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This paper develops new insights into quantitative methods for the validation of computational model prediction. Four types of methods are investigated, namely classical and Bayesian hypothesis testing, a reliability-based method, and an…

Data Analysis, Statistics and Probability · Physics 2012-06-25 You Ling , Sankaran Mahadevan

Suppose that we have two training sequences generated by parametrized distributions $P_{\theta^*}$ and $P_{\xi^*}$, where $\theta^*$ and $\xi^*$ are unknown true parameters. Given training sequences, we study the problem of classifying…

Information Theory · Computer Science 2021-05-04 Shota Saito , Toshiyasu Matsushima

Much of science is (rightly or wrongly) driven by hypothesis testing. Even in situations where the hypothesis testing paradigm is correct, the common practice of basing inferences solely on p-values has been under intense criticism for over…

Methodology · Statistics 2015-12-31 M. J. Bayarri , Daniel J. Benjamin , James O. Berger , Thomas M. Sellke

Estimating the difference between two binomial proportions will be investigated, where Bayesian, frequentist and fiducial (BFF) methods will be considered. Three vague priors will be used, the Jeffreys prior, a divergence prior and the…

Applications · Statistics 2021-11-17 Lizanne Raubenheimer

We study Bayesian discriminative inference given a model family $p(c,\x, \theta)$ that is assumed to contain all our prior information but still known to be incorrect. This falls in between "standard" Bayesian generative modeling and…

Machine Learning · Statistics 2008-11-18 Jarkko Salojärvi , Kai Puolamäki , Eerika Savia , Samuel Kaski

We consider the problem of comparing two Poisson parameters from the Bayesian perspective. Kawasaki and Miyaoka (2012b) proposed the Bayesian index $P(\lambda_1 < \lambda_2 | X_1,X_2)$ and expressed it using the hypergeometric series. In…

Methodology · Statistics 2016-06-07 Masaaki Doi

In this paper we show that there is a link between approximate Bayesian methods and prior robustness. We show that what is typically recognized as an approximation to the likelihood, either due to the simulated data as in the Approximate…

Methodology · Statistics 2020-04-03 Chaitanya Joshi , Fabrizio Ruggeri

The validity of classical hypothesis testing requires the significance level $\alpha$ be fixed before any statistical analysis takes place. This is a stringent requirement. For instance, it prohibits updating $\alpha$ during (or after) an…

Statistics Theory · Mathematics 2026-01-21 Ben Chugg , Tyron Lardy , Aaditya Ramdas , Peter Grünwald

Testing differences between a treatment and control group is common practice in biomedical research like randomized controlled trials (RCT). The standard two-sample t-test relies on null hypothesis significance testing (NHST) via p-values,…

Methodology · Statistics 2020-05-18 Riko Kelter

When assessing the presence of an exposure causal effect on a given outcome, it is well known that classical measurement error of the exposure can reduce the power of a test of the null hypothesis in question, although its type I error rate…

Methodology · Statistics 2016-10-18 Caleb H. Miles , Joel Schwartz , Eric J. Tchetgen Tchetgen

Bayesian design of experiments and sample size calculations usually rely on complex Monte Carlo simulations in practice. Obtaining bounds on Bayesian notions of the false-positive rate and power therefore often lack closed-form or…

Methodology · Statistics 2025-02-06 Riko Kelter , Samuel Pawel

We consider situations in Bayesian analysis where we have a family of priors $\nu_h$ on the parameter $\theta$, where $h$ varies continuously over a space $\mathcal{H}$, and we deal with two related problems. The first involves sensitivity…

Statistics Theory · Mathematics 2012-02-24 Eugenia Buta , Hani Doss

The Bayes factor surface is a new way to present results from experimental searches for new physics. Searches are regularly expressed in terms of phenomenological parameters - such as the mass and cross-section of a weakly interacting…

High Energy Physics - Phenomenology · Physics 2024-04-23 Andrew Fowlie

Testing for a mediation effect is important in many disciplines, but is made difficult - even asymptotically - by the influence of nuisance parameters. Classical tests such as likelihood ratio (LR) and Wald (Sobel) tests have very poor…

Econometrics · Economics 2024-03-05 Grant Hillier , Kees Jan van Garderen , Noud van Giersbergen

Bayes classifiers for functional data pose a challenge. This is because probability density functions do not exist for functional data. As a consequence, the classical Bayes classifier using density quotients needs to be modified. We…

Statistics Theory · Mathematics 2016-05-13 Xiongtao Dai , Hans-Georg Müller , Fang Yao

In Bayesian hypothesis testing, evidence for a statistical model is quantified by the Bayes factor, which represents the relative likelihood of observed data under that model compared to another competing model. In general, computing Bayes…

Computation · Statistics 2021-12-07 Thomas J. Faulkenberry

The two-level normal hierarchical model has played an important role in statistical theory and applications. In this paper, we first introduce a general adjusted maximum likelihood method for estimating the unknown variance component of the…

Methodology · Statistics 2019-01-25 Masayo Y. Hirose , Partha Lahiri

The Bayes factor, the data-based updating factor from prior to posterior odds, is a principled measure of relative evidence for two competing hypotheses. It is naturally suited to sequential data analysis in settings such as clinical trials…

Methodology · Statistics 2026-01-07 Samuel Pawel , Leonhard Held

A common task in high-throughput biology is to test for differences in means between two samples across thousands of features (e.g., genes or proteins), often with only a handful of replicates per sample. Moderated t-tests handle this…

Methodology · Statistics 2025-10-02 Wanyi Ling , Wufang Hong , Nikolaos Ignatiadis

Classical verification of quantum learning allows classical clients to reliably leverage quantum computing advantages by interacting with untrusted quantum servers. Yet, current quantum devices available in practice suffers from a variety…

Quantum Physics · Physics 2024-11-15 Yinghao Ma , Jiaxi Su , Dong-Ling Deng
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