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A commonly accepted feature of an excitable medium is that a local excitation leads to a propagation of circular or spiral excitation wave-fronts. This is indeed the case in fully excitable medium. However, with a decrease of an…

Emerging Technologies · Computer Science 2019-04-16 Andrew Adamatzky

Living cells employ excitable reaction-diffusion waves for internal cellular functions, in which curvature-inducing proteins are often involved. However, the role of their mechanochemical coupling is not well understood. Here, we report the…

Soft Condensed Matter · Physics 2022-08-09 Naoki Tamemoto , Hiroshi Noguchi

It is known that curvature relation plays a key role in the propagation of two-dimensional waves in an excitable model. Such a relation is believed to obey the eikonal equation for typical excitable models (e.g., the FitzHugh-Nagumo (FHN)…

Dynamical Systems · Mathematics 2014-02-20 Wenjun Zhang , James Sneyd , Je-Chiang Tsai

Reaction-diffusion waves in multiple spatial dimensions advance at a rate that strongly depends on the curvature of the wave fronts. These waves have important applications in many physical, ecological, and biological systems. In this work,…

Pattern Formation and Solitons · Physics 2022-12-28 Pascal R. Buenzli , Matthew J. Simpson

The Fitzhugh-Nagumo equations have been used as a caricature of the Hodgkin-Huxley equations of neuron firing to better understand the essential dynamics of the interaction of the membrane potential and the restoring force and to capture,…

Neurons and Cognition · Quantitative Biology 2007-05-23 F. Berezovskaya , E. Camacho , S. Wirkus , G. Karev

Pattern dynamics on curved surfaces are found everywhere in nature. The geometry of surfaces have been shown to influence dynamics and play a functional role, yet a comprehensive understanding is still elusive. Here, we report for the first…

Pattern Formation and Solitons · Physics 2022-06-15 Ryosuke Nishide , Shuji Ishihara

Many multicellular communities propagate signals in a directed manner via excitable waves. Cell-to-cell heterogeneity is a ubiquitous feature of multicellular communities, but the effects of heterogeneity on wave propagation are still…

Biological Physics · Physics 2020-04-22 Xiaoling Zhai , Joseph W. Larkin , Gürol M. Süel , Andrew Mugler

We consider the problem of initiation of propagating wave in a one-dimensional excitable fiber. In the FitzHugh-Nagumo theory, the key role is played by ``critical nucleus'' and ``critical pulse'' solutions whose (center-)stable manifold is…

Pattern Formation and Solitons · Physics 2009-11-13 I. Idris , V. N. Biktashev

Motivated by recent experiments on intracellular calcium dynamics, we study the general issue of fluctuation-induced nucleation of waves in excitable media. We utilize a stochastic Fitzhugh-Nagumo model for this study, a spatially-extended…

Condensed Matter · Physics 2009-11-10 Herve Henry , Herbert Levine

Nucleation and growth is the dominant relaxation mechanism driving first order phase transitions. In two-dimensional at systems nucleation has been applied to a wide range of problems in physics, chemistry and biology. Here we study…

Soft Condensed Matter · Physics 2016-03-09 Leopoldo R. Gomez , Nicolas A. Garcia , Vincenzo Vitelli , Jose Lorenzana , Daniel A. Vega

We study the effects of nonlocal control of pulse propagation in excitable media. As a generic example for an excitable medium the FitzHugh-Nagumo model with diffusion in the activator variable is considered. Nonlocal coupling in form of an…

Pattern Formation and Solitons · Physics 2015-06-19 Clemens A. Bachmair , Eckehard Schöll

Recent experiments have revealed that the meniscus formed near a surface-piercing barrier can significantly alter the propagation and scattering of capillary-gravity surface waves, beyond what classic flat-surface models predict. In…

Fluid Dynamics · Physics 2025-04-17 Guoqin Liu , Zhengwu Wang , Likun Zhang

Understanding how external stimuli propagate in neural systems is an important challenge in the fields of neuroscience and nonlinear dynamics. Despite extensive studies over several decades, this problem remains poorly understood. In this…

Neurons and Cognition · Quantitative Biology 2025-03-13 L. Messee Goulefack , C. Masoller , R. Yamapi , C. Anteneodo

We study the propagation of surface waves across structured surfaces with random, localized inhomogeneities. A discrete analogue of Gurtin-Murdoch model is employed and surface elasticity, in contrast to bulk elasticity, is captured by…

Mathematical Physics · Physics 2024-07-09 Josselin Garnier , Basant Lal Sharma

We investigate diffusion-driven instabilities in a FitzHugh-Nagumo reaction-diffusion system with superdiffusive transport, modeled by fractional Laplacian operators with different diffusion orders for the activator and the inhibitor. A…

Pattern Formation and Solitons · Physics 2026-03-04 Rossella Rizzo , Gaetana Gambino , Vincenzo Sciacca , Marco Sammartino

Pattern dynamics on curved surfaces are ubiquitous. Although the effect of surface topography on pattern dynamics has gained much interest, there is a limited understanding of the roles of surface geometry and topology in pattern dynamics.…

Pattern Formation and Solitons · Physics 2024-03-27 Ryosuke Nishide , Shuji Ishihara

The mechanics of lower dimensional elastic structures depends strongly on the geometry of their stress-free state. Elastic deformations separate into in-plane stretching and lower energy out-of-plane bending deformations. For elastic…

Soft Condensed Matter · Physics 2021-01-20 Jonathan Kernes , Alex J. Levine

We consider the propagation of flexural waves across a nearly flat, thin membrane, whose stress-free state is curved. The stress-free configuration is specified by a quenched height field, whose Fourier components are drawn from a Gaussian…

Soft Condensed Matter · Physics 2021-05-19 Jonathan Kernes , Alex J. Levine

We investigate wave propagation in rotationally symmetric tubes with a periodic spatial modulation of cross section. Using an asymptotic perturbation analysis, the governing quasi two-dimensional reaction-diffusion equation can be reduced…

Pattern Formation and Solitons · Physics 2017-01-05 A. Ziepke , S. Martens , H. Engel

For scalar reaction-diffusion equations, a traveling wave is a front which transforms a higher energy state to a lower energy state. The same is true for a system of equations with a gradient structure. At the core of this phenomenon, the…

Analysis of PDEs · Mathematics 2018-07-06 Chao-Nien Chen , Y. S. Choi
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