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Gaussian processes (GPs) are a widely used regression tool, but the cubic complexity of exact solvers limits their scalability. To address this challenge, we extend the GPRat library by incorporating a fully GPU-resident GP prediction…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-24 Henrik Möllmann , Dirk Pflüger , Alexander Strack

Linked-Reads technologies, such as 10x Genomics, combine both the high-quality and low cost of short-reads sequencing and a long-range information, through the use of barcodes able to tag reads which originate from a common long DNA…

Genomics · Quantitative Biology 2021-03-30 Pierre Morisse , Claire Lemaitre , Fabrice Legeai

Convolutional Neural Networks (CNNs) have shown to be powerful classification tools in tasks that range from check reading to medical diagnosis, reaching close to human perception, and in some cases surpassing it. However, the problems to…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-08 Jose Marques , Gabriel Falcao , Luís A. Alexandre

Massively parallel DNA sequencing technologies are revolutionizing genomics research. Billions of short reads generated at low costs can be assembled for reconstructing the whole genomes. Unfortunately, the large memory footprint of the…

Data Structures and Algorithms · Computer Science 2012-07-17 Yang Li , Pegah Kamousi , Fangqiu Han , Shengqi Yang , Xifeng Yan , Subhash Suri

Graph Neural Networks (GNNs) are powerful deep learning models to generate node embeddings on graphs. When applying deep GNNs on large graphs, it is still challenging to perform training in an efficient and scalable way. We propose a novel…

Machine Learning · Computer Science 2020-10-08 Hanqing Zeng , Hongkuan Zhou , Ajitesh Srivastava , Rajgopal Kannan , Viktor Prasanna

Breadth-first Search (BFS) is one of the most important graph processing subroutines, especially for computing the unweighted distance. Many applications may require running BFS from multiple sources. Sequentially, when running BFS on a…

Data Structures and Algorithms · Computer Science 2024-10-29 Letong Wang , Guy Blelloch , Yan Gu , Yihan Sun

Btrim is a fast and lightweight software to trim adapters and low quality regions in reads from ultra high-throughput next-generation sequencing machines. It also can reliably identify barcodes and assign the reads to the original samples.…

Genomics · Quantitative Biology 2024-05-28 Yong Kong

Large-scale genomic workflows used in precision medicine can process datasets spanning tens to hundreds of gigabytes per sample, leading to high memory spikes, intensive disk I/O, and task failures due to out-of-memory errors. Simple static…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-21 Daniel Mas Montserrat , Ray Verma , Míriam Barrabés , Francisco M. de la Vega , Carlos D. Bustamante , Alexander G. Ioannidis

Recent advancements in Diffusion Transformers (DiTs) have established them as the state-of-the-art method for video generation. However, their inherently sequential denoising process results in inevitable latency, limiting real-world…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hanshuai Cui , Zhiqing Tang , Zhifei Xu , Zhi Yao , Wenyi Zeng , Weijia Jia

We introduce Breadth-First Pipeline Parallelism, a novel training schedule which optimizes the combination of pipeline and data parallelism. Breadth-First Pipeline Parallelism lowers training time, cost and memory usage by combining a high…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-10 Joel Lamy-Poirier

Force-directed algorithms are widely used to generate aesthetically pleasing layouts of graphs or networks arisen in many scientific disciplines. To visualize large-scale graphs, several parallel algorithms have been discussed in the…

Social and Information Networks · Computer Science 2020-02-26 Md. Khaledur Rahman , Majedul Haque Sujon , Ariful Azad

Effective attention modules have played a crucial role in the success of Transformer-based large language models (LLMs), but the quadratic time and memory complexities of these attention modules also pose a challenge when processing long…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-07 Ao Sun , Weilin Zhao , Xu Han , Cheng Yang , Zhiyuan Liu , Chuan Shi , Maosong Sun

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

Single-cell sequencing technologies reveal cellular heterogeneity at high resolution, advancing our understanding of biological complexity. As datasets start to scale to tens of millions of cells, computational workflows face substantial…

Motivation: The availability of thousands of invidual genomes of one species should boost rapid progress in personalized medicine or understanding of the interaction between genotype and phenotype, to name a few applications. A key…

Computational Engineering, Finance, and Science · Computer Science 2017-03-03 Agnieszka Danek , Sebastian Deorowicz , Szymon Grabowski

In recent work, we have shown that NVIDIA's raytracing cores on RTX video cards can be exploited to realize hardware-accelerated lookups for GPU-resident database indexes. On a high level, the concept materializes all keys as triangles in a…

Databases · Computer Science 2025-06-06 Justus Henneberg , Felix Schuhknecht , Rosina Kharal , Trevor Brown

The push-relabel algorithm is an efficient algorithm that solves the maximum flow/ minimum cut problems of its affinity to parallelization. As the size of graphs grows exponentially, researchers have used Graphics Processing Units (GPUs) to…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-02 Chou-Ying Hsieh , Po-Chieh Lin , Sy-Yen Kuo

Modern machine learning models are typically trained using Stochastic Gradient Descent (SGD) on massively parallel computing resources such as GPUs. Increasing mini-batch size is a simple and direct way to utilize the parallel computing…

Machine Learning · Statistics 2019-03-05 Siyuan Ma , Mikhail Belkin

Learning continuous representations of nodes is attracting growing interest in both academia and industry recently, due to their simplicity and effectiveness in a variety of applications. Most of existing node embedding algorithms and…

Machine Learning · Computer Science 2019-03-05 Zhaocheng Zhu , Shizhen Xu , Meng Qu , Jian Tang

The Continuous Wavelet Transform (CWT) is an effective tool for feature extraction in acoustic recognition using Convolutional Neural Networks (CNNs), particularly when applied to non-stationary audio. However, its high computational cost…

Audio and Speech Processing · Electrical Eng. & Systems 2025-12-01 Dang Thoai Phan , Tuan Anh Huynh , Van Tuan Pham , Cao Minh Tran , Van Thuan Mai , Ngoc Quy Tran