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Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and postgenomics data sets. Indeed, biological entities are not isolated, but are components of complex…

Quantitative Methods · Quantitative Biology 2018-05-07 Alex White , Matthieu Vignes

This paper attempts to make feasible the evolutionary emergence of novelty in a supposedly deterministic world which behavior is associated with those of the mathematical dynamical systems. The work was motivated by the observation of…

Adaptation and Self-Organizing Systems · Physics 2024-06-26 R. Herrero , F. Pi , J. Rius , G. Orriols

An extrapolation of the genetic complexity of organisms to earlier times suggests that life began before the Earth was formed. Life may have started from systems with single heritable elements that are functionally equivalent to a…

General Physics · Physics 2013-04-12 Alexei A. Sharov , Richard Gordon

The thermodynamic arrow-of-time problem is thought to be resolved by the observation that our universe initially was---and still is---far from equilibrium. The psychological arrow-of-time problem is often attributed the same resolution, but…

Cosmology and Nongalactic Astrophysics · Physics 2018-12-19 Lucas Johns

Even when concepts similar to emergence have been used since antiquity, we lack an agreed definition. However, emergence has been identified as one of the main features of complex systems. Most would agree on the statement ``life is…

General Physics · Physics 2025-12-22 Carlos Gershenson

It is a fascinating subject to explore how well we can understand the processes of life on the basis of fundamental laws of physics. It is emphasised that viewing biological processes as manipulation of information extracts their essential…

Quantum Physics · Physics 2007-05-23 Apoorva Patel

Computation, if treated as a set of physical processes that act on information represented by states of matter, encompasses biological systems, digital systems, and other constructs, and may be a fundamental measure of living systems. The…

Earth and Planetary Astrophysics · Physics 2024-07-09 Caleb Scharf , Olaf Witkowski

The molecular biology revolution of the last seventy five years has transformed our view of living systems. Scientific explanations of biological phenomena are now synonymous with the identification of the genes, proteins, and signaling…

Biological Physics · Physics 2024-10-29 Pankaj Mehta

In this paper we highlight the scopes of engineering bio-inspired political systems, which are political systems based on the properties of life that self-organize the increasing complexity of human social systems. We describe bio-inspired…

Adaptation and Self-Organizing Systems · Physics 2012-11-13 Nathalie Mezza-Garcia

We apply the theory of learning to physically renormalizable systems in an attempt to develop a theory of biological evolution, including the origin of life, as multilevel learning. We formulate seven fundamental principles of evolution…

Populations and Evolution · Quantitative Biology 2022-10-12 Vitaly Vanchurin , Yuri I. Wolf , Mikhail I. Katsnelson , Eugene V. Koonin

Living cells inherently reorganize their intracellular structures in response to mechanical cues from their environment. Among these responses, the formation of actin-based stress fibers exhibits a series of structural transitions depending…

Cell Behavior · Quantitative Biology 2026-04-20 Yuika Ueda , Shinji Deguchi

Unlike many physical nonequilibrium systems, in biological systems, the coupling to external energy sources is not a fixed parameter but adaptively controlled by the system itself. We do not have theoretical frameworks that allow for such…

Populations and Evolution · Quantitative Biology 2025-06-30 Ankit Dhanuka , Avi I. Flamholz , Arvind Murugan , Akshit Goyal

Biological and social systems are structured at multiple scales, and the incentives of individuals who interact in a group may diverge from the collective incentive of the group as a whole. Mechanisms to resolve this tension are responsible…

Populations and Evolution · Quantitative Biology 2023-05-31 Daniel B. Cooney , Simon A. Levin , Yoichiro Mori , Joshua B. Plotkin

Following extensive numerical experiments, it has been suggested that the evolution of competing computer programs in artificial life simulations shows signs of being a self-organized critical process. The primary evidence for this claim…

adap-org · Physics 2009-10-30 M. E. J. Newman , Simon M. Fraser , Kim Sneppen , William A. Tozier

The emergence of self-replication and information transmission in life's origin remains unexplained despite extensive research on the topic. A hypothesis explaining the transition from a simple organic world to a complex RNA world is…

Biomolecules · Quantitative Biology 2013-05-27 Stan Palasek

It has been proposed that, since the origin of life and the ensuing evolution of biological species, a second evolutionary process has appeared on our planet. It is the evolution of culture-e.g., ideas, beliefs, and artifacts. Does culture…

Populations and Evolution · Quantitative Biology 2019-07-09 Liane Gabora , Diederik Aerts

Actual causation is concerned with the question "what caused what?" Consider a transition between two states within a system of interacting elements, such as an artificial neural network, or a biological brain circuit. Which combination of…

Artificial Intelligence · Computer Science 2019-01-11 Larissa Albantakis , William Marshall , Erik Hoel , Giulio Tononi

The rich experiences of an intentional, goal-oriented life emerge, in an unpredictable fashion, from the basic laws of physics. Here I argue that this unpredictability is no mirage: there are true gaps between life and non-life, mind and…

History and Philosophy of Physics · Physics 2024-07-15 Simon DeDeo

The question "What is life?" has been asked and studied by the researchers of various fields. Nevertheless, no global theory which unified various aspects of life has been proposed so far. Considering that the physical principle for the…

Biological Physics · Physics 2020-07-21 Yasuji Sawada , Yasukazu Daigaku , Kenji Toma

Ecological systems are emergent features of ecological and adaptive dynamics of a community of interacting species. By natural selection through the abiotic environment and by co-adaptation within the community, species evolve, thereby…

Populations and Evolution · Quantitative Biology 2018-07-03 Katharina Brinck , Henrik Jeldtoft Jensen
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