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We present the current status of ongoing searches for molecular hydrogen in high-redshift (1.8 < zabs <= 4.2) Damped Lyman-alpha systems (DLAs) capitalising on observations performed with the ESO Very Large Telescope (VLT) Ultraviolet and…
Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial…
Lymph node (LN) metastasis status is one of the most critical prognostic and cancer staging factors for patients with resectable pancreatic ductal adenocarcinoma (PDAC), or in general, for any types of solid malignant tumors. Preoperative…
Superoxide reductase SOR is a non-heme iron metalloenzyme that detoxifies superoxide radical in microorganisms. Its active site consists of an unusual non-heme Fe2+ center in a [His4 Cys1] square pyramidal pentacoordination, with the axial…
N-heterotriangulenes (N-HTAs) represent a class of functional molecules with high potential for optoelectronic materials, for example as electron donating compounds in donor/acceptor (D/A) systems. The capability of two different N-HTAs,…
Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is…
Digitization of histopathology slides has led to several advances, from easy data sharing and collaborations to the development of digital diagnostic tools. Deep learning (DL) methods for classification and detection have shown great…
Magnetic resonance imaging (MRI) provides varying tissue contrast images of internal organs based on a strong magnetic field. Despite the non-invasive advantage of MRI in frequent imaging, the low contrast MR images in the target area make…
Structure-based virtual screening aims to identify high-affinity ligands by estimating binding free energies between proteins and small molecules. However, the conformational flexibility of both proteins and ligands challenges conventional…
ALICE (A Large Ion Collider Experiment) is one of four major experiments at the Large Hadron Collider (LHC) at CERN. The High Level Trigger (HLT) is a compute cluster, which reconstructs collisions as recorded by the ALICE detector in…
Hepatocellular carcinoma is the most spread primary liver cancer across the world ($\sim$80\% of the liver tumors). The gold standard for HCC diagnosis is liver biopsy. However, in the clinical routine, expert radiologists provide a visual…
Trans-activating transcriptional activator (TAT), a cell-penetrating peptide, has been extensively used for facilitating cellular uptake and nuclear targeting of drug delivery systems. However, the positively charged TAT peptide usually…
Using H2+ ions is expected to mitigate the two major impediments to accelerating very high currents in cyclotrons, due to lower space charge at injection, and stripping extraction. Planning for peak currents of 10 particle milliamps at 800…
The LHC experiments have analyzed the 7 and 8 TeV LHC data in the main Higgs production and decay modes. Current analyses only loosely constrain an anomalous top-Higgs coupling in a direct way. In order to strongly constrain this coupling,…
Head and neck cancers are the fifth most common cancer worldwide, and recently, analysis of Positron Emission Tomography (PET) and Computed Tomography (CT) images has been proposed to identify patients with a prognosis. Even though the…
As an important source of small molecule drugs, natural products show remarkable biological activities with their rich types and unique structures. However, due to the limited number of samples and structural complexity, the rapid discovery…
While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…
The syndecans represent an ongoing research field focused on their regulatory roles in normal and pathological conditions. Syndecan's role in cancer progression becomes well-documented, implicating their importance in diagnosis and even…
Developing an effective medicine to combat cancer and elusive stem cells is crucial in the current scenario. Withaferin A and Garcinol, important phytoconstituents of Withania somnifera (Ashwagandha) and Garcinia indica (Kokum)…
Damped Lyman-$\alpha$ Absorber (DLA), or HI 21cm Absorber (H21A), is an important probe to model-independently measure the acceleration of spectroscopic velocity ($v_\mathrm{S}$) via the Sandage-Loeb (SL) effect. Confined by the shortage of…