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The construction of a dendogram on a set of individuals is a key component of a genomewide association study. However even with modern sequencing technologies the distances on the individuals required for the construction of such a…

Combinatorics · Mathematics 2013-03-11 Katharina T. Huber , Andrei-Alin Popescu

A classical result, fundamental to evolutionary biology, states that an edge-weighted tree $T$ with leaf set $X$, positive edge weights, and no vertices of degree 2 can be uniquely reconstructed from the set of leaf-to-leaf distances…

Populations and Evolution · Quantitative Biology 2011-07-15 A. W. M. Dress , K. T. Huber , M. Steel

We address the problem of computing a single linkage dendrogram. A possible approach is to: (i) Form an edge weighted graph $G$ over the data, with edge weights reflecting dissimilarities. (ii) Calculate the MST $T$ of $G$. (iii) Break the…

Data Structures and Algorithms · Computer Science 2019-11-04 Huanbiao Zhu , Werner Stuetzle

It is a classical result that any finite tree with positively weighted edges, and without vertices of degree 2, is uniquely determined by the weighted path distance between each pair of leaves. Moreover, it is possible for a (small) strict…

Combinatorics · Mathematics 2012-09-12 Katharina T. Huber , Mike Steel

We introduce a decomposition method for the distributed calculation of exact Euclidean Minimum Spanning Trees in high dimensions (where sub-quadratic algorithms are not effective), or more generalized geometric-minimum spanning trees of…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-05 Richard Lettich

This paper extends the key concept of persistence within Topological Data Analysis (TDA) in a new direction. TDA quantifies topological shapes hidden in unorganized data such as clouds of unordered points. In the 0-dimensional case the…

Computational Geometry · Computer Science 2020-07-23 Yury Elkin , Vitaliy Kurlin

Computing a Single-Linkage Dendrogram (SLD) is a key step in the classic single-linkage hierarchical clustering algorithm. Given an input edge-weighted tree $T$, the SLD of $T$ is a binary dendrogram that summarizes the $n-1$ clusterings…

Data Structures and Algorithms · Computer Science 2024-05-14 Laxman Dhulipala , Xiaojun Dong , Kishen N Gowda , Yan Gu

We propose unsupervised representation learning and feature extraction from dendrograms. The commonly used Minimax distance measures correspond to building a dendrogram with single linkage criterion, with defining specific forms of a level…

Machine Learning · Computer Science 2023-01-02 Morteza Haghir Chehreghani , Mostafa Haghir Chehreghani

This paper presents new deterministic and distributed low-diameter decomposition algorithms for weighted graphs. In particular, we show that if one can efficiently compute approximate distances in a parallel or a distributed setting, one…

Data Structures and Algorithms · Computer Science 2022-09-07 Václav Rozhoň , Michael Elkin , Christoph Grunau , Bernhard Haeupler

Given a distance matrix consisting of pairwise distances between species, a distance-based phylogenetic reconstruction method returns a tree metric or equidistant tree metric (ultrametric) that best fits the data. We investigate…

Combinatorics · Mathematics 2017-02-20 Daniel Irving Bernstein , Colby Long

It is folklore that tree-width is monotone under taking subgraphs (i.e. injective graph homomorphisms) and contractions (certain kinds of surjective graph homomorphisms). However, although tree-width is obviously not monotone under any…

Combinatorics · Mathematics 2025-06-11 Benjamin Merlin Bumpus , James Fairbanks , Will J. Turner

The modular decomposition of a symmetric map $\delta\colon X\times X \to \Upsilon$ (or, equivalently, a set of symmetric binary relations, a 2-structure, or an edge-colored undirected graph) is a natural construction to capture key features…

Combinatorics · Mathematics 2021-03-12 Carmen Bruckmann , Peter F. Stadler , Marc Hellmuth

There are many results asserting the existence of tree-decompositions of minimal width which still represent local connectivity properties of the underlying graph, perhaps the best-known being Thomas' theorem that proves for every graph $G$…

Combinatorics · Mathematics 2017-03-13 Joshua Erde

A rooted tree $T$ with vertex labels $t(v)$ and set-valued edge labels $\lambda(e)$ defines maps $\delta$ and $\varepsilon$ on the pairs of leaves of $T$ by setting $\delta(x,y)=q$ if the last common ancestor $\text{lca}(x,y)$ of $x$ and…

Combinatorics · Mathematics 2021-07-06 Marc Hellmuth , Mira Michel , Nikolai N. Nøjgaard , David Schaller , Peter F. Stadler

We consider the problem of estimating species trees from unrooted gene tree topologies in the presence of incomplete lineage sorting, a common phenomenon that creates gene tree heterogeneity in multilocus datasets. One popular class of…

Populations and Evolution · Quantitative Biology 2018-12-21 Sebastien Roch

Clustering is a well-known and studied problem, one of its variants, called contiguity-constrained clustering, accepts as a second input a graph used to encode prior information about cluster structure by means of contiguity constraints…

Computation · Statistics 2023-02-27 Etienne Côme

We derive a statistical model for estimation of a dendrogram from single linkage hierarchical clustering (SLHC) that takes account of uncertainty through noise or corruption in the measurements of separation of data. Our focus is on just…

Machine Learning · Statistics 2015-11-26 Dekang Zhu , Dan P. Guralnik , Xuezhi Wang , Xiang Li , Bill Moran

The \emph{distance matrix} of a simple connected graph $G$ is $D(G)=(d_{ij})$, where $d_{ij}$ is the distance between the vertices $i$ and $j$ in $G$. We consider a weighted tree $T$ on $n$ vertices with edge weights are square matrix of…

Combinatorics · Mathematics 2017-10-30 Fouzul Atik , M. Rajesh Kannan , R. B. Bapat

We study distorted metrics on binary trees in the context of phylogenetic reconstruction. Given a binary tree $T$ on $n$ leaves with a path metric $d$, consider the pairwise distances $\{d(u,v)\}$ between leaves. It is well known that these…

Combinatorics · Mathematics 2007-05-23 Elchanan Mossel

Previously, we proposed a physically-inspired method to construct data points into an effective in-tree (IT) structure, in which the underlying cluster structure in the dataset is well revealed. Although there are some edges in the IT…

Machine Learning · Statistics 2015-07-30 Teng Qiu , Yongjie Li
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