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For a wide range of modern soft functional materials the selective transport of sub-nanometer-sized molecules (`penetrants') through a stimuli-responsive polymeric membrane is key to the desired function. In this study, we investigate the…

Soft Condensed Matter · Physics 2018-08-28 Matej Kanduc , Won Kyu Kim , Rafael Roa , Joachim Dzubiella

The hydrodynamic effects of macromolecular crowding inside cells is often studied in vitro by using polymers as crowding reagents. Confinement of polymers inside cell-sized droplets has been shown to affect the diffusion of small molecules.…

Soft Condensed Matter · Physics 2023-04-28 Yaam Deckel , Lauren A. Lowe , Siddharth Rawat , Matthew Turner , James Luong , Anna Wang

Experiments on supported lipid bilayers featuring liquid ordered/disordered domains have shown that the spatial arrangement of the lipid domains and their chemical composition are strongly affected by the curvature of the substrate.…

Soft Condensed Matter · Physics 2021-02-17 Melissa Rinaldin , Piermarco Fonda , Luca Giomi , Daniela J. Kraft

Several methods now exist to solvate lipid bilayer discoids at the scale of tens of nanometres. Due to their size, such nanodiscoids have a comparatively large boundary-to-area ratio, making them unusually well-suited to probing the effects…

Soft Condensed Matter · Physics 2019-04-02 R. G. Morris , T. R. Dafforn , M. S. Turner

Single gold nanoparticles can act as nanoantennas for enhancing the fluorescence of emitters in their near-fields. Here we present experimental and theoretical studies of scanning antenna-based fluorescence microscopy as a function of the…

Confining light in extreme subwavelength scales is a tantalizing task. In this work, we report a study of individual plasmonic film-coupled nanostar resonators where plasmonic optical modes are trapped in ultrasmall volumes. Individual gold…

Gold nanoparticles (GNPs) constitute a breakthrough in modern chemistry. The recent success in the synthesis and total structure determination of the precise-composition GNPs provides exciting opportunities for fundamental studies and…

Materials Science · Physics 2015-02-05 Vitaly Chaban

Although promising for biomedicine, the clinical translation of inorganic nanoparticles (NPs) is limited by low biocompatibility and stability in biological fluids. A common strategy to circumvent this drawback consists in disguising the…

Soft-solid molecular crystals consist of crystalline grains and fluid grain boundaries (GB) that enhance grain binding and transport of Li+ ions between the grains. The total ionic conductivity consists of ion migration in both the grains…

Enzymes have been shown to diffuse faster in the presence of their reactants. Recently, we revealed new insights into this process of enhanced diffusion using single-particle tracking (SPT) with total internal reflection fluorescence (TIRF)…

Biological Physics · Physics 2021-01-01 Mengqi Xu , W. Benjamin Rogers , Wylie W. Ahmed , Jennifer L. Ross

In this work we describe a set of Coarse-grained (CG) tools that allow to simulate the uptake of the nanoparticles (NPs) coated with proteins by a lipid bilayer. We describe a CG model to calculate the adsorption energies and the most…

Soft Condensed Matter · Physics 2015-11-23 Hender Lopez , Erik Brandt , Alexander Mirzoev , Dmitry Zhurkin , Alexander Lyubartsev , Vladimir Lobaskin

Recent progresses in single particle tracking have shown evidences of non-Gaussian distribution of displacements in living cells, both near the cellular membrane and inside the cytoskeleton. A similar behavior has also been observed in…

Biological Physics · Physics 2019-05-30 Yann Lanoiselée , Denis S. Grebenkov

We measure diffusion of organic molecules located a few nanometers from the diamond surface. To study molecular diffusion, we perform local detection of nuclear magnetic resonance, based on single shallow Nitrogen-Vacancy (NV) centers in…

Mesoscale and Nanoscale Physics · Physics 2021-05-18 Farida Shagieva , Andrea Zappe , Daniel Cohen , Andrej Denisenko , Alex Retzker , Jörg Wrachtrup

Computational modeling and accurate simulations of localized surface plasmon resonance (LSPR) absorption properties are reported for gold nanobipyramids (GNBs), a class of metal nanoparticle that features highly tunable, geometrydependent…

This study consolidates Multi-Level Starlet Segmentation (MLSS) and Multi-Level Starlet Optimal Segmentation (MLSOS), techniques for photomicrograph segmentation that use starlet wavelet detail levels to separate areas of interest in an…

Computer Vision and Pattern Recognition · Computer Science 2017-06-14 Alexandre Fioravante de Siqueira , Flávio Camargo Cabrera , Aylton Pagamisse , Aldo Eloizo Job

Photothermal therapies are based on the optical excitation of plasmonic nanoparticles in the biological environment. The effects of the irradiation on the biological medium depend critically on the heat transfer process at the nanoparticle…

Computational Physics · Physics 2017-11-21 Andrea Torchi , Federica Simonelli , Riccardo Ferrando , Giulia Rossi

We report a high energy-resolution neutron backscattering study to investigate slow motions on nanosecond time scales in highly oriented solid supported phospholipid bilayers of the model system DMPC -d54 (deuterated…

Soft Condensed Matter · Physics 2007-05-23 Maikel C. Rheinstädter , Tilo Seydel , Franz Demmel , Tim Salditt

Detection and characterization of individual nano-scale particles, virions, and pathogens are of paramount importance to human health, homeland security, diagnostic and environmental monitoring[1]. There is a strong demand for…

Optics · Physics 2011-07-06 Lina He , Sahin Kaya Ozdemir , Jiangang Zhu , Woosung Kim , Lan Yang

When a macroscopic droplet spreads, a thin precursor film of liquid moves ahead of the advancing liquid-solid-vapor contact line. Whereas this phenomenon has been explored extensively for planar solid substrates, its presence in…

Soft Condensed Matter · Physics 2020-12-08 Luisa G. Cencha , Guido Dittrich , Patrick Huber , Claudio L. A. Berli , Raul Urteaga

We study the indentation of a free-standing lipid membrane suspended over a nanopore on a hydrophobic substrate by means of molecular dynamics simulations. We find that in the course of indentation, the membrane bends at the point of…

Soft Condensed Matter · Physics 2011-08-26 Chen-Hsi Huang , Pai-Yi Hsiao , Fan-Gang Tseng , Shih-Kang Fan , Chien-Chung Fu , Rong-Long Pan