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Related papers: Bacterial chemotaxis without gradient-sensing

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We investigate the (reduced) Keller-Segel equations modeling chemotaxis of bio-organisms. We present a formal derivation and partial rigorous results of the blowup dynamics of solution of these equations describing the chemotactic…

Pattern Formation and Solitons · Physics 2014-07-03 S. I. Dejak , D. Egli , P. M. Lushnikov , I. M. Sigal

Simulations are performed to investigate the nonlinear dynamics of a (2+1)-dimensional chemotaxis model of Keller-Segel (KS) type with a logistic growth term. Because of its ability to display auto-aggregation, the KS model has been widely…

Biological Physics · Physics 2011-11-14 S. Banerjee , A. P. Misra , L. Rondoni

To successfully navigate chemical gradients, microorganisms need to predict how the ligand concentration changes in space. Due to their limited size, they do not take a spatial derivative over their body length but rather a temporal…

Molecular Networks · Quantitative Biology 2024-02-09 Age J. Tjalma , Pieter Rein ten Wolde

Experiments of in vitro formation of blood vessels show that cells randomly spread on a gel matrix autonomously organize to form a connected vascular network. We propose a simple model which reproduces many features of the biological…

Statistical Mechanics · Physics 2009-11-10 A. Gamba , D. Ambrosi , A. Coniglio , A. de Candia , S. Di Talia , E. Giraudo , G. Serini , L. Preziosi , F. Bussolino

Eukaryotic cells sense chemical gradients to decide where and when to move. Clusters of cells can sense gradients more accurately than individual cells by integrating measurements of the concentration made across the cluster. Is this…

Cell Behavior · Quantitative Biology 2021-10-22 Emiliano Perez Ipiña , Brian A. Camley

Complex spatial patterns in biological systems often arise through self-organization without a central coordination, guided by local interactions and chemical signaling. In this study, we explore how motility-dependent chemical deposition…

Biological Physics · Physics 2025-04-24 Subhashree Subhrasmita Khuntia , Debasish Chaudhuri , Abhishek Chaudhuri

Many chemotactic bacteria inhabit environments in which chemicals appear as localized pulses and evolve by processes such as diffusion and mixing. We show that, in such environments, physical limits on the accuracy of temporal gradient…

Biological Physics · Physics 2016-01-19 Andrew M. Hein , Douglas R. Brumley , Francesco Carrara , Roman Stocker , Simon A. Levin

The bacterium E. coli maneuvers itself to regions with high chemoattractant concentrations by performing two stereotypical moves: `runs', in which it moves in near straight lines, and `tumbles', in which it does not advance but changes…

Cell Behavior · Quantitative Biology 2007-11-29 Yariv Kafri , Rava Azeredo da Silveira

The behaviour of an organism often reflects a strategy for coping with its environment. Such behaviour in higher organisms can often be reduced to a few stereotyped modes of movement due to physiological limitations, but finding such modes…

Cell Behavior · Quantitative Biology 2013-08-26 Luke Tweedy , Börn Meier , Jürgen Stephan , Doris Heinrich , Robert G. Endres

We study a version of the Keller-Segel model for bacterial chemotaxis, for which exact travelling wave solutions are explicitly known in the zero attractant diffusion limit. Using geometric singular perturbation theory, we construct…

Dynamical Systems · Mathematics 2014-03-12 Kristen Harley , Peter van Heijster , Graeme Pettet

Bacteria aggregate through various intercellular interactions to build biofilms, but the effect of environmental changes thereupon remains largely unexplored. Here, by using an experimental device that overcomes past difficulties, we…

Biological Physics · Physics 2025-03-12 Takuro Shimaya , Kazumasa A. Takeuchi

Microbiology is the science of microbes, particularly bacteria. Many bacteria are motile: they are capable of self-propulsion. Among these, a significant class execute so-called run-and-tumble motion: they follow a fairly straight path for…

Statistical Mechanics · Physics 2012-09-06 M. E. Cates

We investigate single-cell directional sensing from diffusing chemoattractant signals released by a localized source. We focus on the low-concentration regime in which receptor activity is discrete and cellular decisions are made on…

Cell Behavior · Quantitative Biology 2026-03-12 Vincent Fiorino , Sean D. Lawley , Alan E. Lindsay

Living cells are capable of interacting with their environments in a variety of ways, including cell signalling, adhesion, and directed motion. These behaviours are often mediated by receptor molecules embedded in the cell membrane, which…

Biological Physics · Physics 2023-10-17 Hannah Sleath , Bortolo Mognetti , Yuval Elani , Lorenzo Di Michele

Bacteria such as Escherichia coli (E. coli) exhibit biased motion if kept in a spatially non-uniform chemical environment. Here, we bring out unique time-dependent characteristics of bacterial chemotaxis, in response to a diffusing spatial…

Biological Physics · Physics 2018-12-05 Sibendu Samanta , Ritwik Layek , Shantimoy Kar , Sudipta Mukhopadhyay , Suman Chakraborty

A stochastic walker model is proposed to describe the chemotactic guidance of growth cones, i.e. the tips of developing neurites. The model accounts for the influence of both attractive and repulsive chemical cues, which are emitted by the…

Analysis of PDEs · Mathematics 2025-11-04 Noah Geltner , Ansgar Jüngel

In this paper, we focus on the Keller-Segel chemotaxis system in a random heterogeneous domain. We assume that the corresponding diffusion and chemotaxis coefficients are given by stationary ergodic random fields and apply stochastic…

Analysis of PDEs · Mathematics 2016-09-16 Anastasios Matzavinos , Mariya Ptashnyk

The chemotactic network of Escherichia coli has been studied extensively both biophysically and information-theoretically. Nevertheless, the connection between these two aspects is still elusive. In this work, we report such a connection by…

Cell Behavior · Quantitative Biology 2021-03-31 Kento Nakamura , Tetsuya J. Kobayashi

A classical problem describing the collective motion of cells, is the movement driven by consumption/depletion of a nutrient. Here we analyze one of the simplest such model written as a coupled Partial Differential Equation/Ordinary…

Analysis of PDEs · Mathematics 2022-09-02 Pierre-Emmanuel Jabin , Benoît Perthame

Chemotaxis and haptotaxis have been a main theme in the macroscopic study of bacterial and cellular motility. In this work we investigate the influence these processes have on the shape and motility of fast migrating cells. We note that…

Cell Behavior · Quantitative Biology 2016-12-08 Aaron Brunk , Niklas Kolbe , Nikolaos Sfakianakis