Related papers: Functional optimization of the arterial network
We reveal that under moderate shear stress (of the order of 0.1 Pa) red blood cells present an oscillation of their inclination (swinging) superimposed to the long-observed steady tanktreading (TT) motion. A model based on a fluid ellipsoid…
We model a system of networking agents that seek to optimize their centrality in the network while keeping their cost, the number of connections they are participating in, low. Unlike other game-theory based models for network evolution,…
Coronary angiography is considered to be a safe tool for the evaluation of coronary artery disease and perform in approximately 12 million patients each year worldwide. [1] In most cases, angiograms are manually analyzed by a cardiologist.…
The automated analysis of flow cytometry measurements is an active research field. We introduce a new algorithm, referred to as CytOpT, using regularized optimal transport to directly estimate the different cell population proportions from…
There has been a long debate on how new levels of organization have evolved. It might seem unlikely, as cooperation must prevail over competition. One well-studied example is the emergence of autocatalytic sets, which seem to be a…
Although species longevity is subject to a diverse range of selective forces, the mortality curves of a wide variety of organisms are rather similar. We argue that aging and its universal characteristics may have evolved by means of a…
Optimizing the energy efficiency of driving processes provides valuable insights into the underlying physics and is of crucial importance for numerous applications, from biological processes to the design of machines and robots. Knowledge…
In order to survive, reproduce and (in multicellular organisms) differentiate, cells must control the concentrations of the myriad different proteins that are encoded in the genome. The precision of this control is limited by the inevitable…
Estimating clinically-relevant vascular features following vessel segmentation is a standard pipeline for retinal vessel analysis, which provides potential ocular biomarkers for both ophthalmic disease and systemic disease. In this work, we…
The brain can be considered as a system that dynamically optimizes the structure of anatomical connections based on the efficiency requirements of functional connectivity. To illustrate the power of this principle in organizing the…
Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…
Network dynamics offers critical insights into the behavior and evolution of complex systems. Here, we focus on the topological dynamics of networks to explore a unique process for reducing the average distance: topological compression. The…
The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…
Strokes are still one of the leading causes for death after heart diseases and cancer in all over the world. Most strokes happen because an artery that carries blood uphill from the heart to the head gets clogged. Most of the time, as with…
The performance of distributed averaging depends heavily on the underlying topology. In various fields, including compressed sensing, multi-party computation, and abstract graph theory, graphs may be expected to be free of short cycles,…
Prestrained elastic networks arise in a number of biological and technological systems ranging from the cytoskeleton of cells to tensegrity structures. To understand the response of such a network as a function of the prestrain, we consider…
Using a stochastic cellular automaton model for urban traffic flow, we study and compare Macroscopic Fundamental Diagrams (MFDs) of arterial road networks governed by different types of adaptive traffic signal systems, under various…
The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…
Shear stress plays an important role in the creation and evolution of atherosclerosis. An key element for in-vivo measurements and extrapolations is the dependence of shear stress on body mass. In the case of a Poiseuille modeling of the…
Controlling the flow and routing of data is a fundamental problem in many distributed networks, including transportation systems, integrated circuits, and the Internet. In the brain, synaptic plasticity rules have been discovered that…