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DNA methylation is an epigenetic mechanism that regulates gene expression by adding methyl groups to DNA. Abnormal methylation patterns can disrupt gene expression and have been linked to cancer development. To quantify DNA methylation,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Manahil Raza , Muhammad Dawood , Talha Qaiser , Nasir M. Rajpoot

Accurate and unbiased examinations of skin lesions are critical for the early diagnosis and treatment of skin diseases. Visual features of skin lesions vary significantly because the images are collected from patients with different lesion…

Image and Video Processing · Electrical Eng. & Systems 2025-02-20 Wei Dai , Rui Liu , Tianyi Wu , Min Wang , Jianqin Yin , Jun Liu

Electron and photon triggers covering transverse energies from 5 GeV to several TeV are essential for signal selection in a wide variety of ATLAS physics analyses to study Standard Model processes and to search for new phenomena. Final…

High Energy Physics - Experiment · Physics 2015-11-16 Gabriella Pásztor

The future Large Hadron electron Collider (LHeC) would allow collisions of an intense electron beam with protons or heavy ions at the High Luminosity-Large Hadron Collider (HL-LHC). Owing to a center of mass energy greater than a TeV and…

High Energy Physics - Phenomenology · Physics 2022-10-19 Subhasish Behera , Bernard Brickwedde , Matthias Schott

Clinical trials are crucial for drug development but are time consuming, expensive, and often burdensome on patients. More importantly, clinical trials face uncertain outcomes due to issues with efficacy, safety, or problems with patient…

Computers and Society · Computer Science 2022-03-15 Tianfan Fu , Kexin Huang , Cao Xiao , Lucas M. Glass , Jimeng Sun

Compared to hematoxylin-eosin (H&E) staining, immunohistochemistry (IHC) not only maintains the structural features of tissue samples, but also provides high-resolution protein localization, which is essential for aiding in pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yuhang Kang , Ziyu Su , Tianyang Wang , Zaibo Li , Wei Chen , Muhammad Khalid Khan Niazi

This talk summarises the ongoing proposals to upgrade the ATLAS and CMS detectors by the installation of forward silicon detector systems close to the beam line at distances of approximately 220 m and 420 m from the respective Interaction…

High Energy Physics - Experiment · Physics 2008-10-13 P J Bussey

For decades of catalysis research, the d-band center theory that correlates the d-band center and the adsorbate binding energy has successfully enabled the accelerated discovery of novel catalyst materials. Recent studies indicate that, on…

Large Language Models frequently generate fluent but factually incorrect text. We propose Adaptive Activation Cancellation (AAC), a real-time inference-time framework that treats hallucination-associated neural activations as structured…

Computation and Language · Computer Science 2026-03-12 Eric Yocam , Varghese Vaidyan , Gurcan Comert , Paris Kalathas , Yong Wang , Judith L. Mwakalonge

It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the standard multi-step Immunohistochemistry (IHC) staining is resource-intensive, expensive,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Peide Zhu , Linbin Lu , Zhiqin Chen , Xiong Chen

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

Understanding the effects of atomic structure modification in hematite photoanodes is essential for the rational design of high-efficiency functionalizations. Recently it was found that interface modification with Sn/Sb segregates…

Virtual staining of histopathology images (e.g., H&E-IHC) is an emerging tool in digital pathology, enabling faster and cheaper workflows by synthesizing target stains from routinely acquired slides. Yet, the quality of virtual staining…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Fedor Gubanov , Svetlana Illarionova , Vlad Kozlovskiy , Mikhail Romanov , Yersultan Akhmetov , Aida Akaeva , Vyacheslav Grinevich , Rifat Hamoudi , Maxim Sharaev

Helical molecules have been identified as potential candidates for investigating electronic transport, spin filtering, or even piezoelectricity. However, the description of the transport mechanism is not straightforward in single molecular…

The current state of cancer therapeutics has been moving away from one-size-fits-all cytotoxic chemotherapy, and towards a more individualized and specific approach involving the targeting of each tumor's genetic vulnerabilities. Different…

Biomolecules · Quantitative Biology 2019-07-02 Niranjan Balachandar , Christine Liu , Winston Wang

Hydroxymethylcytosine (5hmC) methylation is known to be a possible epigenetic mark impacting genome stability. In this paper, we address the existing 5hmC measure $\Delta \beta$ and discuss its properties both analytically and empirically…

Quantitative Methods · Quantitative Biology 2017-08-18 Alla Slynko , Axel Benner

It is foreseen to significantly increase the luminosity of the LHC in order to harvest the maximum physics potential. Especially the Phase-II-Upgrade foreseen for 2023 will mean unprecedented radiation levels, significantly beyond the…

Instrumentation and Detectors · Physics 2019-10-15 Marco Mandurrino

Protontherapy is hadrontherapy fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy superiority lies in its inverted depth-dose profile, hence tumour-confined irradiation. Protons, however, lack distinct…

An effective Hamiltonian is considered for hydrogen bonding between two molecules due to the quantum mechanical interaction between the orbitals of the H-atom and the donor and acceptor atoms in the molecules. The Hamiltonian acts on two…

Chemical Physics · Physics 2012-04-03 Ross H. McKenzie

The transformer models have shown promising effectiveness in dealing with various vision tasks. However, compared with training Convolutional Neural Network (CNN) models, training Vision Transformer (ViT) models is more difficult and relies…

Computer Vision and Pattern Recognition · Computer Science 2022-07-28 Jiawang Bai , Li Yuan , Shu-Tao Xia , Shuicheng Yan , Zhifeng Li , Wei Liu