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Related papers: Bacterial chemotaxis without gradient-sensing

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A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

Biological Physics · Physics 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

The response of microbes to external signals is mediated by biochemical networks with intrinsic time scales. These time scales give rise to a memory that impacts cellular behaviour. Here we study theoretically the role of cellular memory in…

Biological Physics · Physics 2020-02-14 Adam Gosztolai , Mauricio Barahona

Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the…

Biological Physics · Physics 2020-07-23 Luis Gómez Nava , Robert Großmann , Marius Hintsche , Carsten Beta , Fernando Peruani

Accurate gradient sensing is crucial for efficient chemotaxis in noisy environments, but the relationship between cell shape deformations and sensing accuracy is not well understood. Using a theoretical framework based on maximum likelihood…

Biological Physics · Physics 2025-03-07 Daiqiu Mou , Yuansheng Cao

A three-dimensional hydrodynamical model for a micro random walker is combined with the idea of chemotactic signaling network of E. coli. Diffusion exponents, orientational correlation functions and their dependence on the geometrical and…

Soft Condensed Matter · Physics 2014-10-02 H. Mohammady , B. Esckandariun , A. Najafi

The signaling apparatus mediating bacterial chemotaxis can adapt to a wide range of persistent external stimuli. In many cases, the bacterial activity returns to its pre-stimulus level exactly and this "perfect adaptability" is robust…

Biological Physics · Physics 2017-10-16 Bernardo A. Mello , Yuhai Tu

In this paper, we derive a new chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the…

Analysis of PDEs · Mathematics 2023-07-19 Tianyuan Xu , Shanming Ji , Chunhua Jin , Ming Mei , Jingxue Yin

In active matter, the lack of momentum conservation makes non-reciprocal interactions the rule rather than the exception. They lead to a rich set of emerging behaviors that are hard to account for and to predict starting from the…

Statistical Mechanics · Physics 2024-02-06 Alberto Dinelli , Jérémy O'Byrne , Agnese Curatolo , Yongfeng Zhao , Peter Sollich , Julien Tailleur

We propose two nonlinear random walk models which are suitable for the analysis of both chemotaxis and anomalous transport. We derive the balance equations for the population density for the case when the transition rate for a random walk…

Statistical Mechanics · Physics 2010-10-22 Sergei Fedotov

As a class of nonlinear partial differential equations, the Keller-Segel system is widely used to model chemotaxis in biology. In this paper, we present the construction and analysis of a decoupled linear, mass-conservative, block-centered…

Numerical Analysis · Mathematics 2025-01-24 Jie Xu , Hongfei Fu

We study a system of two coupled nonlinear parabolic equations. It constitutes a variant of the Keller-Segel model for chemotaxis, i.e. it models the behaviour of a population of bacteria that interact by means of a signalling substance. We…

Analysis of PDEs · Mathematics 2015-05-14 Jonathan Zinsl , Daniel Matthes

Cells move differently on substrates with different elasticities. In particular, the persistence time of their motion is higher on stiffer substrates. We show that this behavior will result in a net transport of cells directed up a…

Biological Physics · Physics 2017-03-09 Elizaveta A. Novikova , Matthew Raab , Dennis E. Discher , Cornelis Storm

E. coli chemotactic motion in the presence of a chemoattractant field has been extensively studied using wet laboratory experiments, stochastic computational models as well as partial differential equation-based models (PDEs). The most…

Quantitative Methods · Quantitative Biology 2022-08-26 Yorgos M. Psarellis , Seungjoon Lee , Tapomoy Bhattacharjee , Sujit S. Datta , Juan M. Bello-Rivas , Ioannis G. Kevrekidis

Eukaryotic cells respond to a chemoattractant gradient by forming intracellular gradients of signaling molecules that reflect the extracellular chemical gradient - an ability called directional sensing. Quantitative experiments have…

Cell Behavior · Quantitative Biology 2017-02-08 Keita Kamino , Yohei Kondo

In this study, we analyse a high-frequency movement dataset for a group of grazing cattle and investigate their spatiotemporal patterns using a simple two-state `stop-and-move' mobility model. We find that the dispersal kernel in the moving…

Quantitative Methods · Quantitative Biology 2016-03-18 Kun Zhao , Raja Jurdak

While microscopic organisms can use gradient-based search to locate resources, this strategy can be poorly suited to the sensory signals available to macroscopic organisms. We propose a framework that models search-decision making in cases…

Populations and Evolution · Quantitative Biology 2015-06-04 Andrew M. Hein , Scott A. McKinley

Single enzyme chemotaxis is a phenomenon by which a non-equilibrium spatial distribution of an enzyme is created and maintained by concentration gradients of the substrate and product of the catalyzed reaction. These gradients can arise…

Soft Condensed Matter · Physics 2022-06-14 Niladri Sekhar Mandal , Ayusman Sen , R. Dean Astumian

We present a new algorithm based on a Cartesian mesh for the numerical approximation of kinetic models for chemosensitive movements set in an arbitrary geometry. We investigate the influence of the geometry on the collective behavior of…

Numerical Analysis · Mathematics 2013-03-12 Francis Filbet , Chang Yang

Chemotaxis of the bacterium Escherichia coli is well understood in shallow chemical gradients, but its swimming behavior remains difficult to interpret in steep gradients. By focusing on single-cell trajectories from simulations, we…

Cell Behavior · Quantitative Biology 2018-02-14 Gabriele Micali , Remy Colin , Victor Sourjik , Robert G. Endres

Bacterial chemotaxis is controlled by the conformational changes of the receptors, in response to the change of the ambient chemical concentration. In a statistical mechanical approach, the signalling due to the conformational changes is a…

Biological Physics · Physics 2009-11-07 Yu Shi