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Protein-protein interaction (PPI) networks, providing a comprehensive landscape of protein interacting patterns, enable us to explore biological processes and cellular components at multiple resolutions. For a biological process, a number…

Molecular Networks · Quantitative Biology 2016-04-13 Xiuli Ma , Guangyu Zhou , Jingjing Wang , Jian Peng , Jiawei Han

In recent years, there has been remarkable progress in machine learning for protein-protein interactions. However, prior work has predominantly focused on improving learning algorithms, with less attention paid to evaluation strategies and…

Machine Learning · Computer Science 2024-04-17 Anton Bushuiev , Roman Bushuiev , Jiri Sedlar , Tomas Pluskal , Jiri Damborsky , Stanislav Mazurenko , Josef Sivic

Proteins employ the information stored in the genetic code and translated into their sequences to carry out well-defined functions in the cellular environment. The possibility to encode for such functions is controlled by the balance…

Biomolecules · Quantitative Biology 2018-05-24 A. Possenti , M. Vendruscolo , C. Camilloni , G. Tiana

Problems of search and recognition appear over different scales in biological systems. In this review we focus on the challenges posed by interactions between proteins, in particular transcription factors, and DNA and possible mechanisms…

Biomolecules · Quantitative Biology 2015-03-19 M. Sheinman , O. Bénichou , Y. Kafri , R. Voituriez

The knowledge regarding the function of proteins is necessary as it gives a clear picture of biological processes. Nevertheless, there are many protein sequences found and added to the databases but lacks functional annotation. The…

Quantitative Methods · Quantitative Biology 2018-09-13 Anu Vazhayil , Vinayakumar R , Soman KP

Feature selection plays an important role in the data mining process. It is needed to deal with the excessive number of features, which can become a computational burden on the learning algorithms. It is also necessary, even when…

Machine Learning · Computer Science 2015-10-13 Tarek Amr Abdallah , Beatriz de La Iglesia

The main objective of higher education institutions is to provide quality education to its students. One way to achieve highest level of quality in higher education system is by discovering knowledge for prediction regarding enrolment of…

Information Retrieval · Computer Science 2012-01-18 Brijesh Kumar Baradwaj , Saurabh Pal

High throughput sequencing techniques have highly impactedon modern biology, widening the gap between sequenced andannotated data. Automatic annotation tools are thereforeof the foremost importance to guide biologists' experiments. However,…

Machine Learning · Statistics 2016-10-02 Luca Masera

The amount of text that is generated every day is increasing dramatically. This tremendous volume of mostly unstructured text cannot be simply processed and perceived by computers. Therefore, efficient and effective techniques and…

Computation and Language · Computer Science 2017-07-31 Mehdi Allahyari , Seyedamin Pouriyeh , Mehdi Assefi , Saied Safaei , Elizabeth D. Trippe , Juan B. Gutierrez , Krys Kochut

In an effort to overcome the data deluge in computational biology and bioinformatics and to facilitate bioinformatics research in the era of big data, we identify some of the most influential algorithms that have been widely used in the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-03 Faraz Faghri , Sayed Hadi Hashemi , Mohammad Babaeizadeh , Mike A. Nalls , Saurabh Sinha , Roy H. Campbell

IT industries in current scenario have to struggle effectively in terms of cost, quality, service or innovation for their subsistence in the global market. Due to the swift transformation of technology, software industries owe to manage a…

Software Engineering · Computer Science 2014-02-12 Sangita Gupta , Suma V

Machine learning models are routinely integrated into process mining pipelines to carry out tasks like data transformation, noise reduction, anomaly detection, classification, and prediction. Often, the design of such models is based on…

Machine Learning · Computer Science 2024-02-21 Paolo Ceravolo , Sylvio Barbon Junior , Ernesto Damiani , Wil van der Aalst

Despite the success of CNN models on a variety of Image classification and segmentation tasks, their extensive computational and storage demands pose considerable challenges for real-world deployment on resource-constrained devices.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Ahmed Luqman , Khuzemah Qazi , Murray Patterson , Malik Jahan Khan , Imdadullah Khan

Fuzzy modeling has many advantages over the non-fuzzy methods, such as robustness against uncertainties and less sensitivity to the varying dynamics of nonlinear systems. Data-driven fuzzy modeling needs to extract fuzzy rules from the…

Systems and Control · Computer Science 2018-06-08 Erick de la Rosa , Wen Yu

We present a new approach to classification that combines data and knowledge. In this approach, data mining is used to derive association rules (possibly with negations) from data. Those rules are leveraged to increase the predictive…

Artificial Intelligence · Computer Science 2025-10-22 Gilles Audemard , Sylvie Coste-Marquis , Pierre Marquis , Mehdi Sabiri , Nicolas Szczepanski

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

Feature selection techniques are essential for high-dimensional data analysis. In the last two decades, their popularity has been fuelled by the increasing availability of high-throughput biomolecular data where high-dimensionality is a…

Quantitative Methods · Quantitative Biology 2024-01-18 Pengyi Yang , Hao Huang , Chunlei Liu

One essential task in information extraction from the medical corpus is drug name recognition. Compared with text sources come from other domains, the medical text is special and has unique characteristics. In addition, the medical text…

Computation and Language · Computer Science 2016-10-07 Sadikin Mujiono , Mohamad Ivan Fanany , Chan Basaruddin

A hypercomplex representation of DNA is proposed to facilitate comparison of DNA sequences with fuzzy composition. Using hypercomplex number representation, conventional sequence analysis method, such as, dot matrix analysis, dynamic…

Quantitative Methods · Quantitative Biology 2023-08-03 Jian-Jun Shu , Yajing Li

Data collection and labeling are critical bottlenecks in the deployment of machine learning applications. With the increasing complexity and diversity of applications, the need for efficient and scalable data collection and labeling…

Databases · Computer Science 2024-07-19 Qianyu Huang , Tongfang Zhao
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