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Dendritic spines, which are small protrusions on the dendrites of a neuron, are of interest in neuroscience as they are related to cognitive processes such as learning and memory. We analyse the distribution of spine locations on six…

Methodology · Statistics 2020-10-27 Heidi S. Christensen , Jesper Møller

We propose an inferential approach for maximum likelihood estimation of the hidden Markov models for continuous responses. We extend to the case of longitudinal observations the finite mixture model of multivariate Gaussian distributions…

Methodology · Statistics 2021-07-01 Silvia Pandolfi , Francesco Bartolucci , Fulvia Pennoni

We consider a stable Cox--Ingersoll--Ross process driven by a standard Wiener process and a spectrally positive strictly stable L\'evy process, and we study asymptotic properties of the maximum likelihood estimator (MLE) for its growth rate…

Statistics Theory · Mathematics 2019-08-23 Matyas Barczy , Mohamed Ben Alaya , Ahmed Kebaier , Gyula Pap

The estimation of absorption time distributions of Markov jump processes is an important task in various branches of statistics and applied probability. While the time-homogeneous case is classic, the time-inhomogeneous case has recently…

Statistics Theory · Mathematics 2022-07-26 Jamaal Ahmad , Martin Bladt , Mogens Bladt

In order to describe the extremal behaviour of some stochastic process $X$, approaches from univariate extreme value theory are typically generalized to the spatial domain. In particular, generalized peaks-over-threshold approaches allow…

Methodology · Statistics 2026-01-01 Max Thannheimer , Marco Oesting

In healthcare, the highest risk individuals for morbidity and mortality are rarely those with the greatest modifiable risk. By contrast, many machine learning formulations implicitly attend to the highest risk individuals. We focus on this…

Machine Learning · Statistics 2019-11-15 Yoonjung Kim , Jeremy C. Weiss

We address the problem of likelihood based inference for correlated diffusion processes using Markov chain Monte Carlo (MCMC) techniques. Such a task presents two interesting problems. First, the construction of the MCMC scheme should…

Statistical Finance · Quantitative Finance 2008-12-02 Konstantinos Kalogeropoulos , Petros Dellaportas , Gareth O. Roberts

We consider a random walk on a homogeneous Poisson point process with energy marks. The jump rates decay exponentially in the A-power of the jump length and depend on the energy marks via a Boltzmann--like factor. The case A=1 corresponds…

Probability · Mathematics 2015-05-14 P. Caputo , A. Faggionato , T. Prescott

We estimate a general mixture of Markov jump processes. The key novel feature of the proposed mixture is that the transition intensity matrices of the Markov processes comprising the mixture are entirely unconstrained. The Markov processes…

Methodology · Statistics 2022-04-12 Halina Frydman , Budhi Surya

Stochastic kinetic models (SKMs) are increasingly used to account for the inherent stochasticity exhibited by interacting populations of species in areas such as epidemiology, population ecology and systems biology. Species numbers are…

Computation · Statistics 2023-04-06 Tom E. Lowe , Andrew Golightly , Chris Sherlock

We investigate maxima of linear processes with i.i.d. heavy-tailed innovations and random coefficients. Using the point process approach we derive functional convergence of the partial maxima stochastic process in the space of…

Probability · Mathematics 2021-10-05 Danijel Krizmanić

We study recursive maximum likelihood estimation for stochastic interacting particle systems based on continuous observation of a single particle. In this regime, consistent estimation of the finite-particle log-likelihood is not possible,…

Methodology · Statistics 2026-05-04 Louis Sharrock , Nikolas Kantas , Grigorios A. Pavliotis

Markov chain Monte Carlo methods for exponential family models with intractable normalizing constant, such as the exchange algorithm, require simulations of the sufficient statistics at every iteration of the Markov chain, which often…

Computation · Statistics 2023-02-21 Quan Vu , Matthew T. Moores , Andrew Zammit-Mangion

Widely used closed product-form networks have emerged recently as a primary model of stochastic growth of sub-cellular structures, e.g., cellular filaments. In the baseline model, homogeneous monomers attach and detach stochastically to…

Probability · Mathematics 2020-07-30 Predrag Jelenkovic , Jane Kondev , Lishibanya Mohapatra , Petar Momcilovic

We study point processes on the real line whose configurations $X$ are locally finite, have a maximum and evolve through increments which are functions of correlated Gaussian variables. The correlations are intrinsic to the points and…

Probability · Mathematics 2010-10-26 Louis-Pierre Arguin , Michael Aizenman

An estimation method is proposed for a wide variety of discrete time stochastic processes that have an intractable likelihood function but are otherwise conveniently specified by an integral transform such as the characteristic function,…

Statistics Theory · Mathematics 2009-09-29 T. Merkouris

We propose two novel approaches for estimating time-varying effects of functional predictors within a linear functional Cox model framework. This model allows for time-varying associations of a functional predictor observed at baseline,…

Methodology · Statistics 2024-12-20 Hongyu Du , Andrew Leroux

In this paper we consider the problem of parameter inference for Markov jump process (MJP) representations of stochastic kinetic models. Since transition probabilities are intractable for most processes of interest yet forward simulation is…

Computation · Statistics 2014-09-16 Andrew Golightly , Darren J. Wilkinson

We show that each member of a broad class of Markovian population models induces a unique stochastic process on the space of genealogies. We construct this genealogy process and derive exact expressions for the likelihood of an observed…

Quantitative Methods · Quantitative Biology 2026-05-22 Aaron A. King , Qianying Lin , Edward L. Ionides

The marked Hawkes risk process is a compound point process for which the occurrence and amplitude of past events impact the future. Thanks to its autoregressive properties, it found applications in various fields such as neuosciences,…

Probability · Mathematics 2024-09-11 Laure Coutin , Mahmoud Khabou