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Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

Quantitative Methods · Quantitative Biology 2009-11-13 Carlos Escudero

Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

Tissues and Organs · Quantitative Biology 2015-12-22 Richard J. McMurtrey

The simulation of growth processes within soft biological tissues is of utmost importance for many applications in the medical sector. Within this contribution we propose a new macroscopic approach fro modelling stress-driven volumetric…

Computational Engineering, Finance, and Science · Computer Science 2022-01-21 L. Lamm , H. Holthusen , T. Brepols , S. Jockenhövel , S. Reese

A growth of malignant neoplasm is considered as a fractional transport approach. We suggested that the main process of the tumor development through a lymphatic net is fractional transport of cells. In the framework of this fractional…

Tissues and Organs · Quantitative Biology 2007-05-23 A. Iomin , S. Dorfman , L. Dorfman

Early diagnosis and noninvasive monitoring of neurological disorders require sensitivity to elusive cellular-level alterations that occur much earlier than volumetric changes observable with the millimeter-resolution of medical imaging…

We develop a minimal model to describe growing dense active matter such as biological tissues, bacterial colonies and biofilms, that are driven by a competition between particle division and steric repulsion. We provide a detailed numerical…

Statistical Mechanics · Physics 2021-01-04 Elsen Tjhung , Ludovic Berthier

A detailed review of the literature for the last 5-10 years on epitaxial growth of graphene is presented. Both experimental and theoretical aspects related to growth on transition metals and on silicon carbide are thoroughly reviewed.…

Materials Science · Physics 2016-02-23 H. Tetlow , J. Posthuma de Boer , I. J. Ford , D. D. Vvedensky , J. Coraux , L. Kantorovich

How far is neuroepithelial cell proliferation in the developing central nervous system a deterministic process? Or, to put it in a more precise way, how accurately can it be described by a deterministic mathematical model? To provide tracks…

Analysis of PDEs · Mathematics 2010-05-04 Jean Clairambault , Vladimir Flores , Benoit Perthame , Melina Rapacioli , Edmundo Rofman , Rafael Verdes

We consider a macroscopic model for the growth of living tissues incorporating pressure-driven dispersal and pressure-modulated proliferation. Assuming a power-law relation between the mechanical pressure and the cell density, the model can…

Analysis of PDEs · Mathematics 2024-03-29 Tomasz Dębiec , Piotr Gwiazda , Błażej Miasojedow , Zuzanna Szymańska

Epitaxial growth methods are a key technology used in producing large-area thin films on substrates but as a result of various factors controlling growth processes the rational optimization of growth conditions is rather difficult.…

Statistical Mechanics · Physics 2019-09-26 Kazuhiko Seki

What are the general principles that allow proper growth of a tissue or an organ? A growing leaf is an example of such a system: it increases its area by orders of magnitude, maintaining a proper (usually flat) shape. How can this be…

Tissues and Organs · Quantitative Biology 2020-05-13 S. Armon , M. Moshe , E. Sharon

This paper describes how realistic neuromorphic networks can have their connectivity properties fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Luciano da F. Costa

Biological nervous systems are created in a fundamentally different way than current artificial neural networks. Despite its impressive results in a variety of different domains, deep learning often requires considerable engineering effort…

Neural and Evolutionary Computing · Computer Science 2023-07-18 Elias Najarro , Shyam Sudhakaran , Sebastian Risi

Artificial neural networks used for reinforcement learning are structurally rigid, meaning that each optimized parameter of the network is tied to its specific placement in the network structure. It also means that a network only works with…

Neural and Evolutionary Computing · Computer Science 2024-05-20 Joachim Winther Pedersen , Erwan Plantec , Eleni Nisioti , Milton Montero , Sebastian Risi

Many physical phenomena occur on domains that grow in time. When the timescales of the phenomena and domain growth are comparable, models must include the dynamics of the domain. A widespread intrinsically slow transport process is…

Statistical Mechanics · Physics 2017-11-01 C. N. Angstmann , B. I. Henry , A. V. McGann

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

Axons are linear processes of nerve cells that can range from a few tens of micrometers up to meters in length. In addition to external cues, the length of an axon is also regulated by unknown internal mechanisms. Molecular motors have been…

Subcellular Processes · Quantitative Biology 2019-05-15 Frederic Folz , Lukas Wettmann , Giovanna Morigi , Karsten Kruse

We propose a variational framework for accretive surface growth driven by an optimality principle. Rather than prescribing a kinetic law, the configuration at each time step is obtained, within a time-discrete setting, as the solution of a…

Mathematical Physics · Physics 2026-05-14 Rohan Abeyaratne , Roberto Paroni , Marco Picchi Scardaoni

To afford flexible behaviour, the brain must build internal representations that mirror the structure of variables in the external world. For example, 2D space obeys rules: the same set of actions combine in the same way everywhere (step…

Neurons and Cognition · Quantitative Biology 2025-03-04 William Dorrell , Peter E. Latham , Timothy E. J. Behrens , James C. R. Whittington

Working in the framework of morphoelasticity, we develop a model of neurite growth in response to elastic deformation. We decompose the applied stretch into an elastic component and a growth component, and adopt an observationally-motivated…

Biological Physics · Physics 2019-12-13 Madeleine Anthonisen , Peter Grutter