Related papers: Extended Linear Response for Bioanalytical Applica…
In biomedical studies it is common to collect data on multiple biomarkers during study follow-up for dynamic prediction of a time-to-event clinical outcome. The biomarkers are typically intermittently measured, missing at some event times,…
A novel two-leaflet description of lipid membranes is proposed. Within its framework, phase separation phenomena in multicomponent biological membranes are analyzed. As we show, interactions between the leaflets tend to suppress macroscopic…
A natural extension of the descriptors used in the Spectral Neighbor Analysis Potential (SNAP) method is derived to treat atomic interactions in chemically complex systems. Atomic environment descriptors within SNAP are obtained from a…
Active Plasma Resonance Spectroscopy (APRS) is a well known diagnostic method, where a radio frequency probe is immersed into a plasma and excites plasma oscillations. The response of the plasma is recorded as frequency dependent spectrum,…
Motivation: We investigate whether a template-based classification pipeline could be used to identify immunophenotypes in (and thereby classify) a heterogeneous disease with many subtypes. The disease we consider here is Acute Myeloid…
The joint modeling of longitudinal and time-to-event data is an important tool of growing popularity to gain insights into the association between a biomarker and an event process. We develop a general framework of flexible additive joint…
Optical fiber multi parameter sensing is fundamentally constrained by cross-sensitivity and the complexity of multi sensor integration. Here, we present a dual-dip heterogeneous long-period fiber grating (LPFG) sensing platform enabled by…
In this paper, a two-step strategy for parametric sensitivity analysis for such systems is proposed, exploiting advantages and synergies between two recently proposed sensitivity analysis methodologies for stochastic dynamics. The first…
The advent in recent years of highly parallelized microfluidic chemical reaction systems necessitates an understanding of all fluid dynamic time scales including the often neglected millisecond time scale of the inertia of the liquid. We…
Exploring new target schemes for laser wakefield accelerators is essential to meet the challenge of increasing repetition rates while ensuring stability and quality of the produced electron beams. The prototyping of a two-chamber gas cell…
Cells can use periodic enzyme activities to adapt to periodic environments or existing internal rhythms and to establish metabolic cycles that schedule biochemical processes in time. A periodically changing allocation of the protein budget…
The elastic properties of two-component bilayer membranes are studied using a coarse grain model for amphiphilic molecules. The two species of amphiphiles considered here differ only in their length. Molecular Dynamics simulations are…
This paper presents a physics-consistent framework for bistatic sensing incorporating a 2-Dimensional (2D) waveguide-fed metasurface antenna array capable of realizing eXtremely-Large Multiple-Input Multiple-Output (XL MIMO) apertures. A…
Nonperturbative approach based on exact solution of Boltzmann kinetic equation in the relaxation time approximation is developed for the study of nonlinear response of electron-doped few-layer graphene to a high-frequency electromagnetic…
How atoms and electrons in a molecule move during a chemical reaction and how rapidly energy is transferred to or from the surroundings can be studied with flashes of laser light. However, despite prolonged efforts to develop various…
Logistic regression with unknown sizes has many important applications in biological and medical sciences. All models about this problem in the literature are parametric ones. A semiparametric regression model is proposed. This model…
The nonlinear optical response of materials to exciting light is enhanced by resonances between the incident laser frequencies and the energy levels of the excited material. Traditionally, in molecular nonlinear spectroscopy one tunes the…
Cultivating oleaginous microalgae in specific culturing devices such as raceways is seen as a future way to produce biofuel. The complexity of this process coupling non linear biological activity to hydrodynamics makes the optimization…
Bipolar nanoporous membranes and bipolar nanochannels are used in water desalination and energy-harvesting systems that provide clean water and green energy, respectively. The growing need for both requires continuous improvement of their…
Fluorescence Lifetime Imaging Microscopy (FLIM) using multiphoton excitation techniques is now finding an important place in quantitative imaging of protein-protein interactions and intracellular physiology. We review here the recent…