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Coherent diffraction imaging (CDI) is high-resolution lensless microscopy that has been applied to image a wide range of specimens using synchrotron radiation, X-ray free electron lasers, high harmonic generation, soft X-ray laser and…

Optics · Physics 2014-01-23 Jose A Rodriguez , Rui Xu , Chien-Chun Chen , Yunfei Zou , Jianwei Miao

We demonstrate numerical refocusing in coherent confocal laser scanning microscopy based on synthetic optical holography. This physics-based approach implements a computational propagation on the complex signal recovered in synthetic…

We report on a new x-ray imaging method, which combines the high spatial resolution of coherent diffraction imaging with the ability of dark field microscopy to map grains within thick polycrystalline specimens. An x-ray objective serves to…

Instrumentation and Detectors · Physics 2020-07-15 Anders Filsøe Pedersen , Virginie Chamard , Carsten Detlefs , Tao Zhou , Dina Carbone , Henning Friis Poulsen

Photoacoustic tomography leverages ultrasound's deep tissue penetration to retrieve optical absorption contrast well beyond the optical diffusion limit. Conventional photoacoustic systems rely on externally delivered light and are therefore…

Optics · Physics 2026-01-06 David C. Garrett , Lihong V. Wang

We propose an approach to far-field optical imaging beyond the diffraction limit. The proposed system allows image magnification, is robust with respect to material losses and can be fabricated by adapting existing metamaterial technologies…

Optics · Physics 2009-11-13 Zubin Jacob , Leonid V. Alekseyev , Evgenii Narimanov

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Optical microscopy has a diffraction limited resolution of about 250 nm. Fluorescence methods (e.g. PALM, STORM, STED) beat this, but they are still limited to 10 s of nm, and the images are an indirect pointillist representation of only…

Acquiring high-contrast optical images deep inside biological tissues is still a challenging problem. Confocal microscopy is an important tool for biomedical imaging since it improves image quality by rejecting background signals. However,…

Long-range active imaging has a variety of applications in remote sensing and target recognition. Single-photon LiDAR (light detection and ranging) offers single-photon sensitivity and picosecond timing resolution, which is desirable for…

Image and Video Processing · Electrical Eng. & Systems 2020-09-07 Zheng-Ping Li , Xin Huang , Yuan Cao , Bin Wang , Yu-Huai Li , Weijie Jin , Chao Yu , Jun Zhang , Qiang Zhang , Cheng-Zhi Peng , Feihu Xu , Jian-Wei Pan

Nonlinear optical microscopy allows rapid high-resolution microscopy with image contrast generated from intrinsic properties of the sample. Established modalities such as multiphoton excited fluorescence and second/third-harmonic generation…

Imaging techniques such as functional near-infrared spectroscopy (fNIRS) and diffuse optical tomography (DOT) achieve deep, non-invasive sensing in turbid media, but they are constrained by the photon budget. Wavefront shaping (WFS) can…

Optics · Physics 2026-04-21 Pablo Jara , Arthur Goetschy , Hui Cao , Alexey Yamilov

Localization-based imaging has revolutionized fluorescence optical microscopy and has also enabled unprecedented ultrasound images of microvascular structures in deep tissues. Herein, we introduce a new concept of localization optoacoustic…

Optics · Physics 2017-07-10 Xose Luis Dean-Ben , Daniel Razansky

Imaging below the diffraction limit is always a public interest because of the restricted resolution of conventional imaging systems. To beat the limit, evanescent harmonics decaying in space must participate in the imaging process. Here,…

Optics · Physics 2019-10-02 Tie-Jun Huang , Li-Zheng Yin , Ya Shuang , Jiang-Yu Liu , Yunhua Tan , Pu-Kun Liu

A miniaturized full-frequency encoded illumination (mini-FEI) chip is presented for high-throughput super-resolution imaging using the spatial frequency shift (SFS) effect. A tunable full SFS scheme is achieved through propagating and…

Coherent diffractive imaging is unique as the only route for achieving diffraction-limited spatial resolution in the extreme ultraviolet and X-ray regions, limited only by the wavelength of the light. Recently, advances in coherent short…

The Low Frequency Array (LOFAR) is an ideal instrument to conduct deep extragalactic surveys. It has a large field of view and is sensitive to large scale and compact emission. It is, however, very challenging to synthesize thermal noise…

Imaging of the optical properties of individual nanosystems beyond fluorescence can provide a wealth of information. However, the minute signals for absorption and dispersion are challenging to observe, and only specialized techniques…

Optics · Physics 2015-09-10 Matthias Mader , Jakob Reichel , Theodor W. Hänsch , David Hunger

In this paper, we present a novel reconstruction method for diffuse optical spectroscopic imaging with a commonly used tissue model of optical absorption and scattering. It is based on linearization and group sparsity, which allows…

Numerical Analysis · Mathematics 2019-03-06 Habib Ammari , Bangti Jin , Wenlong Zhang

The imaging depth of deep-tissue optical microscopy is governed by the performance of the gating operation that suppresses the multiply scattered waves obscuring the ballistic waves. Although various gating operations based on confocal,…

The field of biomedical imaging has undergone a rapid growth in recent years, mostly due to the implementation of ad-hoc designed experimental setups, theoretical support methods and numerical reconstructions. Especially for biological…

Biological Physics · Physics 2017-06-30 Daniele Ancora
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