics 2019-07-02 Cerine Lal , Hrebesh M Subhash , Sergey Alexandrov , Martin J Leahy

Purpose. Localizing structures and estimating the motion of a specific target region are common problems for navigation during surgical interventions. Optical coherence tomography (OCT) is an imaging modality with a high spatial and…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Marcel Bengs , Nils Gessert , Matthias Schlüter , Alexander Schlaefer

Quantitative tissue information, like the light scattering properties, is considered as a key player in the detection of cancerous cells in medical diagnosis. A promising method to obtain these data is optical coherence tomography (OCT). In…

Numerical Analysis · Mathematics 2023-06-21 Leopold Veselka , Peter Elbau , Leonidas Mindrinos , Lisa Krainz , Wolfgang Drexler