Related papers: Synchronization Implies Seizure or Seizure Implies…
The human brain is a directional network system of brain regions involving directional connectivity. Seizures are a directional network phenomenon as abnormal neuronal activities start from a seizure onset zone (SOZ) and propagate to…
Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…
Sleep is characterized by non-rapid eye movement (nREM) sleep, originating from widespread neuronal synchrony, and REM sleep, with neuronal desynchronization akin to waking behavior. While these were thought to be global brain states,…
We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…
Cortical network functioning critically depends on finely tuned interactions to afford neuronal activity propagation over long distances while avoiding runaway excitation. This importance is highlighted by the pathological consequences and…
Focal epilepsy is a devastating neurological disorder that affects an overwhelming number of patients worldwide, many of whom prove resistant to medication. The efficacy of current innovative technologies for the treatment of these patients…
In this study, we present a criterion based on the analysis of EEG signals through the mean of the conventional power spectral density (PSD) in the aim to localize and detect the epileptic area of the brain. Firstly, as the EEG signals are…
Epilepsy is one of the most common neurological disorders affecting up to 1% of the world's population and approximately 2.5 million people in the United States. Seizures in more than 30% of epilepsy patients are refractory to…
Focal cortical dysplasias (FCDs) are the most common cause of treatment resistant epilepsy affecting the pediatric population. Most individuals with FCD have seizure onset during the first five years of life and the majority will have…
Epilepsy affects nearly 1% of the global population, of which two thirds can be treated by anti-epileptic drugs and a much lower percentage by surgery. Diagnostic procedures for epilepsy and monitoring are highly specialized and…
Inferring patterns of synchronous brain activity from a heterogeneous sample of electroencephalograms (EEG) is scientifically and methodologically challenging. While it is intuitively and statistically appealing to rely on readings from…
We explore the use of neural networks trained with dropout in predicting epileptic seizures from electroencephalographic data (scalp EEG). The input to the neural network is a 126 feature vector containing 9 features for each of the 14 EEG…
When we look at the world around us, we see complex physical systems and emergent phenomena. Emergence occurs when a system is observed to have properties that its parts do not have on their own. These properties or behaviors emerge only…
Epilepsy is a disorder of the nervous system that can affect people of any age group. With roughly 50 million people worldwide diagnosed with the disorder, it is one of the most common neurological disorders. The EEG is an indispensable…
Epilepsy is a neurological disorder characterized by seizures and epileptic events intertwined with religious and personal beliefs since prehistoric times. This review paper explores the historical context and challenges in defining…
Epilepsy is one of the most common neurological diseases globally (around 50 million people worldwide). Fortunately, up to 70% of people with epilepsy could live seizure-free if properly diagnosed and treated, and a reliable technique to…
Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…
We report on the origin of synchronized bursting dynamics in various networks of neural spiking oscillators, when a certain threshold in coupling strength is exceeded. These ensembles synchronize at relatively low coupling strength and lose…
Electroencephalogram (EEG) is an important diagnostic test that physicians use to record brain activity and detect seizures by monitoring the signals. There have been several attempts to detect seizures and abnormalities in EEG signals with…
Ordered and disordered behavior in large ensembles of coupled oscillators map to different functional states in a wide range of applications, e.g., active and resting states in the brain and stable and unstable power grid configurations.…