English

Percolation, Morphogenesis, and Burgers Dynamics in Blood Vessels Formation

Statistical Mechanics 2009-11-10 v1 Biological Physics Cell Behavior

Abstract

Experiments of in vitro formation of blood vessels show that cells randomly spread on a gel matrix autonomously organize to form a connected vascular network. We propose a simple model which reproduces many features of the biological system. We show that both the model and the real system exhibit a fractal behavior at small scales, due to the process of migration and dynamical aggregation, followed at large scale by a random percolation behavior due to the coalescence of aggregates. The results are in good agreement with the analysis performed on the experimental data.

Keywords

Cite

@article{arxiv.cond-mat/0303468,
  title  = {Percolation, Morphogenesis, and Burgers Dynamics in Blood Vessels Formation},
  author = {A. Gamba and D. Ambrosi and A. Coniglio and A. de Candia and S. Di Talia and E. Giraudo and G. Serini and L. Preziosi and F. Bussolino},
  journal= {arXiv preprint arXiv:cond-mat/0303468},
  year   = {2009}
}

Comments

4 pages, 11 eps figures