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Data mining is the task of discovering interesting, unexpected or valuable structures in large datasets and transforming them into an understandable structure for further use . Different approaches in the domain of data mining have been…

Databases · Computer Science 2020-09-21 Julie Bu Daher , Armelle Brun , Anne Boyer

Data mining algorithms are now able to efficiently deal with huge amount of data. Various kinds of patterns may be discovered and may have some great impact on the general development of knowledge. In many domains, end users may want to…

Artificial Intelligence · Computer Science 2009-02-09 Baptiste Jeudy , Christine Largeron , François Jacquenet

In many areas of science multiple sets of data are collected pertaining to the same system. Examples are food products which are characterized by different sets of variables, bio-processes which are on-line sampled with different…

In DNA computing, it is impossible to decide whether a specific hybridization among complex DNA molecules is effective or not within acceptable time. In order to address this common problem, we introduce a new method based on the machine…

Quantitative Methods · Quantitative Biology 2018-07-03 Weijun Zhu

Learning meaningful protein representation is important for a variety of biological downstream tasks such as structure-based drug design. Having witnessed the success of protein sequence pretraining, pretraining for structural data which is…

Machine Learning · Computer Science 2023-02-23 Yufei Huang , Lirong Wu , Haitao Lin , Jiangbin Zheng , Ge Wang , Stan Z. Li

Deep neural networks, particularly Transformers, have been widely adopted for predicting the functional properties of proteins. In this work, we focus on exploring whether Protein Transformers can capture biological intelligence among…

Machine Learning · Computer Science 2025-06-10 Fudong Lin , Wanrou Du , Jinchan Liu , Tarikul Milon , Shelby Meche , Wu Xu , Xiaoqi Qin , Xu Yuan

Rapid progress in deep learning has spurred its application to bioinformatics problems including protein structure prediction and design. In classic machine learning problems like computer vision, progress has been driven by standardized…

Biomolecules · Quantitative Biology 2019-02-04 Mohammed AlQuraishi

In systems biology, it is common to measure biochemical entities at different levels of the same biological system. One of the central problems for the data fusion of such data sets is the heterogeneity of the data. This thesis discusses…

Genomics · Quantitative Biology 2019-08-27 Yipeng Song

In today's data driven world, storing, processing, and gleaning insights from large-scale data are major challenges. Data compression is often required in order to store large amounts of high-dimensional data, and thus, efficient inference…

Machine Learning · Statistics 2018-09-11 Denali Molitor , Deanna Needell

There is increased interest in the identification and analysis of gene fusions and chimeric RNA transcripts. While most recent efforts focused on the analysis of genomic and transcriptomic data, identi-fication of novel peptides…

Quantitative Methods · Quantitative Biology 2014-08-22 Kang Ning , Alexey I. Nesvizhskii

Fuzzy systems have good modeling capabilities in several data science scenarios, and can provide human-explainable intelligence models with explainability and interpretability. In contrast to transaction data, which have been extensively…

Databases · Computer Science 2021-03-31 Wensheng Gan , Zilin Du , Weiping Ding , Chunkai Zhang , Han-Chieh Chao

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

We introduce a pioneering methodology for boosting large language models in the domain of protein representation learning. Our primary contribution lies in the refinement process for correlating the over-reliance on co-evolution knowledge,…

Artificial Intelligence · Computer Science 2024-12-05 Yaoyao Xu , Xinjian Zhao , Xiaozhuang Song , Benyou Wang , Tianshu Yu

The last twenty years have witnessed molecular data emerge as a primary research instrument in most branches of mycology. Fungal systematics, taxonomy, and ecology have all seen tremendous progress and have undergone rapid, far-reaching…

Social network has gained remarkable attention in the last decade. Accessing social network sites such as Twitter, Facebook LinkedIn and Google+ through the internet and the web 2.0 technologies has become more affordable. People are…

Social and Information Networks · Computer Science 2023-06-22 Mariam Adedoyin-Olowe , Mohamed Medhat Gaber , Frederic Stahl

Data mining is an increasingly important technology for extracting useful knowledge hidden in large collections of data. There are, however, negative social perceptions about data mining, among which potential privacy violation and…

Databases · Computer Science 2013-07-01 Sara Hajian

The use of patterns in predictive models is a topic that has received a lot of attention in recent years. Pattern mining can help to obtain models for structured domains, such as graphs and sequences, and has been proposed as a means to…

Artificial Intelligence · Computer Science 2011-11-29 Björn Bringmann , Siegfried Nijssen , Albrecht Zimmermann

Accurate localization of proteins from fluorescence microscopy images is challenging due to the inter-class similarities and intra-class disparities introducing grave concerns in addressing multi-class classification problems. Conventional…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Muhammad Tahir , Saeed Anwar , Ajmal Mian , Abdul Wahab Muzaffar

Large scale initiatives such as the Human Genome Project, Structural Genomics, and individual research teams have provided large deposits of genomic and proteomic data. The transfer of data to knowledge has become one of the existing…

Databases · Computer Science 2019-11-21 Casey A Cole , Christopher Ott , Diego Valdes , Homayoun Valafar

Data classification techniques partition the data or feature space into smaller sub-spaces, each corresponding to a specific class. To classify into subspaces, physical features e.g., distance and distributions are utilized. This approach…

Machine Learning · Computer Science 2025-03-11 Josimar Chire , Khalid Mahmood , Zhao Liang
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