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In this paper, we introduce SeizNet, a closed-loop system for predicting epileptic seizures through the use of Deep Learning (DL) method and implantable sensor networks. While pharmacological treatment is effective for some epilepsy…

We have studied neuronal synchronisation in a random network of adaptive exponential integrate-and-fire neurons. We study how spiking or bursting synchronous behaviour appears as a function of the coupling strength and the probability of…

Seizures are one of the defining symptoms in patients with epilepsy, and due to their unannounced occurrence, they can pose a severe risk for the individual that suffers it. New research efforts are showing a promising future for the…

Machine Learning · Computer Science 2021-08-09 Carlos H. Mendoza-Cardenas , Austin J. Brockmeier

Synchronization dynamics is a phenomenon of great interest in many fields of science. One of the most important fields is neuron dynamics, as synchronization in certain regions of the brain is related to some of the most common mental…

Neurons and Cognition · Quantitative Biology 2025-04-09 J. Used , J. M. Seoane , I. Bashkirtseva , L. Ryashko , M. A. F. Sanjuán

Oscillators coupled in a network can synchronize with each other to yield a coherent population rhythm. If multiple such networks are coupled together, the question arises whether these rhythms will synchronize. We investigate the impact of…

Adaptation and Self-Organizing Systems · Physics 2016-12-22 John Hongyu Meng , Hermann Riecke

To learn and reason in the presence of uncertainty, the brain must be capable of imposing some form of regularization. Here we suggest, through theoretical and computational arguments, that the combination of noise with synchronization…

Neurons and Cognition · Quantitative Biology 2013-12-06 Jake Bouvrie , Jean-Jacques Slotine

Synchronization of networked oscillators is known to depend fundamentally on the interplay between the dynamics of the graph's units and the microscopic arrangement of the network's structure. For non identical elements, the lack of…

Adaptation and Self-Organizing Systems · Physics 2016-01-20 A. Navas , J. A. Villacorta-Atienza , I. Leyva , J. A. Almendral , I. Sendiña-Nadal , S. Boccaletti

We study the synchronization of two model neurons coupled through a synapse having an activity-dependent strength. Our synapse follows the rules of Spike-Timing Dependent Plasticity (STDP). We show that this plasticity of the coupling…

Biological Physics · Physics 2009-11-07 Valentin P. Zhigulin , Mikhail I. Rabinovich , Ramon Huerta , Henry D. I. Abarbanel

Synchronization is studied in a spatially-distributed network of weekly-coupled, excitatory neurons of Hodgkin-Huxley type. All neurons are coupled to each other synaptically with a fixed time delay and a coupling strength inversely…

Soft Condensed Matter · Physics 2007-05-23 Yuqing Wang , Z. D. Wang , Y. -X. Li , X. Pei

Electroencephalography (EEG), as the most common tool for epileptic seizure classification, contains useful information about different physiological states of the brain. Seizure related features in EEG signals can be better identified when…

Signal Processing · Electrical Eng. & Systems 2018-05-15 Amirmasoud Ahmadi , Vahid Shalchyan , Mohammad Reza Daliri

Recognition of epileptic focal point is the important diagnosis when screening the epilepsy patients for latent surgical cures. The accurate localization is challenging one because of the low spatial resolution images with more noisy data.…

Computer Vision and Pattern Recognition · Computer Science 2013-03-05 A. Meena , R. Raja

Deep learning models have recently shown great success in classifying epileptic patients using EEG recordings. Unfortunately, classification-based methods lack a sound mechanism to detect the onset of seizure events. In this work, we…

Machine Learning · Computer Science 2025-03-04 Zheng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Synchronization of neural activity in the gamma frequency band is associated with various cognitive phenomena. Abnormalities of gamma synchronization may underlie symptoms of several neurological and psychiatric disorders such as…

Neurons and Cognition · Quantitative Biology 2024-07-02 Quynh-Anh Nguyen , Leonid L Rubchinsky

Objective: The aim of this study is to develop an efficient and reliable epileptic seizure prediction system using intracranial EEG (iEEG) data, especially for people with drug-resistant epilepsy. The prediction procedure should yield…

Neural and Evolutionary Computing · Computer Science 2019-04-09 Ramy Hussein , Mohamed Osama Ahmed , Rabab Ward , Z. Jane Wang , Levin Kuhlmann , Yi Guo

Epilepsy is one of the most serious neurological diseases, affecting 1-2% of the world's population. The diagnosis of epilepsy depends heavily on the recognition of epileptic waves, i.e., disordered electrical brainwave activity in the…

Signal Processing · Electrical Eng. & Systems 2023-06-26 Junru Chen , Yang Yang , Tao Yu , Yingying Fan , Xiaolong Mo , Carl Yang

Early management and better clinical outcomes for epileptic patients depend on seizure prediction. The accuracy and false alarm rates of existing systems are often compromised by their dependence on static thresholds and basic…

Signal Processing · Electrical Eng. & Systems 2025-01-29 Mathan Kumar Mounagurusamy , Thiyagarajan V S , Abdur Rahman , Shravan Chandak , D. Balaji , Venkateswara Rao Jallepalli

In clinical neuroscience, epileptic seizures have been associated with the sudden emergence of coupled activity across the brain. The resulting functional networks - in which edges indicate strong enough coupling between brain regions - are…

Applications · Statistics 2021-02-25 Xiaojing Zhu , Heather Shappell , Mark A. Kramer , Catherine J. Chu , Eric D. Kolaczyk

Seizure forecasting using machine learning is possible, but the performance is far from ideal, as indicated by many false predictions and low specificity. Here, we examine false and missing alarms of two algorithms on long-term datasets to…

Machine Learning · Computer Science 2021-10-27 Jens Müller , Hongliu Yang , Matthias Eberlein , Georg Leonhardt , Ortrud Uckermann , Levin Kuhlmann , Ronald Tetzlaff

By computerized analysis of cortical activity recorded via fMRI for pediatric epilepsy patients, we implement algorithmic localization of epileptic seizure focus within one of eight cortical lobes. Our innovative machine learning techniques…

Quantitative Methods · Quantitative Biology 2018-12-12 Rasoul Hekmati , Robert Azencott , Wei Zhang , Zili D. Chu , Michael J. Paldino

This article investigates the emergence of phase synchronization in a network of randomly connected neurons by chemical synapses. The study uses the classic Hodgkin-Huxley model to simulate the neuronal dynamics under the action of a train…

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