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Related papers: SOAP3-dp: Fast, Accurate and Sensitive GPU-based S…

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We present the Scalable Nucleotide Alignment Program (SNAP), a new short and long read aligner that is both more accurate (i.e., aligns more reads with fewer errors) and 10-100x faster than state-of-the-art tools such as BWA. Unlike recent…

Data Structures and Algorithms · Computer Science 2011-11-24 Matei Zaharia , William J. Bolosky , Kristal Curtis , Armando Fox , David Patterson , Scott Shenker , Ion Stoica , Richard M. Karp , Taylor Sittler

Aligning millions of short DNA or RNA reads, of 75 to 250 base pairs each, to a reference genome is a significant computation problem in bioinformatics. We present a flexible and fast FPGA-based short read alignment tool. Our aligner makes…

Genomics · Quantitative Biology 2018-05-02 Nathaniel McVicar , Akina Hoshino , Anna La Torre , Thomas A. Reh , Walter L. Ruzzo , Scott Hauck

The tremdendous advances in high-throughput sequencing technologies have made population-scale sequencing as performed in the 1000 Genomes project and the Genome of the Netherlands project possible. Next-generation sequencing has allowed…

Genomics · Quantitative Biology 2013-03-15 Tobias Marschall , Alexander Schönhuth

The proliferation of high-throughput sequencing machines ensures rapid generation of up to billions of short nucleotide fragments in a short period of time. This massive amount of sequence data can quickly overwhelm today's storage and…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-13 Subho S. Banerjee , Mohamed El-Hadedy , Jong Bin Lim , Zbigniew T. Kalbarczyk , Deming Chen , Steve Lumetta , Ravishankar K. Iyer

We explore different ways to simplify the evaluation of the smooth overlap of atomic positions (SOAP) many-body atomic descriptor [Bart\'{o}k et al., Phys. Rev. B 87, 184115 (2013)]. Our aim is to improve the computational efficiency of…

Computational Physics · Physics 2019-09-16 Miguel A. Caro

With the advance in genome sequencing technology, the lengths of deoxyribonucleic acid (DNA) sequencing results are rapidly increasing at lower prices than ever. However, the longer lengths come at the cost of a heavy computational burden…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-12 Seongyeon Park , Junguk Hong , Jaeyong Song , Hajin Kim , Youngsok Kim , Jinho Lee

We consider the problem of cross-sensor domain adaptation in the context of LiDAR-based 3D object detection and propose Stationary Object Aggregation Pseudo-labelling (SOAP) to generate high quality pseudo-labels for stationary objects. In…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Chengjie Huang , Vahdat Abdelzad , Sean Sedwards , Krzysztof Czarnecki

In this paper we introduce a novel parallel pipeline for fast and accurate mapping of RNA sequences on servers equipped with multicore processors. Our software, named HPG-Aligner, leverages the speed of the Burrows-Wheeler Transform to map…

PPG-based Blood Pressure (BP) estimation is a challenging biosignal processing task for low-power devices such as wearables. State-of-the-art Deep Neural Networks (DNNs) trained for this task implement either a PPG-to-BP signal-to-signal…

Signal Processing · Electrical Eng. & Systems 2024-09-13 Alessio Burrello , Francesco Carlucci , Giovanni Pollo , Xiaying Wang , Massimo Poncino , Enrico Macii , Luca Benini , Daniele Jahier Pagliari

Photoplethysmography (PPG)-based blood pressure (BP) estimation is a challenging task, particularly on resource-constrained wearable devices. However, fully on-board processing is desirable to ensure user data confidentiality. Recent deep…

Depthwise separable convolutions are a fundamental component in efficient Deep Neural Networks, as they reduce the number of parameters and operations compared to traditional convolutions while maintaining comparable accuracy. However,…

Machine Learning · Computer Science 2024-06-19 Francesco Daghero , Alessio Burrello , Massimo Poncino , Enrico Macii , Daniele Jahier Pagliari

3D object detection from LiDAR sensor data is an important topic in the context of autonomous cars and drones. In this paper, we present the results of experiments on the impact of backbone selection of a deep convolutional neural network…

Computer Vision and Pattern Recognition · Computer Science 2022-10-03 Konrad Lis , Tomasz Kryjak

The rapid growth of artificial intelligence (AI) has made low-precision formats such as FP16, FP8, and, most recently, block-scaled FP4 the primary focus of modern GPUs, where Tensor Cores now deliver orders-of-magnitude higher throughput…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-19 Angelika Schwarz , Anton Anders , Cole Brower , Harun Bayraktar , John Gunnels , Kate Clark , RuQing G. Xu , Samuel Rodriguez , Sebastien Cayrols , Paweł Tabaszewski , Victor Podlozhnyuk

Pairwise sequence alignment is one of the most computationally intensive kernels in genomic data analysis, accounting for more than 90% of the runtime for key bioinformatics applications. This method is particularly expensive for…

Implicit neural representations have become pivotal in robotic perception, enabling robots to comprehend 3D environments from 2D images. Given a set of camera poses and associated images, the models can be trained to synthesize novel,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Sainan Liu , Shan Lin , Jingpei Lu , Alexey Supikov , Michael Yip

Deploying deep neural networks (DNNs) across homogeneous edge devices (the devices with the same SKU labeled by the manufacturer) often assumes identical performance among them. However, once a device model is widely deployed, the…

Machine Learning · Computer Science 2025-12-23 Kunlong Zhang , Guiying Li , Ning Lu , Peng Yang , Ke Tang

At the last step of short read mapping, the candidate locations of the reads on the reference genome are verified to compute their differences from the corresponding reference segments using sequence alignment algorithms. Calculating the…

Genomics · Quantitative Biology 2024-07-04 Zülal Bingöl , Mohammed Alser , Onur Mutlu , Ozcan Ozturk , Can Alkan

In recent years, the rapidly increasing number of reads produced by next-generation sequencing (NGS) technologies has driven the demand for efficient implementations of sequence alignments in bioinformatics. However, current…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-17 André Müller , Bertil Schmidt , Richard Membarth , Roland Leißa , Sebastian Hack

Real-time Deep Neural Network (DNN) inference with low-latency requirement has become increasingly important for numerous applications in both cloud computing (e.g., Apple's Siri) and edge computing (e.g., Google/Waymo's driverless car).…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-02-11 Weiwen Jiang , Edwin H. -M. Sha , Xinyi Zhang , Lei Yang , Qingfeng Zhuge , Yiyu Shi , Jingtong Hu

Genome sequence alignment is the core of many biological applications. The advancement of sequencing technologies produces a tremendous amount of data, making sequence alignment a critical bottleneck in bioinformatics analysis. The existing…

Hardware Architecture · Computer Science 2023-01-26 Weihong Xu , Saransh Gupta , Niema Moshiri , Tajana Rosing
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