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The flagellated bacterium Escherichia coli is increasingly used experimentally as a self-propelled swimmer. To obtain meaningful, quantitative results that are comparable between different laboratories, reproducible protocols are needed to…
The flexibility of the bacterial flagellar hook is believed to have substantial consequences for microorganism locomotion. Using a simplified model of a rigid flagellum and a flexible hook, we show that the paths of axisymmetric cell bodies…
\textit{Plasmodium vivax} is the most geographically widespread malaria-causing parasite resulting in significant associated global morbidity and mortality. One of the factors driving this widespread phenomenon is the ability of the…
Intrinsically disordered proteins (IDPs), such as amyloid polypeptide (IAPP), beta-amyloid (A\b{eta}), and {\alpha}-synuclein are linked to the insurgence of type 2 diabetes, Alzheimer's, and Parkinson's diseases, respectively. Common…
Ciliated microorganisms near the base of the aquatic food chain either swim to encounter prey or attach at a substrate and generate feeding currents to capture passing particles. Here, we represent attached and swimming ciliates using a…
Inspired by recent suggestions that the Alzheimer's amyloid beta peptide (A beta) can insert into cell membranes and form harmful ion channels, we model insertion of the 40 and 42 residue forms of the peptide into cell membranes using a…
Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a…
Toxoplasma gondii is the causative agent responsible for toxoplasmosis and serves as one of the most common parasites in the world. For a successful lytic cycle, T. gondii must traverse biological barriers in order to invade host cells, and…
According to the World Health Organization(WHO), malaria is estimated to have killed 627,000 people and infected over 241 million people in 2020 alone, a 12% increase from 2019. Microscopic diagnosis of blood cells is the standard testing…
Cholesterol (CHOL) drives lipid segregation and is thus a key player for the formation of lipid rafts and followingly for the ability of a cell to, e.g., enable selective agglomeration of proteins. The lipid segregation is driven by…
In the mammalian plasma membrane, cholesterol can translocate rapidly between the exoplasmic and cytoplasmic leaves, so that its distribution between them should be given by the equality of its chemical potential in the leaves. Due to its…
Electrical activity of fungus \emph{Pleurotus ostreatus} is characterised by slow (hours) irregular waves of baseline potential drift and fast (minutes) action potential likes spikes of the electrical potential. An exposure of the mycelium…
Most bacteria swim through fluids by rotating helical flagella which can take one of twelve distinct polymorphic shapes. The most common helical waveform is the "normal" form, used during forward swimming runs. To shed light on the…
Fibronectin, a glycoprotein secreted by connective tissue cells is found in the human plasma as well as in the ECM. It is known to have an adhesive property and plays a role in cell-to-cell and cell-to-substratum adhesions. In rheumatoid…
Sterols have been ascribed a major role in the organization of biological membranes, in particular for the formation of liquid ordered domains in complex lipid mixtures. Here, we employed molecular dynamics simulations to compare the…
Antimicrobial resistance (AMR) poses a significant threat to public health by increasing mortality, extending hospital stays, and increasing healthcare costs. It affects people of all ages and affects health services, veterinary medicine,…
The need to develop new methods for the high-sensitivity diagnosis of malaria has initiated a global activity in medical and interdisciplinary sciences. Most of the diverse variety of emerging techniques are based on research-grade…
Swimming organisms in their natural habitat navigate through a wide array of geometries and chemical environments. Interaction with the boundaries is ubiquitous and can significantly modify the swimming characteristics of the organism as…
Giardia lamblia is a flagellate intestinal protozoan with global distribution causing the disease known as giardiasis. This parasite is responsable for 35.1% of outbreaks of diarrhea caused by contaminated water which and mainly affects…
This paper investigates the deterministic extinction and permanence of a family of SEIRS malaria models with multiple random delays, and with a general nonlinear incidence rate. The conditions for the extinction and permanence of the…