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The positional Burrows-Wheeler Transform (PBWT) is commonly used to store haplotype panels compactly in such a way that, given a query haplotype, we can quickly find the set maximal exact matches (SMEMs) between the query and the haplotypes…

Data Structures and Algorithms · Computer Science 2026-05-26 Travis Gagie

Binary code analysis is widely used to assess a program's correctness, performance, and provenance. Binary analysis applications often construct control flow graphs, analyze data flow, and use debugging information to understand how machine…

In this paper we propose a flexible and lightweight technique for merging compressed indices based on variants of Burrows-Wheeler transform (BWT), thus addressing the need for algorithms that compute compressed indices over large…

Data Structures and Algorithms · Computer Science 2019-03-06 Lavinia Egidi , Giovanni Manzini

Indexing highly repetitive strings (i.e., strings with many repetitions) for fast queries has become a central research topic in string processing, because it has a wide variety of applications in bioinformatics and natural language…

Data Structures and Algorithms · Computer Science 2021-04-19 Takaaki Nishimoto , Yasuo Tabei

Benefitting from large-scale training datasets and the complex training network, Convolutional Neural Networks (CNNs) are widely applied in various fields with high accuracy. However, the training process of CNNs is very time-consuming,…

Machine Learning · Computer Science 2019-11-26 Jianguo Chen , Kenli Li , Kashif Bilal , Xu Zhou , Keqin Li , Philip S. Yu

Probabilistic breadth-first traversals (BPTs) are used in many network science and graph machine learning applications. In this paper, we are motivated by the application of BPTs in stochastic diffusion-based graph problems such as…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-21 Reece Neff , Mostafa Eghbali Zarch , Marco Minutoli , Mahantesh Halappanavar , Antonino Tumeo , Ananth Kalyanaraman , Michela Becchi

At the last step of short read mapping, the candidate locations of the reads on the reference genome are verified to compute their differences from the corresponding reference segments using sequence alignment algorithms. Calculating the…

Genomics · Quantitative Biology 2024-07-04 Zülal Bingöl , Mohammed Alser , Onur Mutlu , Ozcan Ozturk , Can Alkan

Convolutional neural networks have gained a remarkable success in computer vision. However, most usable network architectures are hand-crafted and usually require expertise and elaborate design. In this paper, we provide a block-wise…

Computer Vision and Pattern Recognition · Computer Science 2018-08-17 Zhao Zhong , Zichen Yang , Boyang Deng , Junjie Yan , Wei Wu , Jing Shao , Cheng-Lin Liu

Pairwise sequence alignment is one of the most computationally intensive kernels in genomic data analysis, accounting for more than 90% of the runtime for key bioinformatics applications. This method is particularly expensive for…

In recent years graphical processing units (GPUs) have become a powerful tool in scientific computing. Their potential to speed up highly parallel applications brings the power of high performance computing to a wider range of users.…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-26 Uldis Locans , Andreas Adelmann , Andreas Suter , Jannis Fischer , Werner Lustermann , Gunther Dissertori , Qiulin Wang

With the advance in genome sequencing technology, the lengths of deoxyribonucleic acid (DNA) sequencing results are rapidly increasing at lower prices than ever. However, the longer lengths come at the cost of a heavy computational burden…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-12 Seongyeon Park , Junguk Hong , Jaeyong Song , Hajin Kim , Youngsok Kim , Jinho Lee

The Burrows-Wheeler Transform (BWT) is a word transformation introduced in 1994 for Data Compression. It has become a fundamental tool for designing self-indexing data structures, with important applications in several area in science and…

Data Structures and Algorithms · Computer Science 2019-07-05 Raffaele Giancarlo , Giovanni Manzini , Antonio Restivo , Giovanna Rosone , Marinella Sciortino

Betweenness Centrality (BC) is steadily growing in popularity as a metrics of the influence of a vertex in a graph. The BC score of a vertex is proportional to the number of all-pairs-shortest-paths passing through it. However, complete and…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-22 Flavio Vella , Giancarlo Carbone , Massimo Bernaschi

Capacitive coupling wireless power transfer (CCWPT) is one of the pervasive methods to transfer power in the reactive near-field zone. In this paper, a flexible design methodology based on Binary Particle Swarm Optimization (BPSO) algorithm…

Systems and Control · Electrical Eng. & Systems 2024-08-22 Rasool Keshavarz , Ehsan Majidi , Ali Raza , Negin Shariati

The Transformer architecture has shown significant success in many language processing and visual tasks. However, the method faces challenges in efficiently scaling to long sequences because the self-attention computation is quadratic with…

Machine Learning · Computer Science 2025-05-05 Edison Mucllari , Zachary Daniels , David Zhang , Qiang Ye

Graph Convolutional Networks (GCNs) are recently getting much attention in bioinformatics and chemoinformatics as a state-of-the-art machine learning approach with high accuracy. GCNs process convolutional operations along with graph…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-03-28 Yusuke Nagasaka , Akira Nukada , Ryosuke Kojima , Satoshi Matsuoka

Conventional neural accelerators rely on isolated self-sufficient functional units that perform an atomic operation while communicating the results through an operand delivery-aggregation logic. Each single unit processes all the bits of…

Machine Learning · Computer Science 2020-04-14 Soroush Ghodrati , Hardik Sharma , Cliff Young , Nam Sung Kim , Hadi Esmaeilzadeh

Reading a qubit is a fundamental operation in quantum computing. It translates quantum information into classical information enabling subsequent classification to assign the qubit states `0' or `1'. Unfortunately, qubit readout is one of…

Structural clustering is one of the most popular graph clustering methods, which has achieved great performance improvement by utilizing GPUs. Even though, the state-of-the-art GPU-based structural clustering algorithm, GPUSCAN, still…

Databases · Computer Science 2023-12-01 Long Yuan , Zeyu Zhou , Xuemin Lin , Zi Chen , Xiang Zhao , Fan Zhang

The rapid advancement of GPU technology has unlocked powerful parallel processing capabilities, creating new opportunities to enhance classic search algorithms. This hardware has been exploited in best-first search algorithms with neural…

Artificial Intelligence · Computer Science 2025-11-18 Ehsan Futuhi , Nathan R. Sturtevant
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