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Light scattering is the main limitation for optical imaging. However, light can be focused through or inside turbid media by spatially shaping the incident wavefront. Wavefront shaping is ultimately limited by the available photon budget.…

Instrumentation and Detectors · Physics 2021-03-24 Bahareh Mastiani , Ivo M. Vellekoop

High-resolution tissue imaging is often compromised by sample-induced optical aberrations that degrade resolution and contrast. While wavefront sensor-based adaptive optics (AO) can measure these aberrations, such hardware solutions are…

The resolving ability of widefield fluorescence microscopy is fundamentally limited by out-of-focus background owing to its low axial resolution, particularly for densely labeled biological samples. Although total internal reflection…

Current post-processing techniques in high contrast imaging depend on some source of diversity between the exoplanet signal and the residual star light at that location. The two main techniques are angular differential imaging (ADI), which…

Instrumentation and Methods for Astrophysics · Physics 2016-01-20 Jared R. Males , Ruslan Belikov , Eduardo Bendek

Photoacoustic microscopy with large depth of focus is significant to the biomedical research. The conventional optical-resolution photoacoustic microscope (OR-PAM) suffers from limited depth of field (DoF) since the employed focused…

Image and Video Processing · Electrical Eng. & Systems 2020-09-07 Xianlin Song , Jianshuang Wei , Lingfang Song

The direct detection and imaging of exoplanets requires the use of high-contrast adaptive optics (AO). In these systems quasi-static aberrations need to be highly corrected and calibrated. In order to achieve this, the pupil-modulated…

Instrumentation and Methods for Astrophysics · Physics 2022-05-25 Nicolas Dubost , Nazim Ali Bharmal , Marc Dubbeldam , Richard M. Myers

Context. Solar wavefront sensing has been a challenge for astrophysical instrumentalists, due to the low contrast between the Sun and the sky background compared to night-time observations, which limits the performance of adaptive optics…

Effective and accurate in-vivo diagnosis of retinal pathologies requires high performance imaging devices, combining a large field of view and the ability to discriminate the ballistic signal from the diffuse background in order to provide…

Traditional optical imaging faces an unavoidable trade-off between resolution and depth of field (DOF). To increase resolution, high numerical apertures (NA) are needed, but the associated large angular uncertainty results in a limited…

Adaptive optics is a strategy to compensate for sample-induced aberrations in microscopy applications. Generally, it requires the presence of "guide stars" in the sample to serve as localized reference targets. We describe an implementation…

Reconstruction of multidimensional signals from the samples of their partial derivatives is known to be a standard problem in inverse theory. Such and similar problems routinely arise in numerous areas of applied sciences, including optical…

Numerical Analysis · Computer Science 2015-05-30 Mohammad Rostami , Oleg Michailovich , Zhou Wang

Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…

Based on diffraction theory and the propagation of the light, Fourier optics is a powerful tool allowing the estimation of a visible-range imaging system to transfer the spatial frequency components of an object. The analyses of the imaging…

General Physics · Physics 2018-06-05 Stephane Perrin , Paul Montgomery

An approach reported recently by Alexandrov et al. on optical scatter imaging, termed digital Fourier microscopy (DFM), represents an adaptation of digital Fourier holography to selective imaging of biological matter. Holographic mode of…

Optics · Physics 2007-05-23 K. Y. T. Seet , P. Blazkiewicz , P. Meredith , A. V. Zvyagin

We investigate methods to calibrate the non-common path aberrations at an adaptive optics system having a wavefront-correcting device working at an extremely high resolution (larger than 150x150). We use focal-plane images collected…

Instrumentation and Methods for Astrophysics · Physics 2015-06-22 Visa Korkiakoski , Christoph U. Keller , Niek Doelman , Matthew Kenworthy , Gilles Otten , Michel Verhaegen

The crossed-sine wavefront sensor (WFS) is a pupil plane wavefront sensor that measures the first derivatives of the wavefront. It is made by three main components: a gradient transmission filter (GTF) built from a product of sine functions…

Optical phase conjugation (OPC) is a nonlinear technique used for counteracting wavefront distortions, with various applications ranging from imaging to beam focusing. Here, we present the design of a diffractive wavefront processor to…

Optics · Physics 2024-06-13 Che-Yung Shen , Jingxi Li , Tianyi Gan , Mona Jarrahi , Aydogan Ozcan

State-of-the-art adaptive optics (AO) systems perform non-linear Fourier-type wavefront sensing for real-time corrections of dynamic wavefront aberrations. This general class of sensors uses a filtering mask in the focal plane that converts…

Instrumentation and Methods for Astrophysics · Physics 2025-06-24 Victoria Laidlaw

The highest three-dimensional (3D) resolution possible in in-vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics (AO). However, this combination brings important limitations, such as small…

Medical Physics · Physics 2020-10-21 Jules Scholler , Kassandra Groux , Kate Grieve , Claude Boccara , Pedro Mecê

We present a promising approach to the extremely fast sensing and correction of small wavefront errors in adaptive optics systems. As our algorithm's computational complexity is roughly proportional to the number of actuators, it is…

Instrumentation and Methods for Astrophysics · Physics 2016-11-26 Christoph U. Keller , Visa Korkiakoski , Niek Doelman , Rufus Fraanje , Raluca Andrei , Michel Verhaegen