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We present an extension of sparse PCA, or sparse dictionary learning, where the sparsity patterns of all dictionary elements are structured and constrained to belong to a prespecified set of shapes. This \emph{structured sparse PCA} is…

Machine Learning · Statistics 2009-09-09 Rodolphe Jenatton , Guillaume Obozinski , Francis Bach

A statistical model for segmentation and word discovery in child directed speech is presented. An incremental unsupervised learning algorithm to infer word boundaries based on this model is described and results of empirical tests showing…

Computation and Language · Computer Science 2007-05-23 Anand Venkataraman

One of the basic tasks of computational language documentation (CLD) is to identify word boundaries in an unsegmented phonemic stream. While several unsupervised monolingual word segmentation algorithms exist in the literature, they are…

Computation and Language · Computer Science 2019-10-21 Pierre Godard , Laurent Besacier , Francois Yvon

Although word-level prosody modeling in neural text-to-speech (TTS) has been investigated in recent research for diverse speech synthesis, it is still challenging to control speech synthesis manually without a specific reference. This is…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-17 Yiwei Guo , Chenpeng Du , Kai Yu

Prepositions are very common and very ambiguous, and understanding their sense is critical for understanding the meaning of the sentence. Supervised corpora for the preposition-sense disambiguation task are small, suggesting a…

Computation and Language · Computer Science 2016-11-29 Hila Gonen , Yoav Goldberg

Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hedda Cohen Indelman , Elay Dahan , Angeles M. Perez-Agosto , Carmit Shiran , Doron Shaked , Nati Daniel

Most recent neural semi-supervised learning algorithms rely on adding small perturbation to either the input vectors or their representations. These methods have been successful on computer vision tasks as the images form a continuous…

Machine Learning · Computer Science 2019-11-27 Alexander Hanbo Li , Abhinav Sethy

Understanding the relationships between protein sequence, structure and function is a long-standing biological challenge with manifold implications from drug design to our understanding of evolution. Recently, protein language models have…

Quantitative Methods · Quantitative Biology 2024-01-29 Dexiong Chen , Philip Hartout , Paolo Pellizzoni , Carlos Oliver , Karsten Borgwardt

Modern Protein Language Models (PLMs) apply transformer-based model architectures from natural language processing to biological sequences, predicting a variety of protein functions and properties. However, protein language has key…

Machine Learning · Computer Science 2026-02-25 Anna Hart , Chi Han , Jeonghwan Kim , Huimin Zhao , Heng Ji

We present analysis of a novel tool for protein secondary structure prediction using the recently-investigated Neural Machine Translation framework. The tool provides a fast and accurate folding prediction based on primary structure with…

Quantitative Methods · Quantitative Biology 2021-05-11 Evan Weissburg , Ian Bulovic

Current Large Language Models (LLMs) for understanding proteins primarily treats amino acid sequences as a text modality. Meanwhile, Protein Language Models (PLMs), such as ESM-2, have learned massive sequential evolutionary knowledge from…

Machine Learning · Computer Science 2024-12-17 Nuowei Liu , Changzhi Sun , Tao Ji , Junfeng Tian , Jianxin Tang , Yuanbin Wu , Man Lan

Significant work has been done on learning regular expressions from a set of data values. Depending on the domain, this approach can be very successful. However, significant time is required to learn these expressions and the resulting…

Databases · Computer Science 2024-03-18 Michael J. Mior

Multi-criteria Chinese word segmentation is a promising but challenging task, which exploits several different segmentation criteria and mines their common underlying knowledge. In this paper, we propose a flexible multi-criteria learning…

Computation and Language · Computer Science 2018-12-20 Jingjing Gong , Xinchi Chen , Tao Gui , Xipeng Qiu

Complex questions that require inferencing and synthesizing information from multiple documents can be seen as a kind of topic-oriented, informative multi-document summarization where the goal is to produce a single text as a compressed…

Computation and Language · Computer Science 2014-01-16 Yllias Chali , Shafiq Rayhan Joty , Sadid A. Hasan

Recent work on segmentation-free word embedding(sembei) developed a new pipeline of word embedding for unsegmentated language while avoiding segmentation as a preprocessing step. However, too many noisy n-grams existing in the embedding…

Computation and Language · Computer Science 2020-07-08 Yifan Zhang , Maohua Wang , Yongjian Huang , Qianrong Gu

We introduce DisProtEdit, a controllable protein editing framework that leverages dual-channel natural language supervision to learn disentangled representations of structural and functional properties. Unlike prior approaches that rely on…

Quantitative Methods · Quantitative Biology 2025-06-19 Max Ku , Sun Sun , Hongyu Guo , Wenhu Chen

Subwords have become the standard units of text in NLP, enabling efficient open-vocabulary models. With algorithms like byte-pair encoding (BPE), subword segmentation is viewed as a preprocessing step applied to the corpus before training.…

Computation and Language · Computer Science 2022-10-14 Francois Meyer , Jan Buys

Amino acid sequence portrays most intrinsic form of a protein and expresses primary structure of protein. The order of amino acids in a sequence enables a protein to acquire a particular stable conformation that is responsible for the…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , David Fernandez-Baca , Akshay Deepak , Sudhakar Tripathi

Word feature vectors have been proven to improve many NLP tasks. With recent advances in unsupervised learning of these feature vectors, it became possible to train it with much more data, which also resulted in better quality of learned…

Computation and Language · Computer Science 2022-11-29 Marius Sajgalik , Michal Barla , Maria Bielikova

For sequence transduction tasks like speech recognition, a strong structured prior model encodes rich information about the target space, implicitly ruling out invalid sequences by assigning them low probability. In this work, we propose…

Computation and Language · Computer Science 2020-02-25 Wei-Ning Hsu , Ann Lee , Gabriel Synnaeve , Awni Hannun