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We have evaluated the imaging capabilities of the Timepix4 hybrid silicon pixel detector for 100 keV and 200 keV electrons in a Transmission Electron Microscope (TEM). Using the knife-edge method, we have measured the Modulation Transfer…

A foil-microchannel plate (MCP) detector, which uses electrostatic lenses and possesses both good position and timing resolutions, has been designed and simulated for beam diagnostics and mass measurements at the next-generation…

Instrumentation and Detectors · Physics 2021-06-01 un-hao Liu , Zhuang Ge , Qian Wang , Geng Wang , Li-na Sheng , Wen-wen Ge , Xing Xu , Peng Shuai , Qi Zeng , Bo Wu

The main challenges posed by the design of future Positron Emission Tomography machines are the improvement of the spatial and timing resolution and the combined operation with magnetic resonance. The Micro Pixel Photon Counter by Hamamatsu…

Medical Physics · Physics 2008-05-06 N. D'Ascenzo , E. Garutti , M. Goettlich , H. C. Schultz-Coulon , A. Tadday

CMOS sensors were successfully implemented in the STAR tracker [1]. LHC experiments have shown that efficient b tagging, reconstruction of displaced vertices and identification of disappearing tracks are necessary. An improved vertex…

Instrumentation and Detectors · Physics 2021-05-21 Nicolas T. Fourches , Geraldine Hallais , Charles Renard

Direct electron detection is currently revolutionizing many fields of electron microscopy due to its lower noise, its reduced point-spread function, and its increased quantum efficiency. More specifically to this work, Timepix3 is a…

Instrumentation and Detectors · Physics 2023-12-21 Yves Auad , Jassem Baaboura , Jean-Denis Blazit , Marcel Tencé , Odile Stéphan , Mathieu Kociak , Luiz H. G. Tizei

Hybrid pixel detectors have a well-established array of applications ranging from particle physics to life sciences. The small dimensions of Timepix3 as well as its relatively low energetic expenses make it an intriguing option additionally…

Instrumentation and Detectors · Physics 2025-09-10 Radu-Emanuel Mihai , Benedikt Bergmann , Petr Smolyanskiy

With the development of high repetition rate laser sources and advanced multi-particle correlation analyses such as covariance mapping, particle detection techniques such as velocity map imaging (VMI) are poised to offer unprecedented views…

Instrumentation and Detectors · Physics 2026-03-06 Ian Gabalski , Eleanor Weckwerth , Chuan Cheng , Philip H. Bucksbaum

Multiphoton microscopy is widely used for live imaging. However, its acquisition speed remains limited by fluorophore emission rates and photodamage. To increase the pixel rate of a two-photon microscope beyond a few megahertz (MHz),…

Imaging across both the full transverse spatial and temporal dimensions of a scene with high precision in all three coordinates is key to applications ranging from LIDAR to fluorescence lifetime imaging. However, compromises that sacrifice,…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 C. Callenberg , A. Lyons , D. den Brok , A. Fatima , A. Turpin , V. Zickus , L. Machesky , J. Whitelaw , D. Faccio , M. B. Hullin

We present a comprehensive characterization of the LAPPD Gen-II, a large-area microchannel-plate photomultiplier tube (MCP-PMT) equipped with a capacitively coupled sensing (readout) electrode. Two detector variants with different…

Instrumentation and Detectors · Physics 2025-12-03 S. Korpar , R. Dolenec , F. Grijalva , A. Lozar , A. Kodrič , P. Križan , S. Parashari , R. Pestotnik , A. Seljak , D. Žontar

A 760 $\times$ 760 $\times$ 30 mm$^3$ plastic scintillation detector viewed by photomultiplier tubes (PMTs) from four corners has been developed, and the detector has been tested with cosmic rays and $\gamma$ rays. A position-independent…

Instrumentation and Detectors · Physics 2016-08-03 Shu-wen Tang , Yu-hong Yu , Yong Zhou , Zhi-yu Sun , Xue-heng Zhang , Shi-tao Wang , Ke Yue , Long-xiang Liu , Fang Fang , Duo Yan , Yu Sun , Zhao-min Wang

Timepix and Timepix3 are hybrid pixel detectors ($256\times 256$ pixels), capable of tracking ionizing particles as isolated clusters of pixels. To efficiently analyze such clusters at potentially high rates, we introduce multiple…

Data Analysis, Statistics and Probability · Physics 2019-11-07 Petr Mánek , Benedikt Bergmann , Petr Burian , Lukáš Meduna , Stanislav Pospíšil , Michal Suk

Hyperspectral imaging provides high-dimensional spatial-temporal-spectral information revealing intrinsic matter characteristics. Here we report an on-chip computational hyperspectral imaging framework with high spatial and temporal…

We introduce a imaging modality that works by transiently masking image-subregions during a single exposure of a CCD frame. By offsetting subregion exposure time, temporal information is embedded within each stored frame, allowing…

Quantitative Methods · Quantitative Biology 2016-09-08 Gil Bub , Matthias Tecza , Michiel Helmes , Peter Lee , Peter Kohl

A novel gaseous two-dimensional imaging detector "Micro Pixel Chamber (micro-PIC)" has been developed. This detector is based on double sided printed circuit board (PCB). We have developed large area (10cm x 10cm) micro-PICs with 65536…

High Energy Physics - Experiment · Physics 2015-06-25 T. Nagayoshi , H. Kubo , K. Miuchi , A. Ochi , R. Orito , A. Takada , T. Tanimori , M. Ueno

The combination of Micro-Pattern Gaseous Detectors (MPGDs) and pixel charge readout enables specific experimental opportunities. Using the Timepix4 for the readout is advantageous because of its size (around 7 cm^2 active area) and its…

We report the first characterization results of an optical time-stamping camera based on the Timepix4 chip coupled to a fully depleted optical silicon sensor and fast image intensifier, enabling sub-nanosecond scale, time-resolved imaging…

Future astrophysics and cosmic microwave background space missions operating in the far-infrared to millimetre part of the spectrum will require very large arrays of ultra-sensitive detectors in combination with high multiplexing factors…

Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the…

Instrumentation and Detectors · Physics 2013-06-05 Donald F. Smith , Andras Kiss , Franklin E. Leach , Errol W. Robinson , Ljiljana Paša-Tolić , Ron M. A. Heeren

Test measurements on the silicon pixel detector for the beam trajectory monitor at the free electron laser of the TESLA test facility are presented. To determine the electronic noise of detector and read-out and to calibrate the signal…