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The nematode Caenorhabditis elegans, with information on neural connectivity, three-dimensional position and cell linage provides a unique system for understanding the development of neural networks. Although C. elegans has been widely…

Biological Physics · Physics 2011-01-17 Sreedevi Varier , Marcus Kaiser

A central problem of neuroscience involves uncovering the principles governing the organization of nervous systems which ensure robustness in brain development. The nematode Caenorhabditis elegans provides us with a model organism for…

Neurons and Cognition · Quantitative Biology 2020-07-01 Anand Pathak , Nivedita Chatterjee , Sitabhra Sinha

Most social, technological and biological networks are embedded in a finite dimensional space, and the distance between two nodes influences the likelihood that they link to each other. Indeed, in social systems, the chance that two…

Physics and Society · Physics 2018-06-27 Paul Balister , Chaoming Song , Oliver Riordan , Bela Bollobas , Albert-Laszlo Barabasi

It is now generally assumed that the heterogeneity of most networks in nature probably arises via preferential attachment of some sort. However, the origin of various other topological features, such as degree-degree correlations and…

Adaptation and Self-Organizing Systems · Physics 2010-03-05 Samuel Johnson , J. Marro , Joaquin J. Torres

The organization of interactions in complex systems can be described by networks connecting different units. These graphs are useful representations of the local and global complexity of the underlying systems. The origin of their…

Physics and Society · Physics 2015-09-30 Luís F Seoane , Ricard Solé

To find out the role of the wiring cost in the organization of the neural network of the nematode \textit{Caenorhapditis elegans} (\textit{C. elegans}), we build the neuronal map of \textit{C. elegans} based on geometrical positions of…

Neurons and Cognition · Quantitative Biology 2009-11-11 Yong-Yeol Ahn , Beom Jun Kim , Hawoong Jeong

The stochastic exploration of the configuration space and the exploitation of functional states underlie many biological processes. The evolutionary dynamics stands out as a remarkable example. Here, we introduce a novel formalism that…

Biological Physics · Physics 2024-01-23 Vito Dichio , Fabrizio De Vico Fallani

Complex systems are very often organized under the form of networks where nodes and edges are embedded in space. Transportation and mobility networks, Internet, mobile phone networks, power grids, social and contact networks, neural…

Statistical Mechanics · Physics 2015-05-20 Marc Barthelemy

Neural networks show a progressive increase in complexity during the time course of evolution. From diffuse nerve nets in Cnidaria to modular, hierarchical systems in macaque and humans, there is a gradual shift from simple processes…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser , Sreedevi Varier

Probing the developing neural circuitry in Caenorhabditis elegans has enhanced our understanding of nervous systems. The C. elegans connectome, like those of other species, is characterized by a rich club of densely connected neurons…

Neurons and Cognition · Quantitative Biology 2021-08-26 Alec Helm , Ann S. Blevins , Danielle S. Bassett

Early brain connectivity development consists of multiple stages: birth of neurons, their migration and the subsequent growth of axons and dendrites. Each stage occurs within a certain period of time depending on types of neurons and…

Neurons and Cognition · Quantitative Biology 2015-03-16 Sol Lim , Marcus Kaiser

The neural dynamics of the nematode C. elegans are experimentally low-dimensional and correspond to discrete behavioral states, where previous modeling work has found neural proxies for some of these states. Experimental results further…

Neurons and Cognition · Quantitative Biology 2015-09-04 James Kunert , Eli Shlizerman , Andrew Walker , J. Nathan Kutz

The nervous system of the nematode soil worm Caenorhabditis elegans exhibits remarkable complexity despite the worm's small size. A general challenge is to better understand the relationship between neural organization and neural activity…

Neurons and Cognition · Quantitative Biology 2020-10-30 Alejandro Morales , Tom Froese

Complex networks can often be decomposed into less complex sub-networks whose structures can give hints about the functional organization of the network as a whole. However, these structural motifs can only tell one part of the functional…

Molecular Networks · Quantitative Biology 2015-05-20 Jifeng Qian , Arend Hintze , Christoph Adami

One of the biggest challenges in biology is to understand how activity at the cellular level of neurons, as a result of their mutual interactions, leads to the observed behavior of an organism responding to a variety of environmental…

Neurons and Cognition · Quantitative Biology 2010-03-09 Raj Kumar Pan , Nivedita Chatterjee , Sitabhra Sinha

Molecular networks act as the backbone of cellular activities, providing an {excellent} opportunity to understand the developmental changes in an organism. While network data usually constitute only stationary network graphs, constructing…

Molecular Networks · Quantitative Biology 2016-02-29 Pramod Shinde , Sarika Jalan

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

For many networks, the connection pattern (often called the topology) can vary in time, depending on the changing state, or mode, of the modules within the network. For example, "airplane mode" is the name for one communicative mode of a…

Dynamical Systems · Mathematics 2015-12-15 David I. Spivak , Joshua Z. Tan

Networks in nature are often formed within a spatial domain in a dynamical manner, gaining links and nodes as they develop over time. We propose a class of spatially-based growing network models and investigate the relationship between the…

Physics and Society · Physics 2013-12-30 Ari Zitin , Alex Gorowora , Shane Squires , Mark Herrera , Thomas M. Antonsen , Michelle Girvan , Edward Ott

We study an abstracted model of neuronal activity via numerical simulation, and report spatiotemporal pattern formation and critical like dynamics. A population of pulse coupled, discretised, relaxation oscillators is simulated over…

Neurons and Cognition · Quantitative Biology 2019-04-24 Dionysios Georgiadis , Didier Sornette
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