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A common approach in neuroscience is to study neural representations as a means to understand a system -- increasingly, by relating the neural representations to the internal representations learned by computational models. However, a…

Neurons and Cognition · Quantitative Biology 2025-08-14 Andrew Kyle Lampinen , Stephanie C. Y. Chan , Yuxuan Li , Katherine Hermann

With the increase in machine learning (ML) applications in different domains, incentives for deceiving these models have reached more than ever. As data is the core backbone of ML algorithms, attackers shifted their interest toward…

Cryptography and Security · Computer Science 2023-01-04 Kshitiz Aryal , Maanak Gupta , Mahmoud Abdelsalam

Neural networks have long strived to emulate the learning capabilities of the human brain. While deep neural networks (DNNs) draw inspiration from the brain in neuron design, their training methods diverge from biological foundations.…

Neural and Evolutionary Computing · Computer Science 2026-02-24 Joseph Bingham , Saman Zonouz , Dvir Aran

This paper presents a novel deep learning based method for automatic malware signature generation and classification. The method uses a deep belief network (DBN), implemented with a deep stack of denoising autoencoders, generating an…

Cryptography and Security · Computer Science 2017-11-27 Eli David , Nathan S. Netanyahu

We analyze algorithmic and computational aspects of biological phenomena, such as replication and programmed death, in the context of machine learning. We use two different measures of neuron efficiency to develop machine learning…

Neural and Evolutionary Computing · Computer Science 2022-07-12 Andrey Grabovsky , Vitaly Vanchurin

This paper proposes a novel method of classifying malware into families using high-resolution greyscale images and multiple instance learning to overcome adversarial binary enlargement. Current methods of visualisation-based malware…

Cryptography and Security · Computer Science 2023-11-22 Tim Peters , Hikmat Farhat

The representation of images in the brain is known to be sparse. That is, as neural activity is recorded in a visual area ---for instance the primary visual cortex of primates--- only a few neurons are active at a given time with respect to…

Computer Vision and Pattern Recognition · Computer Science 2017-01-25 Laurent Perrinet

Complex phenotypic differences among different acute leukemias cannot be fully captured by analyzing the expression levels of one single molecule, such as a miR, at a time, but requires systematic analysis of large sets of miRs. While a…

Quantitative Methods · Quantitative Biology 2015-12-23 Julián Candia , Srujana Cherukuri , Yin Guo , Kshama A. Doshi , Jayanth R. Banavar , Curt I. Civin , Wolfgang Losert

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive…

Active learning for classification seeks to reduce the cost of labeling samples by finding unlabeled examples about which the current model is least certain and sending them to an annotator/expert to label. Bayesian theory can provide a…

Cryptography and Security · Computer Science 2025-07-08 Ahmed Bensaoud , Jugal Kalita

Malware detection is a critical aspect of information security. One difficulty that arises is that malware often evolves over time. To maintain effective malware detection, it is necessary to determine when malware evolution has occurred so…

Cryptography and Security · Computer Science 2021-03-11 Sunhera Paul , Mark Stamp

Biomedical data are widely accepted in developing prediction models for identifying a specific tumor, drug discovery and classification of human cancers. However, previous studies usually focused on different classifiers, and overlook the…

Quantitative Methods · Quantitative Biology 2019-11-05 Shigang Liu , Jun Zhang , Yang Xiang , Wanlei Zhou , Dongxi Xiang

We propose a new kernel for biological sequences which borrows ideas and techniques from information theory and data compression. This kernel can be used in combination with any kernel method, in particular Support Vector Machines for…

Genomics · Quantitative Biology 2011-01-05 Marco Cuturi , Jean-Philippe Vert

Metagenomics characterizes the taxonomic diversity of microbial communities by sequencing DNA directly from an environmental sample. One of the main challenges in metagenomics data analysis is the binning step, where each sequenced read is…

Quantitative Methods · Quantitative Biology 2015-05-27 Kévin Vervier , Pierre Mahé , Maud Tournoud , Jean-Baptiste Veyrieras , Jean-Philippe Vert

Data diversity is critical to success when training deep learning models. Medical imaging data sets are often imbalanced as pathologic findings are generally rare, which introduces significant challenges when training deep learning models.…

Computer Vision and Pattern Recognition · Computer Science 2018-09-17 Hoo-Chang Shin , Neil A Tenenholtz , Jameson K Rogers , Christopher G Schwarz , Matthew L Senjem , Jeffrey L Gunter , Katherine Andriole , Mark Michalski

In an effort to catalog insect biodiversity, we propose a new large dataset of hand-labelled insect images, the BIOSCAN-Insect Dataset. Each record is taxonomically classified by an expert, and also has associated genetic information…

Modern computing systems have led cyber adversaries to create more sophisticated malware than was previously available in the early days of technology. Dated detection techniques such as Anti-Virus Software (AVS) based on signature-based…

Cryptography and Security · Computer Science 2022-01-20 Darren Cobian

Recent works have shown promise in using microarchitectural execution patterns to detect malware programs. These detectors belong to a class of detectors known as signature-based detectors as they catch malware by comparing a program's…

Cryptography and Security · Computer Science 2014-03-31 Adrian Tang , Simha Sethumadhavan , Salvatore Stolfo

This study presents the first large-scale empirical evaluation of quantum machine learning for predicting antibiotic resistance in clinical urine cultures. Antibiotic resistance is amongst the top threats to humanity, and inappropriate…

Other Quantitative Biology · Quantitative Biology 2026-01-23 Kahn Rhrissorrakrai , Filippo Utro , Alex Milinovich , Sandip Vasavada , Daniel Rhoads , Laxmi Parida , Glenn T. Werneburg

Malware authors have always been at an advantage of being able to adversarially test and augment their malicious code, before deploying the payload, using anti-malware products at their disposal. The anti-malware developers and threat…

Machine Learning · Statistics 2018-07-31 Vineeth S. Bhaskara , Debanjan Bhattacharyya