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The current state of the art of Simultaneous Localisation and Mapping, or SLAM, on low power embedded systems is about sparse localisation and mapping with low resolution results in the name of efficiency. Meanwhile, research in this field…

Robotics · Computer Science 2019-02-14 Konstantinos Boikos , Christos-Savvas Bouganis

The substantial memory bandwidth and computational demands of large language models (LLMs) present critical challenges for efficient inference. To tackle this, the literature has explored heterogeneous systems that combine neural processing…

Hardware Architecture · Computer Science 2026-05-05 Yuzong Chen , Chao Fang , Xilai Dai , Yuheng Wu , Thierry Tambe , Marian Verhelst , Mohamed S. Abdelfattah

Dynamic programming (DP) algorithms, such as All-Pairs Shortest Path (APSP) and genomic sequence alignment, are fundamental to many scientific domains but are severely bottlenecked by data movement on conventional architectures. While…

Hardware Architecture · Computer Science 2026-03-02 Tsung-Han Lu , Weihong Xu , Tajana Rosing

Deploying deep neural networks (DNNs) across homogeneous edge devices (the devices with the same SKU labeled by the manufacturer) often assumes identical performance among them. However, once a device model is widely deployed, the…

Hardware Architecture · Computer Science 2025-12-16 Kunlong Zhang , Guiying Li , Ning Lu , Peng Yang , Ke Tang

Genomics is changing our understanding of humans, evolution, diseases, and medicines to name but a few. As sequencing technology is developed collecting DNA sequences takes less time thereby generating more genetic data every day. Today the…

Quantitative Methods · Quantitative Biology 2020-07-29 Sahand Salamat , Tajana Rosing

Wearable biosignal processing applications are driving significant progress toward miniaturized, energy-efficient Internet-of-Things solutions for both clinical and consumer applications. However, scaling toward high-density multi-channel…

Systems and Control · Electrical Eng. & Systems 2023-07-06 Sebastian Frey , Marco Guermandi , Simone Benatti , Victor Kartsch , Andrea Cossettini , Luca Benini

DNA read mapping is a computationally expensive bioinformatics task, required for genome assembly and consensus polishing. It requires to find the best-fitting location for each DNA read on a long reference sequence. A novel resistive…

Genomics · Quantitative Biology 2019-01-29 Roman Kaplan , Leonid Yavits , Ran Ginosar

An ever increasing number of computer vision and image/video processing challenges are being approached using deep convolutional neural networks, obtaining state-of-the-art results in object recognition and detection, semantic segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2016-11-11 Lukas Cavigelli , Luca Benini

Molecular fingerprints are the workhorse in ligand-based drug discovery. In recent years, an increasing number of research papers reported fascinating results on using deep neural networks to learn 2D molecular representations as…

Quantitative Methods · Quantitative Biology 2020-06-25 Yanxing Wang , Jianxing Hu , Junyong Lai , Yibo Li , Hongwei Jin , Lihe Zhang , Liangren Zhang , Zhenming Liu

3D reconstruction from videos has become increasingly popular for various applications, including navigation for autonomous driving of robots and drones, augmented reality (AR), and 3D modeling. This task often combines traditional…

Hardware Architecture · Computer Science 2022-12-19 Nobuho Hashimoto , Shinya Takamaeda-Yamazaki

To enhance the efficiency, scalability, and cross-survey applicability of stellar parameter inference in large spectroscopic datasets, we present a modular, parallelized Python framework with automated error estimation, built on the LAMOST…

Motivation: Recent advances in sequencing technologies promise ultra-long reads of $\sim$100 kilo bases (kb) in average, full-length mRNA or cDNA reads in high throughput and genomic contigs over 100 mega bases (Mb) in length. Existing…

Genomics · Quantitative Biology 2018-09-17 Heng Li

The rapid updates in error-resilient applications along with their quest for high throughput have motivated designing fast approximate functional units for Field-Programmable Gate Arrays (FPGAs). Studies that proposed imprecise functional…

Hardware Architecture · Computer Science 2022-06-29 Zahra Ebrahimi , Muhammad Zaid , Mark Wijtvliet , Akash Kumar

Predicting bioactivity and physical properties of molecules is a longstanding challenge in drug design. Most approaches use molecular descriptors based on a 2D representation of molecules as a graph of atoms and bonds, abstracting away the…

Quantitative Methods · Quantitative Biology 2020-10-27 William McCorkindale , Carl Poelking , Alpha A. Lee

Adam has proven remarkable successful in training deep neural networks, but the mechanisms underlying its empirical successes and limitations remain underexplored. In this study, we demonstrate that the effectiveness of Adam stems largely…

Machine Learning · Computer Science 2025-07-10 Hanyang Peng , Shuang Qin , Yue Yu , Fangqing Jiang , Hui Wang , Wen Gao

Nanopore sequencing accuracy is inherently limited by the quality of data from individual molecular translocation events, requiring advances beyond traditional sequencing-by-synthesis methods. We introduce an oxidized pyramidal sub-nm pore…

Applied Physics · Physics 2026-05-22 Jianxin Yang , Dehua Hu , Wu Yuan , Tianle Pan , Ho-Pui Ho

Early hardware limitations of GPU (lack of synchronization primitives and limited memory caching mechanisms) can make GPU-based computation inefficient. Now Bio-technologies bring more chances to Bioinformatics and Biological Engineering.…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-10-29 YuKun Zhong , BaoQiu Wang , JianBiao Lin , Chen Tao , Che Nian , Xie Wen

Deep neural networks (DNNs) have been proven to have many redundancies. Hence, many efforts have been made to compress DNNs. However, the existing model compression methods treat all the input samples equally while ignoring the fact that…

Machine Learning · Computer Science 2018-07-05 Zhisheng Wang , Fangxuan Sun , Jun Lin , Zhongfeng Wang , Bo Yuan

The widely adopted sequential variant of Non Maximum Suppression (or Greedy-NMS) is a crucial module for object-detection pipelines. Unfortunately, for the region proposal stage of two/multi-stage detectors, NMS is turning out to be a…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Rohun Tripathi , Vasu Singla , Mahyar Najibi , Bharat Singh , Abhishek Sharma , Larry Davis

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali