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We consider the problem of providing optimal uncertainty quantification (UQ) --- and hence rigorous certification --- for partially-observed functions. We present a UQ framework within which the observations may be small or large in number,…

Probability · Mathematics 2016-05-20 T. J. Sullivan , M. McKerns , D. Meyer , F. Theil , H. Owhadi , M. Ortiz

Inverse problems play a key role in modern image/signal processing methods. However, since they are generally ill-conditioned or ill-posed due to lack of observations, their solutions may have significant intrinsic uncertainty. Analysing…

Signal Processing · Electrical Eng. & Systems 2019-09-09 Xiaohao Cai , Marcelo Pereyra , Jason D. McEwen

Uncertainty quantification is a key part of astronomy and physics; scientific researchers attempt to model both statistical and systematic uncertainties in their data as best as possible, often using a Bayesian framework. Decisions might…

Instrumentation and Methods for Astrophysics · Physics 2022-07-29 Peter Hatfield

Within the Heisenberg's uncertainty principle it is explicitly discussed the impact of these inequalities on the theory of integrated photonics at sub-wavelength regime. More especially, the uncertainty of the effective index values in…

Quantum Physics · Physics 2016-04-04 Bruno Bêche , E Gaviot

Diversity indices are useful single-number metrics for characterizing a complex distribution of a set of attributes across a population of interest. The utility of these different metrics or sets of metrics depend on the context and…

Populations and Evolution · Quantitative Biology 2020-03-06 Song Xu , Lucas Böttcher , Tom Chou

The DUCK-calculus presented here is a recent approach to cope with probabilistic uncertainty in a sound and efficient way. Uncertain rules with bounds for probabilities and explicit conditional independences can be maintained incrementally.…

Artificial Intelligence · Computer Science 2013-03-25 Helmut Thone , Ulrich Guntzer , Werner Kiessling

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

The dynamics of single cell migration on flat surfaces is usually modeled by a Langevin-like problem consisting of ballistic motion for short periods and random walk. for long periods. Conversely, recent studies have revealed a previously…

Image-to-image regression is an important learning task, used frequently in biological imaging. Current algorithms, however, do not generally offer statistical guarantees that protect against a model's mistakes and hallucinations. To…

"Back-of-the-envelope" or "rule-of-thumb" calculations involving rough estimates of quantities play a central scientific role in developing intuition about the structure and behaviour of physical systems, for example in so-called `Fermi…

Quantitative Methods · Quantitative Biology 2014-12-05 Iain G. Johnston , Benjamin C. Rickett , Nick S. Jones

Despite differences in brain sizes and cognitive niches among mammals, their cerebral cortices posses many common features and regularities. These regularities have been a subject of experimental investigation in neuroanatomy for the last…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jan Karbowski

Heisenberg's uncertainty principle is usually taken to express a limitation of operational possibilities imposed by quantum mechanics. Here we demonstrate that the full content of this principle also includes its positive role as a…

Quantum Physics · Physics 2007-10-31 P. Busch , T. Heinonen , P. Lahti

Distribution shift is an important concern in deep image classification, produced either by corruption of the source images, or a complete change, with the solution involving domain adaptation. While the primary goal is to improve accuracy…

Machine Learning · Statistics 2021-10-19 Tiago Salvador , Vikram Voleti , Alexander Iannantuono , Adam Oberman

Uncertainty maps highlight unreliable regions in segmentation predictions. However, most uncertainty evaluation metrics treat voxels independently, ignoring spatial context and anatomical structure. As a result, they may assign identical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Tal Zeevi , Eléonore V. Lieffrig , Lawrence H. Staib , John A. Onofrey

The uncertainty principle lies at the heart of quantum physics, and is widely thought of as a fundamental limit on the measurement precisions of incompatible observables. Here we show that the traditional uncertainty relation in fact…

Quantum Physics · Physics 2021-02-03 Jun-Li Li , Cong-Feng Qiao

We present a general framework for uncertainty quantification that is a mosaic of interconnected models. We define global first and second order structural and correlative sensitivity analyses for random counting measures acting on risk…

Probability · Mathematics 2021-01-05 Caleb Deen Bastian , Herschel Rabitz

Computational cardiac modelling is a mature area of biomedical computing, and is currently evolving from a pure research tool to aiding in clinical decision making. Assessing the reliability of computational model predictions is a key…

Computational Physics · Physics 2018-01-10 Rocío Rodríguez-Cantano , Joakim Sundnes , Marie E. Rognes

In this work, we describe a Bayesian framework for reconstructing the boundaries of piecewise smooth regions in the X-ray computed tomography (CT) problem in an infinite-dimensional setting. In addition to the reconstruction, we are also…

Numerical Analysis · Mathematics 2022-12-20 Babak Maboudi Afkham , Yiqiu Dong , Per Christian Hansen

Uncertainty in medical image segmentation is inherently non-uniform, with boundary regions exhibiting substantially higher ambiguity than interior areas. Conventional training treats all pixels equally, leading to unstable optimization…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Jinming Zhang , Youpeng Yang , Xi Yang , Haosen Shi , Yuyao Yan , Qiufeng Wang , Guangliang Cheng , Kaizhu Huang

We propose a new scheme to express the uncertainty principle in form of inequality of the bipartite correlation functions for a given multipartite state, which provides an experimentally feasible and model-independent way to verify various…

Quantum Physics · Physics 2014-03-05 Jun-Li Li , Kun Du , Cong-Feng Qiao
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