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Monte Carlo (MC) simulations are used to study the dynamics of polymer translocation through a nanopore in the limit where the translocation rate is sufficiently slow that the polymer maintains a state of conformational quasi-equilibrium.…

Soft Condensed Matter · Physics 2015-06-12 James M. Polson , Anthony C. M. McCaffrey

We revisit the Fokker-Planck based theory of driven polymer translocation through a narrow nanopore. A bead-spring model of a uniformly charged polyelectrolyte chain translocating through a semi-implicit model of a nanopore embedded in a…

Soft Condensed Matter · Physics 2025-12-02 Bhavesh R. Sarode , Harshwardhan H. Katkar

One of the major theoretical methods in understanding polymer translocation through a nanopore is the Fokker-Planck formalism based on the assumption of quasi-equilibrium of polymer conformations. The criterion for applicability of the…

Soft Condensed Matter · Physics 2018-02-14 Harshwardhan H. Katkar , Murugappan Muthukumar

We suggest a theoretical description of the force-induced translocation dynamics of a polymer chain through a nanopore. Our consideration is based on the tensile (Pincus) blob picture of a pulled chain and the notion of propagating front of…

Soft Condensed Matter · Physics 2012-04-17 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

We suggest a governing equation which describes the process of polymer chain translocation through a narrow pore and reconciles the seemingly contradictory features of such dynamics: (i) a Gaussian probability distribution of the…

Soft Condensed Matter · Physics 2011-02-15 Johan L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

We present a Brownian dynamics model of driven polymer translocation, in which non-equilibrium memory effects arising from tension propagation (TP) along the cis side subchain are incorporated as a time-dependent friction. To solve the…

Soft Condensed Matter · Physics 2015-06-03 Timo Ikonen , Aniket Bhattacharya , Tapio Ala-Nissila , Wokyung Sung

We investigate polymer translocation through a nanopore under a pulling force using Langevin dynamics simulations. We concentrate on the influence of the chain length $N$ and the pulling force $F$ on the translocation time $\tau$. The…

Soft Condensed Matter · Physics 2007-06-27 Ilkka Huopaniemi , Kaifu luo , Tapio Ala-Nissila , See-Chen Ying

The impact of thermal fluctuations on the translocation dynamics of a polymer chain driven through a narrow pore has been investigated theoretically and by means of extensive Molecular-Dynamics (MD) simulation. The theoretical consideration…

Soft Condensed Matter · Physics 2015-06-12 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

We study translocation of semiflexible polymers driven by force $f_d$ inside a nanometer-scale pore using our three-dimensional Langevin dynamics model. We show that the translocation time $\tau$ increases with increasing bending rigidity…

Biological Physics · Physics 2018-06-27 Pauli M. Suhonen , Riku P. Linna

We study the driven translocation of a semi-flexible polymer through a nanopore by means of a modified version of the iso-flux tension propagation theory (IFTP), and extensive molecular dynamics (MD) simulations. We show that in contrast to…

Soft Condensed Matter · Physics 2016-12-28 Jalal Sarabadani , Timo Ikonen , Harri Mökkönen , Tapio Ala-Nissila , Spencer Carson , Meni Wanunu

We investigate the dynamics of polymer translocation through nanopores under external driving by 3D Langevin Dynamics simulations, focusing on the scaling of the average translocation time $\tau$ versus the length of the polymer, $\tau\sim…

Soft Condensed Matter · Physics 2010-01-04 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Ralf Metzler

We study the translocation dynamics of a polymer chain threaded through a nanopore by an external force. By means of diverse methods (scaling arguments, fractional calculus and Monte Carlo simulation) we show that the relevant dynamic…

Statistical Mechanics · Physics 2007-07-29 J. L. A. Dubbeldam , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

We investigate the dynamics of polymer translocation through a nanopore using two-dimensional Langevin dynamics simulations. In the absence of external driving force, we consider a polymer which is initially placed in the middle of the pore…

Soft Condensed Matter · Physics 2007-05-23 Ilkka Huopaniemi , Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying

We consider the dynamics of pore-driven polymer translocation through a nanopore to semi-infinite space when the chain is initially confined and equilibrated in a narrow channel. To this end, we use Langevin dynamics (LD) simulations and…

Soft Condensed Matter · Physics 2025-03-11 Soheila Emamyari , Jalal Sarabadani , Ralf Metzler , Tapio Ala-Nissila

Polymer translocation has long been a topic of interest in the field of biological physics given its relevance in both biological (protein and DNA/RNA translocation through nuclear and cell membranes) and technological processes (nanopore…

Soft Condensed Matter · Physics 2023-09-11 Alejandro Sainz-Agost , Fernando Falo , Alessandro Fiasconaro

We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory…

Soft Condensed Matter · Physics 2018-02-14 Jalal Sarabadani , Bappa Ghosh , Srabanti Chaudhury , Tapio Ala-Nissila

The translocation time of a polymer chain through an interaction energy gradient nanopore was studied by Monte Carlo simulations and the Fokker-Planck equation with double-absorbing boundary conditions. Both the simulation and calculation…

Soft Condensed Matter · Physics 2017-01-04 Meng-Bo Luo , Shuang Zhang , Fan Wu , Li-Zhen Sun

We develop a theory for polymer translocation driven by a time-dependent force through an oscillating nanopore. To this end, we extend the iso-flux tension propagation theory (IFTP) [Sarabadani \textit{et al., J. Chem. Phys.}, 2014,…

Statistical Mechanics · Physics 2015-09-02 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

We investigate the dynamics of polymer translocation through a nanopore under an externally applied field using the 2D fluctuating bond model with single-segment Monte Carlo moves. We concentrate on the influence of the field strength $E$,…

Soft Condensed Matter · Physics 2011-08-26 Kaifu Luo , Ilkka Huopaniemi , Tapio Ala-Nissila , See-Chen Ying

Using two dimensional Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a fluidic channel with diameter $R$ through a nanopore under a driving force $F$. Due to the crowding effect induced by the…

Soft Condensed Matter · Physics 2010-08-30 Kaifu Luo , Ralf Metzler
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