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In this paper, we propose a mass conservative semi-Lagrangian finite difference scheme for multi-dimensional problems without dimensional splitting. The semi-Lagrangian scheme, based on tracing characteristics backward in time from grid…

Numerical Analysis · Mathematics 2016-07-26 Tao Xiong , Giovanni Russo , Jing-Mei Qiu

We present an efficient and robust numerical model for simulation of electrokinetic phenomena in porous networks over a wide range of applications including energy conversion, desalination, and lab-on-a-chip systems. Coupling between fluid…

Fluid Dynamics · Physics 2016-10-04 Shima Alizadeh , Ali Mani

In this paper, a two-dimensional incompressible miscible displacement model is considered, and a novel decoupled and linearized high-order finite difference scheme is developed, by utilizing the multi-time-step strategy to treat the…

Numerical Analysis · Mathematics 2025-08-05 Xiaoying Wang , Hongxing Rui , Hongfei Fu

We develop a simple model of ionic current through neuronal membranes as a function of membrane potential and extracellular ion concentration. The model combines a simplified Poisson-Nernst-Planck (PNP) model of ion transport through…

Biological Physics · Physics 2023-09-06 Linda Werneck , Mertcan Han , Erdost Yildiz , Marc-André Keip , Metin Sitti , Michael Ortiz

Stochastic diffusion equations are crucial for modeling a range of physical phenomena influenced by uncertainties. We introduce the generalized finite difference method for solving these equations. Then, we examine its consistency,…

Numerical Analysis · Mathematics 2024-11-22 Faezeh Nassajian Mojarrad

Partial Differential Equations (PDE) are fundamental to model different phenomena in science and engineering mathematically. Solving them is a crucial step towards a precise knowledge of the behaviour of natural and engineered systems. In…

We have developed a molecular mean-field theory -- fourth-order Poisson-Nernst-Planck-Bikerman theory -- for modeling ionic and water flows in biological ion channels by treating ions and water molecules of any volume and shape with…

Soft Condensed Matter · Physics 2020-05-18 Jinn-Liang Liu , Bob Eisenberg

In this work, we derive particle schemes, based on micro-macro decomposition, for linear kinetic equations in the diffusion limit. Due to the particle approximation of the micro part, a splitting between the transport and the collision part…

Numerical Analysis · Mathematics 2017-01-19 Anaïs Crestetto , Nicolas Crouseilles , Mohammed Lemou

We propose a novel projection method that guarantees the conservation of integral quantities in Physics-Informed Neural Networks (PINNs). While the soft constraint that PINNs use to enforce the structure of partial differential equations…

Machine Learning · Computer Science 2026-05-26 Anthony Baez , Wang Zhang , Ziwen Ma , Lam Nguyen , Subhro Das , Luca Daniel

This paper provides mathematical analysis of an elementary fully discrete finite difference method applied to inhomogeneous (non-constant density and viscosity) incompressible Navier-Stokes system on a bounded domain. The proposed method…

Numerical Analysis · Mathematics 2023-02-28 Kohei Soga

This is an early but comprehensive review of the PNP Poisson Nernst Planck theory of ion channels. Extensive reference is made to the earlier literature. The starting place for this theory of open channels is a theory of electrodiffusion…

Biomolecules · Quantitative Biology 2010-09-16 Bob Eisenberg

Continuum models for ion transport through polyamide nanopores require solving partial differential equations (PDEs) through complex pore geometries. Resolving spatiotemporal features at this length and time-scale can make solving these…

Machine Learning · Computer Science 2023-05-03 Danyal Rehman , John H. Lienhard

In this paper, a linearized semi-implicit finite difference scheme is proposed for solving the two-dimensional (2D) space fractional nonlinear Schr\"{o}dinger equation (SFNSE).The scheme has the property of mass and energy conservation on…

Numerical Analysis · Mathematics 2021-07-27 Hongling Hu , Xianlin Jin , Dongdong He , Kejia Pan , Qifeng Zhang

In this study, we present a novel computational framework that integrates the finite volume method with graph neural networks to address the challenges in Physics-Informed Neural Networks(PINNs). Our approach leverages the flexibility of…

Fluid Dynamics · Physics 2024-05-08 Tianyu Li , Yiye Zou , Shufan Zou , Xinghua Chang , Laiping Zhang , Xiaogang Deng

Charge dynamics play essential role in many practical applications such as semiconductors, electrochemical devices and transmembrane ion channels. A Maxwell-Amp\`{e}re Nernst-Planck (MANP) model that describes charge dynamics via…

Numerical Analysis · Mathematics 2025-06-04 Zhonghua Qiao , Zhenli Xu , Qian Yin , Shenggao Zhou

We propose and analyze volume-preserving parametric finite element methods for surface diffusion, conserved mean curvature flow and an intermediate evolution law in an axisymmetric setting. The weak formulations are presented in terms of…

Numerical Analysis · Mathematics 2022-04-08 Weizhu Bao , Harald Garcke , Robert Nurnberg , Quan Zhao

Multidimensional population balance models (PBMs) describe chemical and biological processes having a distribution over two or more intrinsic properties (such as size and age, or two independent spatial variables). The incorporation of…

Computational Engineering, Finance, and Science · Computer Science 2025-04-29 Pavan Inguva , Richard D. Braatz

Structure-preserving particle methods have recently been proposed for a class of nonlinear continuity equations, including aggregation-diffusion equation in [J. Carrillo, K. Craig, F. Patacchini, Calc. Var., 58 (2019), pp. 53] and the…

Numerical Analysis · Mathematics 2025-06-19 Jingwei Hu , Samuel Q. Van Fleet , Andy T. S. Wan

In this paper, a two-grid method is proposed to linearize and symmetrize the steady-state Poisson-Nernst-Planck equations. The computational system is decoupled to linearize and symmetrize equations by using this method, which can improve…

Numerical Analysis · Mathematics 2017-03-23 Xuefang Li , Ying Yang , Hang Cheng

In multi-phase fluid flow, fluid-structure interaction, and other applications, partial differential equations (PDEs) often arise with discontinuous coefficients and singular sources (e.g., Dirac delta functions). These complexities arise…

Numerical Analysis · Mathematics 2019-07-24 Chung-Nan Tzou , Samuel Stechmann