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Stop words, which are considered non-predictive, are often eliminated in natural language processing tasks. However, the definition of uninformative vocabulary is vague, so most algorithms use general knowledge-based stop lists to remove…

Software Engineering · Computer Science 2023-06-13 Yaohou Fan , Chetan Arora , Christoph Treude

Despite recent success in machine reading comprehension (MRC), learning high-quality MRC models still requires large-scale labeled training data, even using strong pre-trained language models (PLMs). The pre-training tasks for PLMs are not…

Computation and Language · Computer Science 2021-07-20 Ning Bian , Xianpei Han , Bo Chen , Hongyu Lin , Ben He , Le Sun

Introducing explicit constraints on the structural predictions has been an effective way to improve the performance of semantic segmentation models. Existing methods are mainly based on insufficient hand-crafted rules that only partially…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Boxi Wu , Shuai Zhao , Wenqing Chu , Zheng Yang , Deng Cai

Tissue segmentation is the mainstay of pathological examination, whereas the manual delineation is unduly burdensome. To assist this time-consuming and subjective manual step, researchers have devised methods to automatically segment…

Image and Video Processing · Electrical Eng. & Systems 2022-08-08 Yang Nan , Peng Tang , Guyue Zhang , Caihong Zeng , Zhihong Liu , Zhifan Gao , Heye Zhang , Guang Yang

A complete time-parameterized statistical model quantifying the divergent evolution of protein structures in terms of the patterns of conservation of their secondary structures is inferred from a large collection of protein 3D structure…

Quantitative Methods · Quantitative Biology 2023-08-15 Sandun Rajapaksa , Lloyd Allison , Peter J. Stuckey , Maria Garcia de la Banda , Arun S. Konagurthu

How does the input segmentation of pretrained language models (PLMs) affect their interpretations of complex words? We present the first study investigating this question, taking BERT as the example PLM and focusing on its semantic…

Computation and Language · Computer Science 2021-06-03 Valentin Hofmann , Janet B. Pierrehumbert , Hinrich Schütze

In this work, we have investigated a number of unsupervised learning methods for material segmentation in projection x-ray imaging with a spectral detector. A phantom containing two hard materials (glass, steel) and three soft materials…

Breaking down a document or a conversation into multiple contiguous segments based on its semantic structure is an important and challenging problem in NLP, which can assist many downstream tasks. However, current works on topic…

Computation and Language · Computer Science 2022-11-29 Reshmi Ghosh , Harjeet Singh Kajal , Sharanya Kamath , Dhuri Shrivastava , Samyadeep Basu , Soundararajan Srinivasan

Representation learning for proteins has primarily focused on the global understanding of protein sequences regardless of their length. However, shorter proteins (known as peptides) take on distinct structures and functions compared to…

Quantitative Methods · Quantitative Biology 2022-11-15 Gil Sadeh , Zichen Wang , Jasleen Grewal , Huzefa Rangwala , Layne Price

Recently developed deep learning techniques have significantly improved the accuracy of various speech and image recognition systems. In this paper we adapt some of these techniques for protein secondary structure prediction. We first train…

Machine Learning · Computer Science 2016-11-07 Akosua Busia , Jasmine Collins , Navdeep Jaitly

We consider the problem of training speech recognition systems without using any labeled data, under the assumption that the learner can only access to the input utterances and a phoneme language model estimated from a non-overlapping…

Audio and Speech Processing · Electrical Eng. & Systems 2018-12-27 Chih-Kuan Yeh , Jianshu Chen , Chengzhu Yu , Dong Yu

This dissertation presents several new methods of supervised and unsupervised learning of word sense disambiguation models. The supervised methods focus on performing model searches through a space of probabilistic models, and the…

Computation and Language · Computer Science 2009-09-29 Ted Pedersen

Cross-lingual word embeddings aim to bridge the gap between high-resource and low-resource languages by allowing to learn multilingual word representations even without using any direct bilingual signal. The lion's share of the methods are…

Computation and Language · Computer Science 2020-09-03 Magdalena Biesialska , Marta R. Costa-jussà

We consider the protein sequence engineering problem, which aims to find protein sequences with high fitness levels, starting from a given wild-type sequence. Directed evolution has been a dominating paradigm in this field which has an…

Machine Learning · Computer Science 2025-01-20 Yinkai Wang , Jiaxing He , Yuanqi Du , Xiaohui Chen , Jianan Canal Li , Li-Ping Liu , Xiaolin Xu , Soha Hassoun

Tandem duplication is the process of inserting a copy of a segment of DNA adjacent to the original position. Motivated by applications that store data in living organisms, Jain et al. (2017) proposed the study of codes that correct tandem…

Information Theory · Computer Science 2018-01-09 Yeow Meng Chee , Johan Chrisnata , Han Mao Kiah , Tuan Thanh Nguyen

Current protein language models (PLMs) learn protein representations mainly based on their sequences, thereby well capturing co-evolutionary information, but they are unable to explicitly acquire protein functions, which is the end goal of…

Biomolecules · Quantitative Biology 2023-07-06 Minghao Xu , Xinyu Yuan , Santiago Miret , Jian Tang

Purpose: This study aimed to enhance protein sequence classification using natural language processing (NLP) techniques while addressing the impact of sequence similarity on model performance. We compared various machine learning and deep…

Quantitative Methods · Quantitative Biology 2025-05-26 Huma Perveen , Julie Weeds

Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often struggle to produce proteins with precisely specified…

Biomolecules · Quantitative Biology 2025-09-15 Long-Kai Huang , Rongyi Zhu , Bing He , Jianhua Yao

This paper is aimed at reporting on the development and application of a computer model for discourse analysis through segmentation. Segmentation refers to the principled division of texts into contiguous constituents. Other studies have…

Computation and Language · Computer Science 2007-05-23 Tony Berber Sardinha

Keyphrase extraction aims at automatically extracting a list of "important" phrases representing the key concepts in a document. Prior approaches for unsupervised keyphrase extraction resorted to heuristic notions of phrase importance via…

Computation and Language · Computer Science 2023-02-20 Rishabh Joshi , Vidhisha Balachandran , Emily Saldanha , Maria Glenski , Svitlana Volkova , Yulia Tsvetkov
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