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Enzyme-substrate kinetics form the basis of many biomolecular processes. The interplay between substrate binding and substrate geometry can give rise to long-range interactions between enzyme binding events. Here, we study a general model…

Biological Physics · Physics 2024-01-19 Fabrizio Olmeda , Steffen Rulands

We report measurements on ultrasonic systems analogous to random lasers. One system entails unstable ultrasonic feedback between distinct transducers, another involves a piezoelectric device that emits spontaneously and by stimulation. Both…

Classical Physics · Physics 2017-08-23 Richard L Weaver , Oleg I Lobkis , Alexey Yamilov

A low-power wearable wireless sensor measuring both molecular biomarkers and physiological signals is proposed, where the former are measured by a microfluidic biosensing system while the latter are measured electrically. The low-power…

Signal Processing · Electrical Eng. & Systems 2019-07-04 Xueyuan Zhao , Vidyasagar Sadhu , Tuan Le , Dario Pompili , Mehdi Javanmard

We develop a family of expanded mixed Multiscale Finite Element Methods (MsFEMs) and their hybridizations for second-order elliptic equations. This formulation expands the standard mixed Multiscale Finite Element formulation in the sense…

Numerical Analysis · Mathematics 2012-05-22 Lijian Jiang , Dylan Copeland , J. David Moulton

In order to enhance the robustness and the energy range of efficiency of targeted energy transfer (TET) phenomena in acoustics, we discuss in this paper about the use of multiple nonlinear membrane absorbers in parallel. We show this way,…

Classical Physics · Physics 2014-07-21 Romain Bellet , Bruno Cochelin , Renaud Côte , Pierre-Olivier Mattei

Experimental and numerical investigation of single-beam and pump-probe interaction with a resonantly absorbing dense extended medium under strong and weak field-matter coupling is presented. Significant probe beam amplification and conical…

The Filament Based Lamellipodium Model (FBLM) is a two-phase two-dimensional continuum model, describing the dynamcis of two interacting families of locally parallel actin filaments (C.Schmeiser and D.Oelz, How do cells move? Mathematical…

Cell Behavior · Quantitative Biology 2015-02-10 Angelika Manhart , Christian Schmeiser , Nikolaos Sfakianakis , Dietmar Oelz

Scaling analysis exploiting timescale separation has been one of the most important techniques in the quantitative analysis of nonlinear dynamical systems in mathematical and theoretical biology. In the case of enzyme catalyzed reactions,…

Quantitative Methods · Quantitative Biology 2023-03-21 Justin Eilertsen , Wylie Stroberg , Santiago Schnell

Artificial bilayer lipid membranes (BLMs), along with patch-clamped membranes, are frequently used for functional analyses of membrane proteins. In both methods, the electric properties of membranes are characterized by only one parameter,…

Second-generation sequencing technologies have replaced array-based technologies and become the default method for genomics and epigenomics analysis. Second-generation sequencing technologies sequence tens of millions of DNA/cDNA fragments…

Methodology · Statistics 2017-02-08 Ping Ma , Nan Zhang , Jianhua Z. Huang , Wenxuan Zhong

Traditional system identification with multisine inputs relies on uniform sampling and periodic excitation to preserve Fourier orthogonality and avoid spectral leakage, limiting its use in scenarios with irregular sampling or nonperiodic…

Systems and Control · Electrical Eng. & Systems 2026-05-14 Enrico Dozzi , Tom Oomen , Rodrigo A. González

In this paper, we present a new multiscale method which is capable of coupling atomistic and continuum domains for high frequency wave propagation analysis. The problem of non-physical wave reflection, which occurs due to the change in…

Computational Physics · Physics 2014-08-08 Amit K. Patra , S. Gopalakrishnan , Ranjan Ganguli

We report on a traceable calibration system for a 3500mm-long console that carries a measurement system for inspecting the diameter of a circular reactor chassis. The system uses two single-pass laser interferometers with homodyne fringe…

Instrumentation and Detectors · Physics 2019-05-03 Simon Rerucha , Bretislav Mikel , Zdenek Matej , Ondrej Herman , Miroslava Hola , Michal Jelinek , Petr Jedlicka , Ondrej Cip , Josef Lazar

Nonlinear dynamic models are widely used for characterizing functional forms of processes that govern complex biological pathway systems. Over the past decade, validation and further development of these models became possible due to data…

Methodology · Statistics 2019-08-13 Itai Dattner , Shota Gugushvili , Harold Ship , Eberhard O. Voit

Biomedical and biochemical processes in paper-based microfluidic devices often deal with mixing of two analytes to perform important functions. Uniform mixing of analytes in paper matrix is a challenging proposition, often necessitating…

The structure of membrane-active peptides and their interaction with lipid bilayers can be studied in oriented lipid membranes deposited on solid substrates. Such systems are desirable for a number of surface-sensitive techniques. Here we…

Soft Condensed Matter · Physics 2015-04-10 Chenghao Li , Doru Constantin , Tim Salditt

The elastic properties of a self-assembled bilayer membrane are studied using the self-consistent field theory, applied to a model system composed of flexible amphiphilic chains dissolved in hydrophilic polymeric solvents. Examining the…

Biological Physics · Physics 2013-07-19 Jianfeng Li , Kyle A. Pastor , An-Chang Shi , Friederike Schmid , Jiajia Zhou

Applications of structural equation models (SEMs) are often restricted to linear associations between variables. Maximum likelihood (ML) estimation in non-linear models may be complex and require numerical integration. Furthermore, ML…

Methodology · Statistics 2019-03-15 Klaus Kähler Holst , Esben Budtz-Jørgensen

The connection between domain relaxations at individual scales and the collective heterogeneous response in non-equilibrium systems is a topic of profound interest in recent times. In a model sys- tem of constantly driven oppositely charged…

Soft Condensed Matter · Physics 2016-12-16 Suman Dutta

We present a lithium niobate multi-functional platform (LN-MFP) that integrates photoacoustic and thermoelastic spectroscopy with photodetection on a single chip. Utilizing LN's piezoelectric and thermoelastic properties and an optimized…

Optics · Physics 2025-06-02 Haoyang Lin , Wenguo Zhu , Yongchun Zhong , Huihui Lu , Jianhui Yu , Huadan Zheng