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DNA sequencing is becoming increasingly commonplace, both in medical and direct-to-consumer settings. To promote discovery, collected genomic data is often de-identified and shared, either in public repositories, such as OpenSNP, or with…

Machine Learning · Computer Science 2022-12-21 Rajagopal Venkatesaramani , Bradley A. Malin , Yevgeniy Vorobeychik

Quantum computing often requires classical data to be supplied to execution environments that may not be fully trusted or isolated. While encryption protects data at rest and in transit, it provides limited protection once computation…

Cryptography and Security · Computer Science 2026-03-19 Amal Raj , Vivek Balachandran

Recent advances in DNA sequencing technologies have put ubiquitous availability of fully sequenced human genomes within reach. It is no longer hard to imagine the day when everyone will have the means to obtain and store one's own DNA…

Cryptography and Security · Computer Science 2015-03-19 Pierre Baldi , Roberta Baronio , Emiliano De Cristofaro , Paolo Gasti , Gene Tsudik

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…

Cryptography and Security · Computer Science 2022-02-11 Sara Jafarbeiki , Raj Gaire , Amin Sakzad , Shabnam Kasra Kermanshahi , Ron Steinfeld

In the post-genomic era, large-scale personal DNA sequences are produced and collected for genetic medical diagnoses and new drug discovery, which, however, simultaneously poses serious challenges to the protection of personal genomic…

Cryptography and Security · Computer Science 2017-08-10 Shibiao Wan , Man-Wai Mak , Sun-Yuan Kung

Motivation: Researchers need a rich trove of genomic datasets that they can leverage to gain a better understanding of the genetic basis of the human genome and identify associations between phenotypes and specific parts of DNA. However,…

Cryptography and Security · Computer Science 2021-06-10 Nour Almadhoun Alserr , Gulce Kale , Onur Mutlu , Oznur Tastan , Erman Ayday

The paper studies how to release data about a critical infrastructure network (e.g., the power network or a transportation network) without disclosing sensitive information that can be exploited by malevolent agents, while preserving the…

Cryptography and Security · Computer Science 2020-04-20 Ferdinando Fioretto , Terrence W. K. Mak , Pascal Van Hentenryck

When classical or quantum information is broadcast to separate receivers, there exist codes that encrypt the encoded data such that the receivers cannot recover it when performing local operations and classical communication, but they can…

Quantum Physics · Physics 2016-05-31 Cosmo Lupo , Mark M. Wilde , Seth Lloyd

As machine learning becomes a practice and commodity, numerous cloud-based services and frameworks are provided to help customers develop and deploy machine learning applications. While it is prevalent to outsource model training and…

Cryptography and Security · Computer Science 2018-07-16 Tianwei Zhang , Zecheng He , Ruby B. Lee

Minimizing privacy leakage while ensuring data utility is a critical problem to data holders in a privacy-preserving data publishing task. Most prior research concerns only with one type of data and resorts to a single obscuring method,…

Cryptography and Security · Computer Science 2021-12-16 Xiao Han , Yuncong Yang , Junjie Wu

DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

Information Theory · Computer Science 2025-04-22 Ruiying Cao , Xin Chen

The lack of data democratization and information leakage from trained models hinder the development and acceptance of robust deep learning-based healthcare solutions. This paper argues that irreversible data encoding can provide an…

Machine Learning · Computer Science 2023-05-08 Anshul Thakur , Tingting Zhu , Vinayak Abrol , Jacob Armstrong , Yujiang Wang , David A. Clifton

We extend covert communication to the quantum regime by showing that covert quantum communication is possible over optical channels with noise arising either from the environment or from the sender's lab. In particular, we show that…

Quantum Physics · Physics 2016-12-21 Juan Miguel Arrazola , Valerio Scarani

Balancing privacy and predictive utility remains a central challenge for machine learning in healthcare. In this paper, we develop Syfer, a neural obfuscation method to protect against re-identification attacks. Syfer composes trained…

Advances in de novo synthesis of DNA and computational gene design methods make possible the customization of genes by direct manipulation of features such as codon bias and mRNA secondary structure. Codon context is another feature…

Data Structures and Algorithms · Computer Science 2015-08-17 Dimitris Papamichail , Hongmei Liu , Vitor Machado , Nathan Gould , J. Robert Coleman , Georgios Papamichail

DNA fingerprinting is a cornerstone for human identification in forensics, where the sequence of highly polymorphic short tandem repeats (STRs) from an individual is compared against a DNA database. This presents significant privacy risks…

Cryptography and Security · Computer Science 2021-03-30 Taeho Jung , Ryan Karl , Geoffrey H. Siwo

Motivation: Next Generation Sequencing technologies revolutionized many fields in biology by enabling the fast and cheap sequencing of large amounts of genomic data. The ever increasing sequencing capacities enabled by current sequencing…

Genomics · Quantitative Biology 2012-07-24 Himanshu Asnani , Dinesh Bharadia , Mainak Chowdhury , Idoia Ochoa , Itai Sharon , Tsachy Weissman

Typical personal medical data contains sensitive information about individuals. Storing or sharing the personal medical data is thus often risky. For example, a short DNA sequence can provide information that can not only identify an…

Cryptography and Security · Computer Science 2019-02-01 Ho Bae , Dahuin Jung , Sungroh Yoon

Data compression plays an important role to deal with high volumes of DNA sequences in the field of Bioinformatics. Again data compression techniques directly affect the alignment of DNA sequences. So the time needed to decompress a…

Computational Engineering, Finance, and Science · Computer Science 2012-11-13 Subhankar Roy , Sunirmal Khatua , Sudipta Roy , Samir K. Bandyopadhyay

Balancing the needs of data privacy and predictive utility is a central challenge for machine learning in healthcare. In particular, privacy concerns have led to a dearth of public datasets, complicated the construction of multi-hospital…