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The increasing number of protein sequences decoded from genomes is opening up new avenues of research on linking protein sequence to function with transformer neural networks. Recent research has shown that the number of known protein…

Machine Learning · Computer Science 2022-06-23 Anowarul Kabir , Amarda Shehu

Learning language of protein sequences, which captures non-local interactions between amino acids close in the spatial structure, is a long-standing bioinformatics challenge, which requires at least context-free grammars. However, complex…

Formal Languages and Automata Theory · Computer Science 2019-03-20 Witold Dyrka , François Coste , Juliette Talibart

Motivation: Proteins are of great significance in living organisms. However, understanding their functions encounters numerous challenges, such as insufficient integration of multimodal information, a large number of training parameters,…

Machine Learning · Computer Science 2025-05-23 Zhicong Wang , Zicheng Ma , Ziqiang Cao , Changlong Zhou , Jun Zhang , Yiqin Gao

Web discussion forums are used by millions of people worldwide to share information belonging to a variety of domains such as automotive vehicles, pets, sports, etc. They typically contain posts that fall into different categories such as…

Computation and Language · Computer Science 2016-04-26 Krish Perumal

Prior methods to text segmentation are mostly at token level. Despite the adequacy, this nature limits their full potential to capture the long-term dependencies among segments. In this work, we propose a novel framework that incrementally…

Computation and Language · Computer Science 2021-04-16 Yangming Li , Lemao Liu , Kaisheng Yao

Keyphrase extraction is the process of automatically selecting a small set of most relevant phrases from a given text. Supervised keyphrase extraction approaches need large amounts of labeled training data and perform poorly outside the…

Computation and Language · Computer Science 2023-01-03 Tim Schopf , Simon Klimek , Florian Matthes

Is protein secondary structure primarily determined by local interactions between residues closely spaced along the amino acid backbone, or by non-local tertiary interactions? To answer this question we have measured the entropy densities…

Biomolecules · Quantitative Biology 2007-05-23 Gavin E. Crooks , Steven E. Brenner

Attention-based deep networks have been successfully applied on textual data in the field of NLP. However, their application on protein sequences poses additional challenges due to the weak semantics of the protein words, unlike the plain…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , Akshay Deepak

We propose an unsupervised method for detecting loanwords i.e., words borrowed from one language into another. While prior work has primarily relied on language-external information to identify loanwords, such approaches can introduce…

Computation and Language · Computer Science 2025-08-26 Promise Dodzi Kpoglu

We propose a new approach to the Chinese word segmentation problem that considers the sentence as an undirected graph, whose nodes are the characters. One can use various techniques to compute the edge weights that measure the connection…

Computation and Language · Computer Science 2018-04-06 Yuanhao Liu , Sheng Yu

Breaking down a document or a conversation into multiple contiguous segments based on its semantic structure is an important and challenging problem in NLP, which can assist many downstream tasks. However, current works on topic…

Computation and Language · Computer Science 2023-10-27 Reshmi Ghosh , Harjeet Singh Kajal , Sharanya Kamath , Dhuri Shrivastava , Samyadeep Basu , Hansi Zeng , Soundararajan Srinivasan

Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of protein sequences, but structure is critical for…

Machine Learning · Computer Science 2019-10-17 Tristan Bepler , Bonnie Berger

To minimize the annotation costs associated with the training of semantic segmentation models, researchers have extensively investigated weakly-supervised segmentation approaches. In the current weakly-supervised segmentation methods, the…

Computer Vision and Pattern Recognition · Computer Science 2019-11-13 Wataru Shimoda , Keiji Yanai

The Automated Protein Structure Analysis (APSA) method is used for the classification of supersecondary structures. Basis for the classification is the encoding of three-dimensional (3D) residue conformations into a 16-letter code (3D-1D…

Quantitative Methods · Quantitative Biology 2008-11-24 Sushilee Ranganathan , Dmitry Izotov , Elfi Kraka , Dieter Cremer

We demonstrate the effectiveness of multilingual learning for unsupervised part-of-speech tagging. The central assumption of our work is that by combining cues from multiple languages, the structure of each becomes more apparent. We…

Computation and Language · Computer Science 2014-01-23 Tahira Naseem , Benjamin Snyder , Jacob Eisenstein , Regina Barzilay

This paper demonstrates that language models are strong structure-based protein designers. We present LM-Design, a generic approach to reprogramming sequence-based protein language models (pLMs), that have learned massive sequential…

Machine Learning · Computer Science 2023-02-10 Zaixiang Zheng , Yifan Deng , Dongyu Xue , Yi Zhou , Fei YE , Quanquan Gu

This paper is concerned with learning of mixture regression models for individuals that are measured repeatedly. The adjective "unsupervised" implies that the number of mixing components is unknown and has to be determined, ideally by data…

Methodology · Statistics 2018-01-09 Peirong Xu , Heng Peng , Tao Huang

For the majority of the learning-based segmentation methods, a large quantity of high-quality training data is required. In this paper, we present a novel learning-based segmentation model that could be trained semi- or un- supervised.…

Computer Vision and Pattern Recognition · Computer Science 2021-05-13 Junyu Chen , Eric C. Frey

Sentence compression reduces the length of text by removing non-essential content while preserving important facts and grammaticality. Unsupervised objective driven methods for sentence compression can be used to create customized models…

Computation and Language · Computer Science 2022-05-18 Demian Gholipour Ghalandari , Chris Hokamp , Georgiana Ifrim

Language models provide a key framework for studying linguistic theories based on prediction, but phonological analysis using large language models (LLMs) is difficult; there are few phonological benchmarks beyond English and the standard…

Computation and Language · Computer Science 2025-06-13 Zébulon Goriely , Paula Buttery
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